Researchers unlock mechanism creating jigsaw puzzle-like plant cells
...and slenderness, provide the strength necessary to allow the plant to grow and thrive. The findings point out that these distinct signals play a critical role in the development of leaf cell walls and leaf structures in a controlled and ordered way and that genetically over expressing one or the other lea...New understanding of DNA repair may pave way to cancer treatments
... compounds that mimic the peptide's actions and to allow for further development of the peptide toward clin...in which ATF2 works is to halt the cell's cycle to allow repair of damaged DNA before such damage becomes permanent." Ronai and his colleagues are now deter...Insight into DNA's 'weakest links' may yield clues to cancer biology
...Duke, first author of the study. "The finding will allow us to develop a simple model to study fragile sites in a way that can't be done in more complex organisms." The findings suggest that mammalian and yeast fragile sites may have common features, an indication that a common mechanism may underlie thei...FDA Works To Speed The Advent Of New, More Effective Personalized Medicines
...ner for Operations, FDA. "This new technology will allow medicines to be uniquely crafted to maximize their...r is an Educated Consumer." This free session will allow members of the general public the opportunity to hear about the science behind personalized medicine...Maine Researchers Find Exceptions to Old Rules of Genetic Inheritance
...t than mapping the genome. The haplotype map could allow researchers to look for a single variation in the complex genetic code and know all the variations associated with it, since all are part of the same haplotype. The Maine research group challenges that proposal, demonstrating that genes within a hap...Biochemists report discovery of structure of major piece of telomerase; implications for cancer
...e research group. "Knowing the structure also will allow the pursuit of rational, structure-based drug design, and is a critical first step. The structure provides a potential target for drug intervention." Feigon emphasized that her laboratory conducts basic research, and is not involved in cancer treatm...Scientists discover that three overlapping signals in embryo help get the backbone right
...re among at least five that block other signals to allow the back, or dorsal, structures to form. Thirteen ...the same time in the embryo. While BMP antagonists allow the formation of the back and belly, another group of antagonists creates the head and tail, while a...Protein Discovery Could Unlock The Secret To Better TB Treatment
...id: "The discovery of Rpf in the TB bacteria could allow the development of methods to 'wake-up' all dormant bacteria in a patient allowing antibiotics to kill the bacteria and cure the disease." The team includes Prof Brian Henderson at the UCL Eastman Dental Institute, Nicholas Keep from Birkbeck, Unive...South African Tribunal Asks For Damages Estimates in GSK AIDS Drug Case
...k by South Africa's Competition Tribunal that will allow the complaint to go forward. GSK has sought outright dismissal of the case; however, the Competition Tribunal issued an order last week giving the complainants, AIDS Healthcare Foundation (AHF) and several South African AIDS advocates, 10 days to pre...Putting ecology back into river restoration
...l, geomorphological and ecological conditions that allow the river to be a resilient, self-sustaining system. The fourth criteria is to do no lasting harm. "For example, a channel modification project should minimise loss of native vegetation during river reconstruction, and should avoid the fish spawning ...Protein prevents detrimental immune effects of bacterial sepsis
... way our body controls responses to infections can allow the modeling of new therapeutics with lower side effects." The importance of this work is underscored by the fact that bacterial sepsis ranked among the top ten causes of death in both adults and neonates in 2002 in the United States (Natl Vital Sta...Measuring Enzymes At End Of Cancer Pathway Predicts Outcome Of Tarceva, Taxol
...f enzymes, which are the triggering molecules that allow a cell to grow and divide. CDK cell cycle enzymes are the end target of numerous cellular pathways that are involved in cancer development and progression, the researchers say. Before these studies, no one has been able to accurately test the functi...The lopsided brain: Attention bias is shared by humans and birds
...oneglect may reflect evolutionary adaptations that allow animals to devote attention to multiple aspects of their environment. The findings are reported in the May 24 issue of Current Biology by Bettina Diekamp (now at Johns Hopkins University) and colleagues at Ruhr University, Bochum, Germany; the Unive...Findings have implications for tracking disease, drugs at the molecular level
...ousands or millions of stain molecules. This could allow us, for instance, to track a single molecule of a drug in a cell or other biological sample." Other advantages of the technique are that the gold particles can be prepared easily, have very low toxicity, and can readily be attached to molecules of b......es in comparative genomic hybridization (CGH) will allow researchers to rapidly and reliably identify genet...and other cancers. "Agilent's CGH technology will allow us to study the entire genome in a manner that hasn't been possible in previous genomics research," ...Stanford gut check shows diversity of intestinal ecosystem
...r, small variations in the 16S rRNA gene sequences allow scientists to detect distinct bacteria. For each ... the use of microarray technology. The latter will allow them to analyze samples much more quickly. They have been working with biochemistry professor Patric...Low oxygen likely made Great Dying worse, greatly delayed recovery
...ven low-altitude passes had insufficient oxygen to allow animals to cross from one valley to the next. That population fragmentation likely increased the extinction rate and slowed recovery following the mass extinction, Huey said. "Biologists have previously thought about the physiological consequences o...Scientists reveal the shape of a protein that helps retroviruses break into cells
...ven low-altitude passes had insufficient oxygen to allow animals to cross from one valley to the next. That population fragmentation likely increased the extinction rate and slowed recovery following the mass extinction, Huey said. "Biologists have previously thought about the physiological consequences o...Successful Test Of Single Molecule Switch Opens The Door To Biomolecular Electronics
...an unusual configuration of the molecule that does allow the electrons from the electrodes to jump on to the molecule, a process first pointed out by Rudy Marcus of Cal Tech (for which he was awarded the 1992 Nobel prize in chemistry). The oligoaniline molecule the team tested has three electrical states:......rough in stem cell research ?a new tool that could allow scientists to harvest stem cells ethically - will be announced at the Institute of Physics' conference Physics 2005 in Warwick later today (Tuesday 12th April). Professor Josef Käs and Dr Jochen Guck from the University of Leipzig have developed a p...