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Recent breakthroughs in common adult leukemia highlighted in New England Journal of Medicine

When the most common adult leukemia in the United States was last reviewed by the New England Journal of Medicine (NEJM) in 1995, it was seen through the eyes of theories that dated back to the 1960s. As such, the journal recently invited three of the world's foremost experts on chronic lymphocytic leukemia (CLL) to write an authoritative update covering the transformation in the scientific commu...

Breakthrough Microarray-based Technology for the Study of Cancer

A new development in the analysis of cancer.has been announced by Agilent Technologies. The company has reported an.innovative method that enables the rapid advance of microarray-based.comparative genomic studies in cancer. According to the report.published in the December 24, 2004 issue of the Proceedings of the.National Academy of Science (PNAS) in collaboration with the National.Human Genome R...

Leukemia Drug Breakthrough Study In New England Journal Of Medicine

Alan List, M.D., leader of the Hematologic Malignancies Program at the H. Lee Moffitt Cancer Center & Research Institute, recently conducted a phase I/II trial of the experimental drug Revlimid showing promise as an innovative way to treat patients with myelodysplastic syndrome (MDS), a form of pre-leukemia. Given in pill form, Revlimid simultaneously blocks the growth of new blood vessels th...

Breakthrough method in nanoparticle synthesis paves the way for new pharmaceutical and biomedical applications

The Institute of Bioengineering and Nanotechnology (IBN) has developed a novel method to simultaneously control the size and morphology of nanoparticles, which can be used in pharmaceutical synthesis and novel biomedical applications. .. . Research Scientist Dr. Yu Han and IBN Executive Director Prof. Jackie Y. Ying have developed a fluorocarbon-mediated-synthesis technique that produces nanomete...

MUHC researchers make cancer target breakthrough

Researchers at the McGill University Health Centre (MUHC), in Montreal, have identified a new gene to combat cancer. In a new study, published in the on-line edition of the journal Clinical Cancer Research this week, the researchers document a reduction in the growth of both colon and lung cancer tumors with inhibition of the gene. . The new target gene is called methylenetetrahydrofolate reducta...

Breakthrough isolating embryo-quality stem cells from blood

A major breakthrough in stem cell research ?a new tool that could allow scientists to harvest stem cells ethically - will be announced at the Institute of Physics' conference Physics 2005 in Warwick later today (Tuesday 12th April). . .. Stem cells are cells which have not yet differ...

Breakthrough System for Understanding Ocean Plant Life Announced

Sixty million people in 36 countries of sub-Saharan Africa are threatened daily by a deadly parasitic disease known as African sleeping sickness. The disease is caused by organisms called trypanosomes, which are spread by the tsetse fly. African sleeping sickness affects approximately 500,000 people in sub-Saharan Africa, a quarter of whom will die this year. Because the trypanosome has an except...

Moffitt-USF head toward first human trials of anti-cancer drug that targets protein AKT

H. Lee Moffitt Cancer Center & Research Institute, working in partnership with the University of South Florida (USF), has discovered a new use for an old, previously discredited anti-cancer drug that could add another weapon in the arsenal against several cancers, including tumors of the breast, ovary, colon, skin and prostate. . The compound, tricirbine, was tested at various cancer centers...

Major breakthrough in the treatment of cancers and infectious diseases

Montreal researchers identify new anti-cancer, anti-infection response control mechanism .. . Dr. Veillette's team identified one of the ba...

Breakthrough: Scientists create world's tiniest organic particles

University of North Carolina at Chapel Hill chemists have developed what they believe is a breakthrough method of creating the world's tiniest manufactured particles for delivering drugs and other organic materials into the human body.Adapting technology pioneered by the electronics industry in fabricating transistors, the team has figured out for the first time how to create particles for carryi...

Science's Breakthrough of the Year: Watching evolution in action

Evolution has been the foundation and guiding theory of biology since Darwin gave the theory its proper scientific debut in 1859. But Darwin probably never dreamed that researchers in 2005 would still be uncovering new details about the nuts and bolts of his theory -- how does evolution actually work in the world of influenza genes and chimpanzee genes and stickleback fish armor? Studies that fol...

Breakthrough in micro-device fabrication combines biology and synthetic chemistry

Nanostructured micro-devices may be mass produced at a lower cost, and with a wider variety of shapes and compositions than ever before, for dramatic improvements in device performance by utilizing very small biologically produced structures. These entirely new biologically-enabled approaches are detailed in the current issue of the International Journal of Applied Ceramic Technology, published o...

Researchers report breakthrough against world’s deadliest viruses

Scientists from the Public Health Agency of Canada - with assistance from the U.S. Army Medical Research Institute of Infectious Diseases - have developed vaccines against the Ebola and Marburg viruses that have been shown to be effective in non-human primates. .....

