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Tag: "allow" at biology news

Census of Marine Life explorers surprised by diversity, density of Arctic creatures

...NA research made possible through this project may allow us to reconstruct the history of marine evolution." More than scientific curiosity drives this enterprise. The planet's polar regions are uniquely vulnerable to the effects of global climate change. They are reacting to the planet's gradual warming...

New miniaturised chip dramatically reduces time taken for DNA analysis

...t, the director of research. "Mass production will allow costs to be reduced and the product to become as widely available as pregnancy test kits we can buy at the local pharmacy". Electrochemical genosensors vs DNA chips Identifying DNA chains has become increasingly important in biochemistry, medicine ...

Researchers discover key gene involved in bark beetle pheromone production

... the beetles' monoterpene biosynthesis, which will allow further research into ways to disrupt the production of aggregation pheromone. In addition to Blomquist, Anna Gilg, Jeremy Bearfield, Claus Tittiger and William Welch co-authored the article, "Isolation and functional expression of an animal geranyl...

UCLA cancer researchers shake loose hidden biomarker

...ntigen (PSMA) in a location on the cell that would allow blood-borne immunotherapies to access the biomarker, transforming it from a hidden target into an exposed one. "In prostate cancer cells, PSMA is expressed in the apical region of the cell membrane, which blood can't reach, so injection of immunothe...

Researchers reveal secret of key protein in brain and heart function

...eate a molecule to disable it. That, in turn, will allow them to fully understand SAP97's role in the body. And that will point drug makers to targets for developing new ways to treat cardiac or neurological diseases. "To arrive at a solution, you need to understand the problem," Mierke said. "Solving pro...

Cancer drug slows poxvirus in mice

... could hamper the cell-to-cell spread of virus and allow the body's immune system to mount a successful defense, he explains. Experiments to test whether Gleevec might work against smallpox virus as well as against vaccinia virus are now being planned, Dr. Kalman says. "The approach of fighting disease by ...

Cancer related gene p53 not regulated as indicated by previous tissue culture research

...ving an accurate view of how p53 is regulated will allow the development of specific drugs that unleash the killing power of p53 by interfering with its negative regulators. Our cells are vulnerable to DNA breaks caused by UV light, ionizing radiation, toxic chemicals or other environmental damages. Unles...

Map of life on Earth could be used on Mars

...to measurable changes in the known geologic record allow researchers to date organisms with relative certainty. Blank can then use chronological data to analyze niche specialization, "where these organisms like to grow," among members of each life domain over geologic time. Habitat divergence among bacter...

Immune system's distress signal tells bacteria when to strike back

...ys to block or scramble the chemical messages that allow microbes to eavesdrop on their hosts or to conspire together to mount an attack. "We chose to study this in Pseudomonas because it is one of the deadliest infections for patients who undergo major surgery," said Alverdy. "We suspect something very s...

Scientists discover global pattern of big fish diversity in open oceans

... few remaining in formerly productive areas. If we allow these predators some reprieve, we could rebuild some of the lost biodiversity. "Our paper suggests there is a solution ?while some hotspots have already disappeared, there are still some very special places where species concentrate," says Worm. "We...

The making and breaking of microtubules

...-ray diffraction analysis. X?ray diffraction might allow higher resolution, but it would lose all informati...ntacts between the subunits are straight enough to allow lateral interaction between growing protofilaments. Says Nogales, "Such contacts appear semiconserve...

Recombinant DNA technology may enable oral, rather than injectable, delivery of protein drugs

...alifornia School of Pharmacy. This technology may allow for oral administration of drugs that previously could only be given by injection, notes Wei-Chiang Shen, Ph.D., professor and acting chair of the Department of Pharmaceutical Sciences. Shen, along with colleagues David Ann, Ph.D., professor of molec...

Fungus-farming termites descend from an African rain forest Eve

...such as wood and dry grass, to feed the fungus and allow it to flourish, while the fungus converts otherwise indigestible plant material into nutrients the termites can utilize. Earlier work had shown that in the evolutionary past, a single, unreversed, transition to agriculture occurred in which termites ...

Study: Well-known protein helps stem cells become secretory cells

...r secretion because all the components required to allow secretion to occur are 'turned on' very early in development." In order for any gene's instructions to be used to make a protein, the process of reading the instructions is jump-started by proteins called transcription factors. In the salivary gland...

Proteomics brings researchers closer to understanding microbes that produce acid mine drainage

...ment," Banfield said. "The proteomic approach will allow us to begin to understand how organisms change their behavior in response to the presence of other organisms and when their physical and chemical environments are perturbed." Coauthors with Banfield, Hettich and Thelen are post-doctoral fellow Rachn...

UCR chemist part of team identifying new areas of gene regulation

...eviously unknown location of a chemical opening to allow genetic transfers to occur. "We found acetylation at this site near the entry-exit points of the DNA superhelix as it wraps around the nucleosome is required for recruiting the nucleosome remodeling complex SWI/SNF and so regulates gene activity," h...

Using nanoparticles, in vivo gene therapy activates brain stem cells

... (ORMOSIL), the structure and composition of which allow for the development of an extensive library of tailored nanoparticles to target gene therapies for different tissues and cell types. A key advantage of the UB team's nanoparticle is its surface functionality, which allows it to be targeted to specif...

Researchers discover mechanism for multiplying adult stem cells

...onditions, it could be a powerful tool. "This may allow you to expand adult stem cells for therapy," observes Hochedlinger. "For instance, you could remove a person's skin tissue, put it in a dish, isolate the skin stem cells, then subject it to an environment that activates Oct4. This would cause the cel...

Deep thinking: Scientists sequence a cold-loving marine microbe

...y, Methé suggests, these subtle changes in biology allow C. psychrerythraea--and possibly similar bacteria--to thrive in the cold. More than just marvels of nature, cold-adapted enzymes hold industrial promise, as active ingredients in coldwater detergents, clean-up for industrial contaminants, and food tr...

Genetic links could unlock clues to leading cause of blindness

...ally establish that. This discovery, he said, will allow researchers to delve deeper into what causes the disease and could be the first step toward repairing the genetic defects linked to it. According to the National Eye Institute, nearly 2 million Americans have advanced age-related macular degeneratio...

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