It's never too late to get it back! Aging interrupted
...of healthy people. The technique we have developed allows us to screen a relatively large number of drugs in months rather than years. The hope is that these drugs will be able to extend the lifespan of healthy animals, and possibly, after further testing, healthy humans? says Professor Spindler who will p...Scientists see DNA get 'sunburned' for the first time
...cules absorb light at specific wavelengths, and it allows researchers to study events that happen in less than a picosecond. They took specially designed strands of DNA -- ones made solely of thymine bases, in order to boost the chance of observing a reaction between adjacent thymines -- and exposed them...Investigating the measles virus as a tool to kill multiple myeloma
...ltiple myeloma, overexpress a protein, CD46, which allows them to evade destruction by the immune system. Laboratory strains of measles virus seek out this protein and use it as a receptor by which to enter the cancer cells. Upon entry, the virus spreads, infecting nearby tumor cells and fusing them togethe...Sandia researchers take new approach to studying how cells respond to pathogens
...ped tools, including: Microfluidics that allows researchers to do single-cell experiments Advanced imaging that allows researchers to image individual cells with much higher information content than possible with curren...UCI scientists reconstruct migration of avian flu virus
...eve. "The ability to develop the right mutation allows the virus to hop from one host type to the next," said Robert Wallace, UCI postdoctoral researcher and lead author of the study. "By spreading across a large area, the virus in essence can run multiple experiments in multiple locations, increasing th...Helium helps patients breathe easier
... are not so short of breath during exercise, which allows them to do more," said Dr. Neil Eves, lead author on the study. Eves conducted the study for his PhD dissertation at the University of Alberta. In the study 10 clinically stable men with moderate to severe COPD were each given four different mixes...Allergy to hair dye increasing
... and Sweden. Current European Union legislation allows PPD to comprise up to 6% of the constituents of hair dyes on the consumer market, but no satisfactory or widely accepted alternatives to these agents are available for use in permanent hair dye. Dermatologists report anecdotally that the frequency...Aspirin discovery may improve cancer treatments
...oteins in cells, which reduces cellular stress and allows protein synthesis to return to normal." Under conditions of cellular stress, eIF2Ą is phosphorylated by a group of proteins called stress-activated kinases. One of these is protein kinase R-like endoplasmic reticulum kinase (PERK). The resea...Researchers identify gene involved in dog size
...twork. The availability of the dog genome sequence allows researchers to better compare the human and dog genomes and narrow their search for genetic contributors to cancer and other major diseases. Researchers can access the dog sequence data through the following public databases: Dog Genome Resources ...MIT model helps researchers 'see' brain development
...he folds of the brain mathematically in a way that allows the researchers to analyze their changes over time and space. The original brain scan is then represented computationally with points. Charting each baby's brain requires about 130,000 points per hemisphere. Yu decomposed these points into a repr...UCSD researchers discover variants of natural tumor suppressor
...ake that, when on, slows the driver but when 'off' allows the driver to move. In cancer, we want the driver to brake, to prevent cell proliferation leading to tumor growth. But in diabetes, heart or neurological disease, where we want to promote cell growth and survival, we don't want to slow the driver d...Bypassing eggs, flu vaccine grown in insect cells shows promise
...oes not also include neuraminidase, an enzyme that allows a flu virus to replicate and spread. While the hemagglutinin is the focus of most vaccines, scientists have been curious to measure how a vaccine without neuraminidase performs. ...How appetite-stimulating brain cells work overtime during fasting
...ive hunger. The increase in mitochondria, in turn, allows the brain's hunger center to remain active when periods of food scarcity result in a "negative energy balance," said Sabrina Diano of Yale University School of Medicine, who led the study. Indeed, the researchers found, animals lacking either UCP2...Imaging techniques permit scientists to follow a day -- or four -- in the life of a cell
... latest in image-analysis software, this technique allows researchers to gain a long-term perspective on events in the lives of cells. ...Lithium builds gray matter in bipolar brains, UCLA study shows
...red brain volume in total, this new image analysis allows researchers to examine differences in cortical anatomy at a much greater spatial resolution. In this study, Bearden and colleagues at UCLA used computer analysis to analyze brain scans collected by collaborators at the University of Pittsburgh in...When your brain talks, your muscles don't always listen
...re based on sport, but my career in this field now allows me to address a much larger population that needs our knowledge," Knight said. "Exercise is still the means for improvement, and aging is a process that unites us all." ...Protein fragments sequenced in 68 million-year-old Tyrannosaurus rex
... highly sensitive mass spectrometry methods. "This allows you to get the chance to say, ‘Wait, they really are related because their sequences are related.?We didn’t get enough sequences to definitively say that, but what sequences we got support that idea." In another study appearing in the same issue o...Secret of worm's poison pill box protein could produce new natural insecticide
... element of the protein’s design. The hollow shape allows the protein to act as a receptacle for two other proteins (in the case of XptA1 these are XptB1 and XptC1). This forms a poison "complex" which makes the XptA1 300 times more toxic to the caterpillars than it would be by itself. As well as helping c...New protein inhibitor impedes growth of cancerous cells
...division, and a chemical inhibitor such as BI 2536 allows Plk1 function to be experimentally disrupted at specific points during the cell-division cycle, thereby revealing the normal roles of Plk1 in new detail, and potentially identifying specific cellular processes that might be targeted by future anti-ca......The rapid chain-reaction among the different pores allows the system to shut down extremely fast and can even memorize previous exposures," noted co-author Wolf Frommer. "Imagine a large animal marking its territory. A sudden flow of ammonia could be toxic to the plant. If it weren't for a rapid-fire shutdo...