New vaccine prevents CMV infection and disease in mice
...replication of the virus. These genes – which are also found in other herpes viruses such as chicken pox ...forces and attack the virus. Secondly, the vaccine also contains a “boost” from an inactivated virus, which generates an antibody response. Neither approac...St. Jude study shows genes play an unexpected role in their own activation
...specific genes in response to cAMP signals. It also suggests that the current model scientists use to ...te equally to activating a specific gene. The team also found evidence that other proteins can act as back-up co-factors for CBP/p300. “This more complex...A first -- Hebrew University scientist observes brain cell development in 'real time'
... into the network, adult-born neurons in the study also remained dynamic and capable of continuous change. This method provides a mechanism for observing, for the first time in a mammal, how a neuron develops into a rich and complex cell and how, once developed, neurons are maintained in the highly ac...Adult stem cells from human cord umbilical cord blood successfully engineered to make insulin
...sly thought to exist only in embryonic cells. They also found that, just as embryonic cells have been shown to do, these adult stem cells produced both C-peptide, a part of the insulin precursor protein, and insulin itself. Confirming the presence of the C-peptide was especially crucial, the researchers s...Experimental gene therapy 'abolishes' arthritis pain and lessens joint damage
...esearchers were surprised to find that the therapy also brought about a nearly 35 percent reduction in per... Piancino, of the University of Torino, Italy, was also an author based on an alliance between the two institutions. The study was funded in part by the Nat...Genome of Clostridium botulinum reveals the background to world's deadliest toxin
...hey have the deadly toxin. For each type, there is also a near-identical but harmless relative that lacks the toxin. C. sporogenes is the non-malignant, near twin of the organism sequenced. Professor Mike Peck, from the Institute of Food Research, commented that "It is astonishing that 43 per cent of t...'Smart' mice teach scientists about learning process, brain disorders
...k5, from the brain are continuing. The group is also beginning a search for drugs that might create the...’ but in doing so and applying this technology, we also found biochemical targets that hold promise for future treatments of a variety of cognitive disorder...Skimmed milk -- Straight from the cow
...ers producing only skimmed milk. The researchers also plan to breed commercial herds producing milk with...urated fats,’ according to Komorowski. This may also overcome the problem of waste. ‘If you can genetically produce milk without fat then that may turn o...Ants show us how to make super-highways
... of a majority to benefit the group as a whole. It also suggests that these benefits are a consequence of the unusual and derived foraging strategy of the army ant (Eciton burchellii). This highlights the importance of considering ecology and evolutionary history in the study of social organisation in ani...Researchers use MRI to predict recovery after spinal cord injury
... compromise (MCC) and length of lesion (LOL). They also looked at other factors, including bleeding within the spine, swelling and soft tissue injury. The results showed that severity of MSCC, bleeding and cord swelling were key indicators of a poor prognosis after SCI. Conversely, the absence of these...Avian influenza survivors' antibodies effective at neutralising H5N1 strain
...cked for funding by the UK's Wellcome Trust and is also supported by grants from the National Institutes o...d at the right time and at the right amount, could also provide a clinical benefit to humans with H5N1 infections." "In particular, we found that it was ...HIV and malaria combine to adversely affect pregnant women and their infants
... women protect themselves against malaria and have also discovered how the HIV virus works to counteract t...While the disease affects mostly children, malaria also severely affects pregnant women, especially during their first pregnancy, accounting for an estimate...Eavesdropping comes naturally to young song sparrows
...anguage learning, and Beecher thinks eavesdropping also could play a role in how infants learn language. Sparrows in the wild are thought to learn their songs in two phases. The first phase occurs in their first summer, when they hear and memorize songs sung by adult birds. The following spring, when...New research shows sharks use their noses and bodies to locate smells
... can not use just their noses to locate prey; they also need their skin – specifically a location called t...it had not been demonstrated that the lateral line also aids in the tracking of odor plumes. "Odor plumes are complex, dynamic, three-dimensional structur...Cytomegalovirus exacerbates atherosclerosis through an autoimmune mechanism
...votal role in the pathogenesis of the disease that also recognises a genetic influence. However, it is wel...vation not only of genes involved in apoptosis but also of many other genes that encode for proteins involved in different aspects of the atherosclerotic pr...New designer lipid-like peptide with lipid nanostructures for drug delivery systems
...d-like peptides interact with lipid molecules, but also may provide new strategies for the encapsulation a...teins and enzymes, and - as now demonstrated - can also be utilized to stabilize different self-assembled liquid crystalline nanostructures. Moreover, the ...Extra-aggressive form of idiopathic pulmonary fibrosis identified
...y and the lead author on this publication. "They also suggest that physicians should pay more attention to the time of onset of symptoms, and to look for other signs that allow the identification of these rapid progressor patients". In this study the authors performed global gene expression analysis...Gene expression patterns predict rapid decline in idiopathic pulmonary fibrosis patients
...tter decide a course of action." These findings also highlight the variability in the progression and outcome of IPF and may explain, in part, the difficulty in obtaining significant and reproducible results in studies of therapeutic interventions in patients with IPF, noted first author Moisés Selman,...For many insects, winter survival is in the genes
...wn of two such proteins. Denlinger and his team also examined the expression of one of those previously...eins we found during diapause in the flesh fly are also important to an insect's ability to endure months of cold temperatures." Denlinger has no plans t......Edmonton, Canada and the University of Lethbridge, also in Canada, showed that both species responded to t...For example, the females that weren't even mothers also ran to the speakers to help fawns. That would not be expected if females were simply trying to prote...