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Tag: "alter" at biology news

Newly discovered behavior in cancer cells signals dangerous metastasis

...vior and don't necessarily need a gene mutation to alter their behavior," said Sebastian Oltean, M.D., Ph.D., research associate and first author of the journal article. "Alterations in gene splicing can be much more subtle in nature but still have a major impact on the cancer cell and can be targets of ...

High HPV concentrations combined with smoking significantly raise risks of cervical cancer

...neoplastic growth, since HPV and smoking appear to alter the levels of certain cytokines, which are involved in controlling abnormal cell growth. More likely, the combination of both mechanisms are contributory factors. In any event, confirmation of an interaction between cigarette smoking and HPV in ce...

Research suggests beta agonists may alter the immune system

...ess or heart failure, may also have the ability to alter the immune system by increasing type 2 T cells, and thereby promote or worsen disease. "Although further research is needed to confirm that these findings occur in the human body, our research points to an important means by which the immune system...

Hormone linked to brain's cravings for food and other energy sources

... a reward. As a default, ghrelin's action may also alter seeking of drugs and substances that work through the same pathways. "We found that if we selectively block ghrelin in this part of the brain, we can suppress feeding or the need to seek out food and energy," said Horvath. "It also suggests that p...

'GreeneChip' -- New diagnostic tool that rapidly and accurately identifies multiple pathogens

...nt, particularly when early accurate diagnosis can alter treatment or assist in containment of an outbreak," stated W. Ian Lipkin, MD, director of the Greene Infectious Disease Laboratory at the Mailman School’s Department of Epidemiology. He added, "To address the challenges of emerging infectious diseas...

Cocaine high caused by interference in neuronal receiving stations

...eceptors also adjust themselves in complex ways to alter the sensitivity of the receiving neuron to stimulation. Researchers had long known that cocaine affects both dopamine and glutamate receptors on neurons, but the molecular details of those effects were unknown. In their experiments, Wang and collea...

New technique boosts size of proteins that can be analyzed

...nd acetylation of proteins add chemical groups and alter how a protein functions, such as modifying an enzymatic pathway. The bottom-up approach is limited because the samples seldom have masses that represent all the pieces of the protein, and masses can usually be matched to several combinations of piece...

Fantastic Voyage: A new nanoscale view of the biological world

...elling DNA with 15N. "These stable isotopes do not alter the DNA and are not toxic to people; with MIMS and stable isotope labelling we could track these cells, where they are and how they have changed several years later," says Lechene. "The most significant feature of this technique is that it opens ...

'Failed' experiment yields a biocontrol agent that doesn't trigger antibiotic resistance

...ineering. It is relatively easy for a scientist to alter a plasmid's genetic makeup and then transfer the plasmid into a bacterium. The host bacterium then replicates the recombinant plasmid and transfers copies of it to other bacteria in a process called conjugation. As he investigated the failed exper...

Discovery of the first resistance gene to rice yellow mottle virus

...n these varieties, the mutation does not appear to alter the protein's role in its primary biological functions, but can prevent its interaction with the virus which is then blocked in one of the stages of its infectious cycle. In parallel, a team of IRD virologists showed that it was possible to carry ...

Researchers link ocean organisms with increased cloud cover and potential climate change

...ing that can change global clouds can dramatically alter the impact of greenhouse gases on our changing climate. "It shows that there is still a lot we need to explore to better understand the delicate balance in nature," said Meskhidze. "It will require the cooperative efforts of researchers from man...

Edible coatings will be the packaging of the future

...exibility; while those containing glycerol did not alter their composition. Once the ideal plastifier for the coating was determined, it was observed that, in order to improve malleability, it was necessary to introduce a lot of glycerol. However, using high quantities of plastifier in a coating results in...

Gene therapy inhibits epilepsy in animals

.... Therefore, the researchers used gene delivery to alter the expression of the alpha1 subunit to see if this would have an effect on later seizure development. To carry the gene that alters the expression of the protein, they used an adeno-associated virus vector, injected into the rats' brains. The rese...

Global changes alter the timing of plant growth, scientists say

...l Preserve report evidence that climate change may alter this delicate balance. "In the natural world, species have evolved to be finely attuned to the seasons--timing is everything," said lead author Elsa Cleland, who performed this research as part of her doctoral dissertation at Stanford and is now a ...

Hundreds of thousands of viral species present in the world's oceans

... viruses are minute, self-replicating bundles that alter microorganisms' genetic material and moderate their communities through predation and parasitism. Despite their small size, they are astoundingly abundant with about as many of them in a bucket full of seawater as there are humans on the planet. As a...

Seagrass ecosystems at a 'global crisis'

.... They provide critical habitat for aquatic life, alter water flow and can help mitigate the impact of nutrient and sediment pollution. ...

Living view in animals shows how cells decide to make proteins

...t, and the order in which its RNA is assembled can alter an animal’s development. As a model system to s..., she said. Such subtle variations in proteins can alter the cell’s behavior, just as switching ingredients in a favorite recipe can change the food’s flavor...

NYU scientists identify how development of different species uses same genes with distinct features

...ommon genes to control their early development and alter how these genes are used to accommodate their own features. The findings, which were discovered by researchers in Professor Claude Desplan’s and Steve Small’s laboratories in NYU’s Center for Developmental Genetics, offer new insight into the working...

Does a peptide affect the heart's response to social isolation?

...red prairie voles (control group) oxytocin did not alter the cardiac responses. Conclusions These findings suggest that oxytocin can prevent damaging cardiac changes in adult female prairie voles exposed to social isolation. While there are limitations to the study, including the lack of spont...

Virtual duck bills demonstrate species coexistence

...s like sand and silt" said Gurd. "To do this, they alter the position of the upper and lower bill while they are feeding. This alters the size of the gap between the lamellae on the upper and lower bill, which allows them to determine the size of the particles they filter and ingest. By avoiding particle s...

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