Walking not enough for significant exercise benefits
...complete exercise at a moderate intensity, a level allowing for one or two sentences of conversation with ease. Intensity was not set for the walking group; they completed their daily exercise at a self-selected pace. "When we matched the two programs for energy expenditure, we found that the traditional fit...Coral reefs are increasingly vulnerable to angry oceans
... a threshold that can be scored on the same scale, allowing scientists to determine which coral will live and which will die. The scientists found that the most vulnerable corals are "table" corals, which have a broad flat top supported by a narrow stalk, making them more susceptible to strong wave forces ...New target for cancer therapy identified
...l in stem cells where it keeps the telomeres long, allowing the cells to keep dividing without limit which is necessary for the repair of damaged and worn out tissues throughout the human body. However, studies have shown that telomerase also plays a key role in the formation of cancerous tumours. "It's the...Insulin receptor stops progression of Alzheimer's disease
...ed by insulin, thus preventing them from dying and allowing them to communicate with each other. The major effects of the PPAR treatments were to increase brain size, preserve insulin and IGF-II receptor bearing neurons, and preserve learning and memory. "The trigger for dementia is the loss of insulin and I...New biochip helps study living cells, may speed drug development
...energy and transfer electrical signals. By quickly allowing ions in and out, they are useful for rapid cellular changes, the kind which occur in muscles, neurons and the release of insulin from pancreatic cells. The chip currently can detect individual levels of different ions. Porterfield believes that w...Molecular 'on/off switch' controls immune defenses against viruses
...ling process, preventing interferon production and allowing viral replication. Just how RIG-I signaling is normally regulated, however, hadn't been known. In the current study, UT Southwestern researchers found that RIG-I and LGP2 each contain a repressor domain, a sort of docking site that controls th...Stormy days ahead for coral reefs
... a threshold that can be scored on the same scale, allowing scientists to determine which corals will live and which will die. The most vulnerable corals are the table corals which have a broad flat top supported by a narrow stalk, making them more susceptible to strong wave forces than bushy or mounded ......dust from the ground and blow it toward the ocean, allowing the Bodélé valley to export the vast amount of dust that makes a life-sustaining contribution to the Amazon rainforest....Molecular anatomy of influenza virus detailed
...s a coat that is identical in each virus particle, allowing it to be studied by crystallography. The research team used electron tomography (ET) to make its discovery. ET is a novel, three-dimensional imaging method based on the same principle as the well-known clinical imaging technique called computerize...Mother birds give a nutritional leg up to chicks with unattractive fathers
...rienced by an offspring from a lower quality male, allowing females to supersede limitations of a suboptimal pairing on her own reproductive success. "For house finches, a species in which individuals are short-lived [and] present a high risk of death, a focus on the immediate reproductive attempts may be t...MIT nanoparticles may help detect, treat tumors
... magnetic signal than do individual nanoparticles, allowing detection by MRI. "We inject nanoparticles that will self-assemble when they are exposed to proteases inside of invasive tumors," said Sangeeta N. Bhatia, M.D., Ph.D., associate professor of the Harvard-MIT Division of Health Sciences & Technol...Tarantulas produce silk from their feet
...arantulas secrete silk from spigots on their legs, allowing them to better cling to surfaces. Until now, spide...ace, it produced silk from all four pairs of legs, allowing it to adhere to the glass for more than 20 minutes. The silk secretions were clearly visible on the ...Scientists solve 30-year-old mystery of mutant mouse's kidney woes
... Louis are the first to identify the mutated gene, allowing them to determine the mutation's effects and the origins of the disease. "The gene codes for a protein that moves water across membranes, and we showed that the mutated form of the protein doesn't get properly distributed in the urinary system," sa...Vaccine combined with short-term postexposure antibiotics protects monkeys from inhalational anthrax
... blood cells that would otherwise destroy it, thus allowing anthrax infection to progress. The toxins are thought to act mainly by damaging defensive cells called phagocytes, causing the immune system to malfunction. The organism then spreads unimpeded to all major organs of the body, causing tissue damage an...Embryo tests give parents the choice
...han 40 per cent of fertility clinics in the US are allowing couples to choose the sex of their child, a survey conducted by the Genetics and Public Policy Center (GPPC) in Washington DC suggests. The testing method, called preimplantation genetic diagnosis (PGD), was originally designed to test for severe or ...Scientists' cell discovery unearths evolutionary clues
...life style. "This provides a starting point in allowing us to examine what happens at the molecular level as species evolve and mutate," said Professor Schaap, of the Division of Cell and Developmental Biology in the College of Life Sciences at Dundee. "The availability of a family tree allows us to r...With record resolution and sensitivity, tool images how life organizes in a cell membrane
...ogs associated because a rope binds them together, allowing it to perform the function of floating, proteins associated with other proteins on a lipid raft may perform functions, Boxer said, though evidence for this is limited. These rafts may serve many functions such as reacting to stress, conferring immuni...Scientist works to improve treatment for brain tumors
...s delivered to the tumor through small cathethers, allowing physicians to determine the amount and specific location of treatment. "With the help of this research grant, we hope to optimize the clinical delivery of the advanced form of the drug," said Debinski. Debinski directs the Wake Forest Brain Tumor C...Iowa State researchers improving plastics made from corn and soy proteins
...pected to enhance the biodegradable plastics while allowing the researchers to use less base material to make the plastics. Grewell said the potential applications for plastics from crop proteins include disposable wraps for hay bales, pots for plants and packaging for the food industry. Grewell, Kessl......f tissues, causing the membranes to break down and allowing the cancer cells to escape into the bloodstream and to adjacent tissues. The result is metastasizing breast cancer. About 20 percent to 25 percent of breast-cancer patients were shown to have uPAR gene amplification, which means they carry too many c...