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Tag: "amino" at biology news

UCLA AIDS Institute researchers find a peptide that encourages HIV infection

...s with HIV. RC-111 is also cyclic and has the same amino acid sequence as retrocyclin-1. In both peptides, the amino acids are strung like 18 beads along the molecule's backbone. The amino acids in RC-111, however, ar...

Scientists identify prion's infectious secret

...by subtle alterations in the recognition element’s amino acid sequence. While this prion is a laborator...t lab, published in Nature in 2005, identified the amino acid regions where prions connect with one another to form amyloids. Those interaction regions turn ...

Gene mutation linked to cognition is found only in humans

...on of type II neuropsin in humans, as the extra 45 amino acids in this form may cause protein structural and functional changes. They note that in order to understand the genetic basis that underlies the traits that set humans apart from nonhuman primates, recent studies have focused on identifying genes t...

The sound of proteins

...ncorporate rhythm, and how to cram the 20 standard amino acids (the building blocks of proteins) into just ...s of three adjacent bases that code for particular amino acids. They decided to include four different note durations with codons that appear more frequently...

Common treatment for methamphetamine overdose may damage brain cells

...s from the exaggerated stimulation of cells by the amino acid glutamate, which proves toxic to cells producing the neurotransmitter gamma-aminobutyric acid (GABA). Their results are published in the May 30 issue of The Journal of Neuroscience . "This work in laboratory animals raises immediate concerns...

New designer lipid-like peptide with lipid nanostructures for drug delivery systems

...ent a new class of designer materials using common amino acids, the same basic molecules from meat, beans and fruits. These lipid-like peptides have excellent potential to solubilize membrane proteins and enzymes, and - as now demonstrated - can also be utilized to stabilize different self-assembled liqui...

Weizmann Institute scientists develop a general 'control switch' for protein activity

...ineering, the scientists insert a short segment of amino acids into the amino acid sequence making up the protein. This segment is capable of binding strongly and selectively to ...

Gene responsible for common hearing loss identified for first time

...Netherlands. They found significant results for an amino acid changing SNP inTGBF1, and that this remained significant after correcting for multiple testing. Analysis of a large French group showed the same association. “Combining the data from both groups with a common odds ratio gave a very significa...

In nature, proteins sweep up nanoparticles

...tion. They found that the presence of cysteine, an amino acid that is a building block to most proteins, yielded the most extensive and prolonged aggregation, with some blobs measuring ten microns in diameter. Their discovery could also refine the search for the earliest indications of life on Earth, as...

Microbes at work cleaning up the environment

...de spheroids. They also studied whether various amino acids induce rapid aggregation in metal-sulfide na... cysteine locales. Cysteine is a sulfur-containing amino acid. Amino acids are the building blocks of proteins. The researchers found that inorganic aggre...

Researchers reveal structure of protein altered in autism

...oligins because of the similarity in structure and amino acid sequence with acetylcholinesterase....

Researchers shed light on mechanism of action used by anti-cancer drug

...ch proteins are synthesized from their constituent amino acids. However, the mechanism by which protein translation was inhibited by sorafenib remained largely unknown. In the present work, Grant and his team found that in human leukemia cells, sorafenib induces a process known as endoplasmic reticulum ...

Breakthrough developments in rheumatoid arthritis reported

...e comes in contact with arginine, one of 20 common amino acids in proteins. When one of the enzymes is present, nitrogen is removed from the chemical structure of arginine and it converts into citrulline. Laboratories have developed a test to measure for anti-cyclic citrullinated peptide antibody, or...

How to lose weight and not go hungry: HU researcher develops drug that mimics feeling of 'fullness'

...ptide (a peptide is a compound linking two or more amino acids) which can serve as an analog to the naturally occurring aMSH hormone. They were able to demonstrate that their peptide, which they call BL-3020, displayed good metabolic stability to intestinal enzymes when swallowed, and that it was able to c...

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