Gene Bridges And Covalys To Develop Restriction-Enzyme-Free SNAP-tag Gene Fusion Kits
...ut prior purification. The combined products will allow scientists to easily add the SNAP-tag gene onto an...s to be introduced later this year by Covalys will allow for immobilization without prior purification, and purification of SNAP-tag fusion proteins. "We ar...Investigating 'brain shrinkage' in alcoholics
...cesses ?similar to the root system of a tree ?that allow them to 'talk' with neighbouring neurons, often as...h as the shrinkage of dendrites, those fibers that allow neurons to "talk" with neighbouring neurons. "In experimental animals," he said, "these have been sh...Beetle-inspired switch uses water for bonding
...and nanoscales," said Steen. "We need devices that allow us to communicate between the two scales." Co-authors include Michael Vogel, a postdoctoral researcher in Cornell's Department of Chemical and Biomolecular Engineering, and researcher Peter Ehrhard at the Institute for Nuclear and Energy Technolog...Engineered molecule amplifies body's immune response
... certain cancers. Improving Stat1 efficiency would allow for much lower doses of interferon to be used, decreasing cost and side effect profile. In terms of diagnosis, it may be possible to screen patients for the level of Stat1 responsiveness to interferon, and if found to be low, that would make them can...Public collections of DNA and RNA sequence reach 100 gigabases
...tion, adds: "Today's nucleotide sequence databases allow researchers to share completed genomes, the genetic make-up of entire ecosystems, and sequences associated with patents. The INSDC has realized the vision of the researchers who initiated the sequence database projects, by making the global sharing o...Analysis of flower genes reveals the fate of an ancient gene duplication
...uplications are important because they effectively allow at least one of the gene copies to evolve while the (likely important) function of the original gene can remain intact. In this way, the duplication of pre-existing genetic information provides the raw material from which new gene functions can evolv...Discovering an ecosystem beneath a collapsed Antarctic ice shelf
...system beneath the collapsed Larsen Ice Shelf will allow scientists to explore the uncharted life below Antarctica's floating ice shelves and further probe the origins of life in extreme environments. Researchers discovered the sunless habitat after a recent underwater video study examining a deep glacial ...Genetic discovery could lead to drought-resistant plants
...l. "These genes are of paramount importance. They allow plants to adapt to changes in light, carbon and water availability. Ultimately, they shape the flux of carbon and water throughout entire ecosystems and affect the carbon cycle on a global-scale." The study was supported by the University of Toronto,...Crisis in African fish supplies looms, experts warn Africa leaders
... continent's estimated aquaculture potential could allow Africa to meet those targets, according to the analyses. In sub-Saharan Africa, however, aquaculture is currently so sparsely developed that an estimated 260% expansion in fish production from aquaculture there is needed by 2020 to maintain per cap...Chemical 'band-aid' prevents heart failure in mice with muscular dystrophy
...-first author of the study. He created a device to allow the simultaneous measurement of force and intracellular calcium concentration in individual myocytes as they are stretched. Yasuda's device uses microcarbon fibers stuck by electrostatic attraction to each end of a single cardiac myocyte. As the myoc...Leptin-signaling Protein Maintains Normal Body Weight And Energy Balance In Mice
... continent's estimated aquaculture potential could allow Africa to meet those targets, according to the analyses. In sub-Saharan Africa, however, aquaculture is currently so sparsely developed that an estimated 260% expansion in fish production from aquaculture there is needed by 2020 to maintain per cap...New Lab Research May Help Those Deafened By Immune System Attack
...er ear, home to the tiny, delicate structures that allow us to hear. Without warning, in days or weeks, patients lose the ability to hear in one or both ears. Some might get part or all of their hearing back if they take steroid medicines, but many are left to cope with partial or total deafness without kn...MicroRNA tweaks protein that controls early heart development
...f the Hand2 protein at precisely the right time to allow the proper development of heart muscle. "We think...ry in the early stages of embryonic development to allow proliferation and expansion of a pool of muscle progenitor cells that can eventually develop into th...Nanowires can detect molecular signs of cancer, scientists find
...ely depend upon the development of techniques that allow rapid detection of many markers with high selectivity and sensitivity. "Genomics and proteomics research has elucidated many new biomarkers that have the potential to greatly improve disease diagnosis," the scientists write. "The availability of mul...Researchers create infectious hepatitis C virus in a test tube
...orted in the June 9 issue of Science Express, will allow scientists to study every stage of the HCV life cycle and develop drugs to treat this life-threatening disease that affects more than 170 million people around the world. "The inability to reproduce aspects of the hepatitis C virus life cycle in cel...Hopkins scientists uncover 'tags' that force proteins to cell surface
...ts have discovered internal "shipping labels" that allow -- and perhaps force -- hundreds if not thousands of proteins to get to the surface of cells and stay there. Two natural proteins that use one of these "tags" are the ion channel that lets heart cells contract on cue, and the docking point that allow...Sleeping beauty plays a significant role in identifying cancer genes
...cancer. We believe the Sleeping Beauty method will allow us to identify many other such genes for other cancers." *Collier L., Carlson C., Ravimohan S., Dupuy A., Largaespada D. "Cancer gene discovery in solid tumours using transposon-based somatic mutagenesis in the mouse," Nature, Vol. 436, No. 7047. D...Why do aneurysms form? New studies suggest leading role for white blood cells
...ctin, a protein on the surface of neutrophils that allow them to attach to tissue. They studied L-selectin production in the aortas of rats that had been injured with elastase or exposed to control conditions. They also studied mice that had been genetically altered by U-M researchers to lack the gene for ...... well as a bacterial barrier but release ions that allow resistance to develop, Schultz said. The structure of the microbicidal coating and the complexity of the process make it nearly impossible for bacteria to become resistant to it, Schultz said. The coating comprises thousands of nitrogen clusters tha...... we now know that binding sites can be combined to allow a large number of expression outcomes using relatively few transcription factors." Others collaborating in the project were Jerzy Tiuryn of the Faculty of Mathematics, Informatics, and Mechanics at Warsaw University in Poland; Bartosz Wilczynski of ...