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Signal protein shows promise for blocking tumor promoters in skin cells

...everse tumor formation in skin. Seykora's team has already prepared an adenovirus and mice with the tumor-forming Src kinases expressed in their skin. Within six months, the group expects to know whether Srcasm can decrease squamous cell carcinoma formation in skin, mentions Seykora. ...

Fake pesticides threaten food safety

...will add to the list of successful action PSD have already taken against companies dealing in illegal pesticides. Twenty-four companies were issued with warnings in October at the British Crop Protection Conference in Glasgow for illegally promoting products. But Peter Sanguinetti, CEO of the UK Crop Prot...

Negative effects of caffeine are stronger on daytime sleep than on nocturnal sleep

...y at the Hôpital du Sacré-Coeur de Montréal. "We already knew that caffeine has important effects on nocturnal sleep. It increases the time taken to fall asleep, it increases the amount of awakenings, and it decreases the amount of deep sleep. We have shown that these effects of caffeine on sleep are way s...

Theory of oscillations may explain biological mysteries

...lore the implications for their subject. But it is already clear that coupled oscillating biological populations can give rise to potentially important effects such as “synchronized chaos? the interaction between two weakly competing consumers of a food resource can be transformed by the arrival of a third c...

Evolution of Old World fruit flies on three continents mirrors climate change

...e long term, this suggests that climate warming is already having genetic effects, at least on these organisms," Huey said. "The good news is that these flies may be able to adapt, at least to some extent, to a warming climate. However, organisms with longer intervals between new generations, humans or sequo...

Triple threat: World fin trade may harvest up to 73 million sharks per year

...is quite likely that sustainable catch levels have already been exceeded in some cases." The United Nations FAO compiles catch records for sharks and other fish, based on information submitted from member countries. Where possible, the FAO attempts to verify the accuracy of the figures, but verification of...

Protein structure initiative launches new resources for the scientific community

... phase of the PSI have been commercialized and are already being used in labs both large and small. Such advances include: The miniaturization of samples needed to grow, purify, and crystallize proteins; Robotic systems to handle samples and image crystals; Enhanced software to analyze stru...

New gene linked to bipolar disorder

... disorder cases. Previous studies of families have already shown that there are multiple genetic subtypes of the disorder, but progress in identifying the exact genes responsible has been slow because groups of families inherit different susceptibility genes. The Slynar gene is normally found in the brai...

Male contraception: One door opens, another closes

...avesca) (Human Reproduction, Oct. 25). The drug is already FDA-approved and on the market in both Europe and ...of the disease-treatment dose. With safety testing already out of the way, they thought this male "Pill" could potentially be brought to market very quickly. ...

Researchers seek to design first treatment for neuroAIDS

...dy of the drug's effect on neuroAIDs. CEP-1347 has already proven capable of reversing the neurotoxic effects of HIV proteins in living cells, according to research published in the July 1, 2006, edition of the Journal of Immunology. "We really don't know yet whether MLK or GSK-3b inhibitors will be superi...

Lost in the labyrinth

...Wingless pathway doesn't seem to damage cells that already exist. Thus beta-catenin seems to be a decision-maker, a selector of how information gets routed within the cell, rather than something which maintains the vitality of existing cells. Nerlov compares the breakdown to people standing at a fork in a ...

Cracking the egg

... events needed to create a viable organism. What's already in the egg that enables it to make the transition? How is it the same and how is it different across species? And what changes occur when the egg is fertilized? Scientists led by Drs Barbara Knowles and Alexei Evsikov at The Jackson Laboratory have c...

Heart smart: new drug improves blood flow

...enefits patients. Clinical trials of the drug have already started for the treatment of acute heart failure. Dr. Schmidt's team and colleagues in Germany and the US have previously shown that oxidative stress - the appearance of free radicals in the walls of arteries - is a key mechanism underlying cardiov...

'Protecting virus' offers instant flu protection and converts flu infections into their own vaccines

...quirted up the nose. Aerosol administration, used already for some vaccines, would be another way and is more user-friendly than injections. The protecting virus could also be a useful treatment for domestic animals. Ducks get a gut infection and chickens a combined gut and respiratory infection, so it ma...

Good times ahead for dinosaur hunters, according to U of Penn scientist's dinosaur census

...iversity take into account the number of dinosaurs already found, the rate of discovery and potential richness of the fossil locations that can be reasonably explored. They hold that it is still an open question as to whether their estimates of discoverable genera mirror the actual diversity of dinosaur gen...

Anticipation plays a powerful role in human memory, brain study finds

...re. That suggested that those subjects' brains had already started converting short-term memories of the images into longer-lasting ones. Mackiewicz says the anticipation of an uncomfortable situation probably kick-starts a kind of "arousal or fear circuitry" in the brain, which in turn helps to reinforce...

Transplanted brain cells hold promise for Parkinson's disease

...urately mimic what patients need." The researchers already have begun studies that delay the transplants unti...ee if the early protection/recovery holds up; he’s already past the three-month mark and to date, recovery is stable. While the rats needed immunosuppression b...

Scientists discover way to block growth of prostate cancer cells

... prostate cancer and to prevent recurrences in men already treated for primary tumours. Dr Hirak Basu told a news briefing at the EORTC-NCI-AACR [1] Symposium on Molecular Targets and Cancer Therapeutics in Prague today (Wednesday 8 November): "Previous work has demonstrated that androgen treatment increa...

Recycling technology

...echnological advances are so rapid that society is already discarding millions of LCD screens each year. There are no viable recovery techniques and no fully safe disposal options. Some 40 million LCD television sets were sold worldwide last year with expected sales likely to top 100 million by 2009. Now...

NYU biologists identify gene that coordinates two cellular processes

...xamine genes in the same module whose function has already been discovered. This approach has proven useful for learning about the roles of unknown genes. Unlike most genes in the network, mel-28 had connections to two distinct modules. Piano and Fernandez tested the idea that mel-28 plays important role...

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