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New push for public health, AIDS spending at African Union summit

Activists hope this weekend's African Union (AU) summit will net commitments to boost government spending on public health, helping to curb the spread of AIDS, which killed 2.3 million Africans in 2004. .. .. . ."Now they have to deli...

A comprehensive response to HIV could prevent 10 million AIDS deaths in Africa by 2020

Based on successful animal studies, a novel.vaccine that uses immune cells as factories to produce Her2/neu protein.may offer a way to treat some human breast cancers, say researchers at.The University of Texas M. D. Anderson Cancer Center. [Ed : ].Their study, published in the online journal, Breast Cancer Research,.on Nov. 29, 2004, showed that the vaccine protected 86 percent of.experimental...

NYC's First Rapid HIV Drug-resistant AIDS Case Prompts Call to Step Up HIV Prevention

New York City's Public Health Department today issued a public health advisory after reporting the first documented case of an alarming, new, rapidly-progressing and highly drug resistant strain of HIV in a New York man who progressed from his initial HIV infection, thought to have occurred in mid-October 2004, to a largely untreatable strain of AIDS in just three months. . According to City heal...

New therapy for HIV/AIDS eliminates needles and excessive toxicity

A team led by Johns Hopkins scientists has.found the first clear evidence that the process behind the human immune.system's remarkable ability to recognize and respond to a million.different proteins might have originated from a family of genes whose.only apparent function is to jump around in genetic material.. .essentially cut themselves out of the genetic material, and scientists.have suspecte...

How an AIDS-Related Cancer Unleashes Inflammation

Although new HIV treatments have drastically reduced the incidence of Kaposi's sarcoma in developed countries, it remains a health threat in many developing countries. Now, researchers have discovered one way that Kaposi's sarcoma ?a cancer-like viral disease traditionally associated with AIDS ?triggers severe inflammation. .. . Ganem and McCor...

Norovirus, AIDS vaccine and Hepatitis Virus

Norovirus Prevalent in Those Suffering from Traveler's Diarrhea .. . It is estimated that 20 to 50 percent of the people traveling to tropical areas of the world will experience traveler's diarrhea (TD). TD, defined as three or more loose stool movements in a 24-hour period, frequently results from exposure to bact...

Brain-mapping technique aids understanding of sleep, wakefulness

The power of a new technique to map connections among nerve cells in the brain has a UT Southwestern Medical Center scientist dreaming of solving the mysteries of sleep. .. . The findings, available online and appearing in the April 21 issue of t...

FDA Announces Series of Changes to the Class of Marketed Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)

The Food and Drug Administration (FDA) today announced a series of important changes pertaining to the marketing of the non-steroidal anti-inflammatory class of drugs, including COX-2 selective and prescription and non-prescription (over-the-counter (OTC)) non-selective NSAID medications. A list of these products is available on the Internet at http://www.fda.gov/cder/drug/infopage/cox2/default.h...

South African Tribunal Asks For Damages Estimates in GSK AIDS Drug Case

A landmark South African legal complaint against British drug maker GlaxoSmithKline (GSK) over its AIDS drug pricing and policies in that country will proceed following an order late last week by South Africa's Competition Tribunal that will allow the complaint to go forward. GSK has sought outright dismissal of the case; however, the Competition Tribunal issued an order last week giving the comp...

Supercomputers to focus brains on AIDS dilemma

More than two decades after it burst onto the scene, HIV/AIDS has claimed more than twenty million lives and continues to devastate societies around the world, particularly in Africa and other developing countries. In the late 1980s and early 1990s, after years of effort AIDS researchers succeeded in developing a class of drugs that proved to be highly effective against AIDS. By blocking the acti...

AIDS Public Awareness Campaign Expands Following Report Of Rapidly Progressive HIV

State Health Commissioner Antonia C. Novello, M.D., M.P.H., Dr.P.H., today announced the expansion of New York State's HIV/AIDS Public Awareness and Education campaign to help combat the potential spread of HIV and further protect New Yorkers from the virus that causes AIDS. .. Dr. Novello said, "In light of recent reports of a drug-resistant, rapidly progressive strain of HIV in New York City, w...

Hopkins AIDS experts issue warning about global efforts to provide drug therapies

Johns Hopkins infectious disease specialists who have spent more than two decades leading efforts to combat HIV and AIDS worldwide are warning that limited international relief supplies of antiretroviral therapies currently being distributed in Africa, Asia and the Caribbean will not get to those who can least afford to pay for them. . In an article appearing in the American Journal of Public Hea...

FDA approves more generic AIDS drugs

Experimenting with Arabidopsis, a fast-growing cousin of the humble mustard plant, scientists at the University of North Carolina at Chapel Hill got a big surprise while investigating how plants respond to attacks from disease organisms such as bacteria and viruses. . "Contrary to what we thought we'd find, our experiments showed that at least three different proteins work in concert with one ano...

President Bush's cut to AIDS prevention in Africa would be devastating

Twenty-eight years after intense selective logging stopped in the region now known as Uganda's Kibale National Park, the red-tailed guenon (Cercophithecus ascanius) is a primate still in decline. The logging practice, scientists report in a new study, changed the ecological balance for these monkeys, leading to behavioral changes and opening the door for multiple parasitic infections. . The resea...