Max Planck researchers make a breakthrough in plant stem cell research

Totipotent stem cells allow plants to build new organs throughout their whole life. But it has been unclear how hormones and genetic factors work together to prevent plants from having growth that is either stunted, or uncontrolled and tumor-like. Scientists from the Max Planck Institute for Developmental Biology have now uncovered a feedback mechanism, involving a growth-enhancing hormone and a...

Breakthrough for stem cell research

A University of New South Wales (UNSW) researcher based at the Diabetes Transplant Unit (DTU) at Sydney's Prince of Wales Hospital has produced a human embryonic stem cell (hESC) line without the use of any animal products. The breakthrough eliminates the risk of animal-to-human contamination in potential stem cell therapy treatments. . "This is the first hESC line produced in Australia and o...

Nanotech tools yield DNA transcription breakthrough

Rutgers researcher Richard H. Ebright and his collaborators have resolved key questions regarding transcription, the fundamental life process that was the subject of the 2006 Nobel Prize in Chemistry. . .. Two papers by Ebright and collaborators in the Nov. 17 issue of the journal Science define for the first time the mechanis...

Replacing insulin is top-ranked breakthrough foreseen for health in developing world

Eliminating the need for costly insulin injections for diabetics, regenerating heart muscle after it fails, and improving resistance to disease by engineering immune cells top a list of 10 potential breakthroughs for health in developing countries seen emerging from the new world of regenerative medicine, according to a study published today in the prestigious journal Public Library of Science (P...

T-ray breakthrough could make detecting disease far easier

A breakthrough in the harnessing of 'T-rays' - electromagnetic terahertz waves - which could dramatically improve the detecting and sensing of objects as varied as biological cell abnormalities and explosives has been announced. . .. Terahertz radiation, whose frequency is around one thousand billion cycles a second, bridges the gap b...

St. Jude announces breakthrough in eye cancer treatment

Scientists at St. Jude Children's Research Hospital have demonstrated in a mouse model a new, locally applied treatment for the eye cancer retinoblastoma that not only greatly reduces the size of the tumor, but does so without causing the side effects common with standard chemotherapy. The treatment also appears to be suitable for certain forms of breast, lung, prostate and colon cancer, and is s...

Stanford scientists make major breakthrough in regenerative medicine

Findings described in a new study by Stanford scientists may be the first step toward a major revolution in human regenerative medicine—a future where advanced organ damage can be repaired by the body itself. In the May 2007 issue of The FASEB Journal, researchers show that a human evolutionary ancestor, the sea squirt, can correct abnormalities over a series of generations, suggesting that a sim...

Breakthrough in understanding type-2 diabetes as key genes identified

The most important genes associated with a risk of developing type-2 diabetes have been identified, scientists report today in a new study. . .. The researchers identified four loci, or points on individuals' genetic maps, which corresponded to a risk of developing the disorder. The scientis...

Research on grey mould offers possible breakthrough in tomato cultivation

Tomato growers are likely to soon be able to cultivate new tomato varieties without having to use pesticides against grey mould (Botrytis cinerea). This is the conclusion of the STW-sponsored thesis by Richard Finkers from Wageningen University, with which he hopes to earn his doctorate on 3 April 2007. Finkers designed highly efficient methods whereby tomato varieties can be resistant to grey mo...

Breakthrough vaccine to treat chemo-resistant ovarian cancer

Cancer Treatment Centers of America announced today its plans to launch a new cancer vaccine therapy that expands treatment options for thousands of women with advanced stage ovarian cancer. This innovative treatment will be offered by Cancer Treatment Centers of America and developed by AVAX Technologies, Inc. (OTCMarket: AVXT.OB). . "Cancer Treatment Centers of America's number one priority is...

NT researchers discover breakthrough in malaria treatment

An article published in the prestigious international journal 'The Lancet' by researchers from the Menzies School of Health Research (MSHR) in Darwin has revealed a breakthrough in the battle to treat Malaria ?a disease which effects 40 per cent of the worlds population. . There are two major strains of malaria effecting humans, P. vivax and P. falciparum. Although attention focuses on the more...

UQ research heralds vaccine technology breakthrough

Respiratory syncytial virus (RSV) infection is a widespread infant illness that has been linked to asthma and can be deadly but may be curable by the development of this new vaccine technology by the Sir Albert Sakzewski Virus Research Centre and The University of Queensland's Faculty of Biological and Chemical Sciences. . .. About one in...

Breakthrough developments in rheumatoid arthritis reported

. Dr. Gregersen has finally closed the circle between key genes identified in his laboratory at the Robert S. Boas Center for Genomics and Human Genetics at The Feinstein Institute for Medical Research in Manhasset, NY and...
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