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Researchers develop rapid diagnostic tool for pathogen identification

... in a couple of hours with minimal labor, and will allow comprehensive detection of co-infections.?/p> “The high multiplexing capability and sensitivity of the approach is provided by using the digital molecular weights of small molecules to code for the identity of the pathogens and detection of the m...

Molecular Motors Cooperate In Moving Cellular Cargo, Study Shows

...of a human hair). Recent improvements to FIONA now allow scientists to detect motion with millisecond time resolution. Selvin's team used FIONA to track fluorescently labeled peroxisomes (organelles that break down toxic substances) inside specially cultured fruit fly cells. This was the first time the im...

World-first Living Donor Islet Cell Transplant A Success; Procedure Offers Promise For Diabetics

...tion there. "Living donor islet transplants could allow many more desperate patients with type 1 diabetes to get successful islet transplants," says Dr. Shapiro. "The donor operation is relatively safe, but is not entirely devoid of serious potential risk," he added. A shortage of donor islet cells is th...

Programmable cells: Engineer turns bacteria into living computers

...computer models of their engineered systems, which allow them to study how small modifications would affect the ultimate behavior of the organisms. So far, said Weiss, the experimental results have matched the computer models fairly closely, but the goal is to have a mathematically exact description of how...

New online portal merges vast data on Gulf of Maine ecosystem

...ially inaccessible before now. Modern technologies allow us now to access these data in far more meaningful ways. This is a very big step toward understanding the diversity and distribution of life in the Gulf." Over the coming months, the website will be made even more dynamic by allowing users to visual...

Institute for Systems Biology Symposium Addresses Need for Better Computational Tools

...ctures. Understanding three dimensional structures allow researchers to identify the presumptive function of proteins. These functions can then be assigned to appropriate networks. Researchers expect that approximately 2/3 of the folded proteins will result in correct topologies and that approximately 1/3 ...

Transgenic plants remove more selenium from polluted soil than wild plants, new tests show

...lab. Getting inorganic selenium into gas form will allow it to just dissipate harmlessly into the atmosphere. No other form of remediation can do that." And what happens to the plants after they've soaked up their share of selenium? The researchers say that the plants can be harvested, dried and carefully...

50-year-old Mystery Solved: Protein Tags Regulate Key Ion Channel

...ting the cell from the outside world. Ion channels allow ions such as potassium, sodium and calcium to flow in and out and so are key regulators of many fundamental processes in biology. "Ions are the currency of the cellular world," explained Goldstein. "Cells collect some ions, others they discharge. Io...

Fibril Shape Is The Basis Of Prion Strains And Cross-species Prion Infection

...ibrils, and not the amino acid sequences, that may allow prions from one species to infect another. In a second Cell study, Jonathan Weissman and colleagues at the University of California, San Francisco came to the same conclusion in their experiments with yeast. They too discovered that the particular s...

Key mechanism in genetic inheritance during cell division identified

...and is largely electrostatic in nature. This could allow for lateral sliding or diffusion of Dam1 rings along microtubules. Analysis of the Dam1 rings after disassembly of microtubules, revealed an accumulation of rings at the ends of the microtubule, suggesting that the rings do not disassemble but slide ...

Researchers uncover sequence of major rice pathogen

...ase. The researchers identify novel receptors that allow the fungus to recognize its environment; secreted proteins that are likely used as offensive weapons to damage rice plants; and redundant, or duplicate, mechanisms that protect the fungus from efforts to fight against it. "It's a clever system," Dea...

First frozen egg baby born in Canada

...ing have been relatively unsuccessful because they allow the formation of ice crystals, damaging the cells and rendering the egg unusable. This problem has now been resolved by a new method of rapid freezing called vitrification developed at McGill by Dr. Ri-Cheng Chian, Scientific Director of the McGill R...

Solutions that reduce death of marine life reeled in by International Smart Gear Competition

...s before coming into contact with them, as well as allow them to escape unharmed if they still become entangled. To create avoidable, detectable, safer gear, the team tinkered with the chemical properties of the ropes. A group of scientists from the Central Institute of Fisheries Technology in India--Dr. ...

Defenseless plants arm themselves with metals

...arly all other plants. The molecule does, however, allow this group of plants, called metal hyperaccumulators, to store high levels of metal in their tissues, rendering them pathogen resistant. These findings, reported in today's (Friday, March 11) issue of the journal Plant Physiology, shed new light on ...

Some Brain Cells 'Change Channels' To Fine-tune The Message

...kins researchers have identified the proteins that allow specific brain cells to "change channels," a rare ...om, these brain cells are able to change what they allow in by swapping one kind of channel, or membrane opening, for another. Doing so lets the cells fine-t...

Same-Sex Mating Discovered in a Toxic Fungus

...uiting. The newly described mating strategy might allow a single mating strain to expand rapidly by cell division, yet retain its ability to generate diversity by undergoing sex, said Heitman. That diversity might provide an advantage when faced with new environmental challenges, he said. While the findi...

Genetic defects give the immune system the green light to attack the pancreas

...r have found genetic regions that, when defective, allow the immune system to attack the pancreas ?the first in a series of mis-steps that lead to type 1 diabetes. Armed with these findings published March 22 in the journal Immunity, the researchers are now trying to hone in on the exact genes involved, in...

Technique may allow cancer patients to freeze eggs, preserving fertility before starting treatment

A new technique might allow women diagnosed with cancer the opportunity to have children when chemotherapy and radiation treatments rob them of their fertility, researchers at the University of Michigan Comprehensive Cancer Center have found. By having her eggs frozen before s...

Medical whistleblowers speak out

...to examine and change all of the institutions that allow this synchrony to occur." In a related editorial, the PLoS Medicine editors explain why PLoS sponsored the roundtable and why they published Lenzer's account: "Lenzer's report will, we hope, spark discussion and debate about how American medicine - ...

Different microarray systems more alike than previously thought

... experts say, because these systems may ultimately allow scientists to uncover critical differences between, say, healthy and cancerous tissue. Unless laboratories can rely on each others' results, such findings would not have much value. For the study, 10 laboratories in the Washington, D.C./Baltimore ar...

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