Fibril Shape Is The Basis Of Prion Strains And Cross-species Prion Infection
...visiae yeast allowed prion transmission to Candida albicans yeast. The transmission event led to a new strain of Candida prion fibrils that could in turn infect Saccharomyces. Although fibril shape appears to be the deciding infective factor, amino acid sequence is still important because it defines a set of...Discovery may lead to better Candidiasis drug
...the cell membrane of the pathogenic fungus Candida albicans and allows the cell to regulate its volume. The b... were aware that histatin usually can keep Candida albicans in check in persons with enough saliva and a healthy immune system, but they did not know precisely ...CO2 sensing proves critical for fungal pathogens to adapt to life in air and human hosts
...O2 sensing in two major human fungal pathogens, C. albicans and C. neoformans. Both cause life-threatening, in...t is in atmospheric air (0.033%). Consequently, C. albicans and C. neoformans are exposed to dramatically elevated CO2 concentrations when causing systemic dise...Microscopic passengers to hitch ride on space shuttle
...la typhimurium, Pseudomonas aeruginosa and Candida albicans -- that have been identified as potential threats to crew health. Sending these microbes into space will allow scientists to investigate the microbes' genetic adaptation and ability to cause infectious disease in microgravity, and to better understan...Montreal researchers identify defects of immune cells
...ournal of Immunology. Oral and esophageal Candida albicans infections, which often affect individuals infecte...atients is often complicated by strains of Candida albicans resistant to conventional antifungal therapies. The research project was carried out jointly by Dr. ...U of M researchers discover genetic key to treating deadly fungal infections
...nt, university researchers have discovered that C. albicans can neutralize an antifungal drug by modifying one...gs, 10,000 die. The number of hospital-acquired C. albicans infections is increasing. There are few drugs available to treat it and the fungus often becomes res......rficial infections caused by fungi such as Candida albicans (the causative agent of thrush). "The class of drugs called azoles are able to kill off fungal infections by blocking the actions of one of its P450s that is essential for maintaining the cell structure," said Professor Munro. "We were able to sho...