How 'memory' T cells curb the spread of viruses throughout the body
...ode. “In fact we found that memory CD8 T cells already killed target cells in the lymph node and decreased viral spread to the liver and spleen when the virus just barely started to multiply.” Thus, memory CD8 T cells do not prevent infection; but prevent disease partly because they curb the spread of...Prey not hard-wired to fear predators
... protection. The states of Wyoming and Idaho have already proposed plans that would allow for as much as 85 percent of these once-protected wolves to be killed. So even as the goal of re-instilling fear of predators in prey species has been successful, the question remains whether enough wolves will be lef...Ancient retrovirus sheds light on modern pandemic
... "This ancient virus is a battle that humans have already won. Humans are not susceptible to it and have probably been resistant throughout millennia," said senior author Michael Emerman, Ph.D., a member of the Human Biology and Basic Sciences divisions at the Hutchinson Center. "However, we found that duri...AAAS decries latest stem cell veto
...l in the early stages of development and appear to already be eligible for NIH funding. AAAS strongly believe...l in the early stages of development and appear to already be eligible for NIH funding. AAAS strongly believes that it is only through federal support of diver...Experimental gene therapy 'abolishes' arthritis pain and lessens joint damage
...ead by an adeno-associated vector (AAV). AAVs have already been approved as safe for experimental gene therapy by the U.S. Food and Drug Administration, eliminating a tremendous regulatory hurdle. If successful, this next study will provide the proof of principle needed for the team to apply for phase I huma...Skimmed milk -- Straight from the cow
... is spreadable straight from the fridge. They have already identified a cow, Marge, with the genes required t...ealand cattle. New Zealand dairy firm Fonterra has already made milk products from Marge’s milk and they maintain the positive taste....Avian influenza survivors' antibodies effective at neutralising H5N1 strain
...ection in mice and neutralising the virus in those already infected. The research had been fast-tracked for funding by the UK's Wellcome Trust and is also supported by grants from the National Institutes of Health in the US and the Swiss National Science Foundation. The researchers found that the antibodi...Cytomegalovirus exacerbates atherosclerosis through an autoimmune mechanism
...ni in Genova, Italy. The same researchers have already shown that Cytomegalovirus infection can be responsible of the initial vascular lesions typical of the atherosclerotic process. The mechanism involved in the vascular lesion is of autoimmune origin: antibodies directed against particular proteins of ...Lessons from the orangutans: Upright walking may have begun in the trees
...ather than in more recent human ancestors that had already descended to the savannah, as current theory suggests. These findings appear in the 1 June 2007 issue of the journal Science , published by AAAS, the nonprofit science society. Upright walking, or bipedalism, has long been considered a definin...An 'elegant' idea proves its worth 25 years later
...cetate and sodium benzoate, two chemicals the body already makes to carry nitrogen for disposal in urine "jus...s elegant idea was to give patients chemicals they already make in small amounts in large doses to make up for the missing urea cycle enzyme they inherited," s...Mice with a migraine show signs of brain damage
...a visual disturbance, the changes to the brain are already well underway. To make the finding, the team used a sophisticated laser system known as two-photon imaging to look at the activity of live cells in the intact brain of a mouse. They combined that with a new technique to precisely measure how brain...'Personality-gene' makes songbirds curious
...e Royal Society London B, 2 May 2007). There is already evidence that variations (polymorphisms) in neurotransmitter-related genes are associated with personality differences among humans. Research from the last decade suggested a promising link between the Drd4-gene and the trait curiosity (novelty-seeki...pHLIP, a novel technology to locate and treat tumors
...alternative designs using the principles they have already established. ...Global survey of lizards reveals greater abundance of animals on islands than on mainland ecosystems
...z. “The consequences of island vulnerability have already been observed as island species account for half of known animal extinctions and a full 90 percent of known bird extinctions in the last 400 years. Our study suggests that islands will continue to be vulnerable worldwide.? “Many people, myself in...First clinical trial of gene therapy for childhood blindness
...nditions." The trial’s first operations have already taken place in young adult patients who developed the condition as children. Mr James Bainbridge, who leads the surgical team, said: "It is very encouraging that we can deliver genes to an extremely fragile site in the eye without complications." ...Corals -- More complex than you?
...out 10,000 genes ?but we’ve found almost that many already and clearly have a long way to go yet. "Based on the rate of gene discovery, we estimate that corals have as many as 20 or 25,000 genes, compared with the human complement of 20-23,000." Why a simple creature should have such a huge genetic rep...Newborn neurons like to hang with the 'in' crowd
...rentially reach out to mature brain cells that are already well connected within the established circuitry, r...nerative Diseases. "But if they are only replacing already existing connections there is less chance of error," he adds. Neurons make contact via specialize...Gene mutation linked to cognition is found only in humans
...n human, the weakening of the type I splicing site already existed in the common ancestor of humans and chimpanzees, implying a multi-step process that led to the dramatic change of splicing pattern in humans, the authors note. They identified a region of the chimpanzee sequence that has a weakening effect o...WHO data confirms low level of resistance to Tamiflu
...nt dose (75 mg twice daily) was given to a patient already exhibiting clinical symptoms, thus under-dosing the patient and increasing the risk of resistance.3 Once the twice daily treatment dose was provided, the patient recovered from her illness. Again this resistant virus was shown to cause less severe in...... relatively cheaper and more available. "It is already known that socio-economic inequalities in alcohol-related diseases are among the largest of any cause of death. For example, in Britain, between 1991 and 1993, liver cirrhosis rates among unskilled workers were about four times those experienced by p...