FDA approves child-friendly AIDS medicine

A new website with a Global Information System will provide valuable information for assessing environmental hazards caused by Hurricane Katrina. The National Institute of Environmental Health Sciences (NIEHS), one of the National Institutes of Health, created the website to provide the most up-to-date data to public health and safety workers on contaminants in flood waters, infrastructure and in...

Laboratory professionals in Africa receive training under AIDS Relief Plan

The American Society for Clinical Pathology (ASCP) announced that the Society will receive approximately $1.5 million in federal funds to continue to provide laboratory training and quality improvement programs in African countries severely affected by AIDS. The training programs are for medical laboratory professionals in Africa and will continue in 2006 through the President's Emergency Plan f...

South Africa still debating how to tackle HIV/AIDS when 5 million are infected

A national conference in South Africa was dominated this week by the continuing debate over HIV/AIDS drugs. Health Minister Manto Tshabalala-Msimang repeated yet again that drugs were not the only way to fight HIV/AIDS, and that eating habits were also important. .. . The minister in the past has been nicknamed Dr. Garlic because of some of her...

AIDS expert says global strategy needed to combat feminization of HIV/AIDS

Thomas C. Quinn, M.D., a Johns Hopkins physician and scientist, who has spent the best part of the last 25 years leading major efforts to combat HIV and AIDS throughout the world, is calling for global strategies and resources to confront the rapid "feminization" of the AIDS pandemic. . .. According to Quin...

Protein structure key for AIDS, cell function

Cornell University researchers have discovered the 3-D crystal structure of a protein, human CD38, which may lead to important discoveries about how cells release calcium -- a mineral used in almost every cellular process. The findings also may offer insights into mechanisms involved in certain diseases, ranging from leukemia to diabetes and HIV-AIDS. . .. As one example, researchers have shown...

Progress on HIV/AIDS significant but insufficient

United Nations Secretary-General Kofi Annan shared his hope with a gathering of senior world officials at Headquarters that the 2001 Declaration of Commitment on HIV/AIDS would have heralded a response that matched the epidemic's scale, yet progress had been "significant but insufficient". . Citing achievements in the core areas of political leadership, funding, the intensity and reach of prevent...

UF scientist finds unexpected link between cat and human AIDS viruses

Emerging relationships between the two viruses could one day lead to a vaccine for human .. . The surprise finding may mean cats with feline immunodeficiency virus, also known as FIV or feline AIDS, could eventually be treated even more effectivel...

New classification of eukaryotes has implications for AIDS treatment, agriculture and beyond

New classification conveys important information about the biochemistry and metabolism of disease-causing organisms. The new classification recognizes 6 major clusters of organisms, rather than the 4 traditional Kingdoms. . Here are three examples. 1) Pneumocystis, an opportunistic pathogen causing mortality in AIDS patients and immunocompromised individuals, is now known to be a fungus, indicat...

Study uncovers placental microtransfusions lead to transmission of AIDS virus during childbirth

Transmission of HIV, the virus that causes AIDS, from pregnant women to their infants sometime during childbirth is a huge international problem, studies have shown. Between 25 percent and 35 percent of babies born to untreated HIV-infected mothers become infected themselves. . .. "The question has always been how does the virus get from the mothers to the babies?" said principal investigator Dr....

A new step towards an AIDS vaccine

Progressive disease after HIV infection is inversely correlated with the presence of plasmacytoid dendritic cells (pDCs), a subset of the dendritic cell family and the major producers of type 1 interferon in the body. High numbers of pDCs is related to successful control of HIV. In a paper appearing online on October 13 in advance of print publication of the November issue of the Journal of Cli...

2005 AIDS figures released by WHO and UNAIDS

Editor : Be sure to check out the .. There is new evidence that adult HIV infection rates have decreased in certain countries and that changes in behaviour to prevent infection—such as increased use of condoms, delay of first sexual experience and fewer sexual partners—have played a key part in these declines. The new UN report also indicates, however, that overall trends in HIV transmission are...

Infant transplant patients resist infections that kill adult AIDS patients

Investigators have discovered that some type of protective system goes into action in some cases when a baby's immune system is deficient. This discovery indicates a hidden safety net that might have far-reaching consequences for treating diseases of the immune system such as AIDS. The Mayo Clinic-led study was conducted with colleagues in Toronto and Baltimore, and is reported in the early onlin...

Combination therapy improves AIDS-related lymphoma outcome

Combining aggressive HIV therapy and chemotherapy significantly improves the survival rates of HIV-positive men and women treated for lymphoma, according to a new study. . ), a peer-reviewed journal of the American Cancer Society, the study reveals that combination therapy showed the greatest benefit for HIV patients suffering from aggressive malignant non-Hodgkin's lymphoma. This benefit was mo...

Study shows AIDS drugs cost-effective, care underfunded

New research shows that highly active antiretroviral therapy (HAART) is very cost-effective, despite the high price tag. However, the study also shows that reimbursement to physicians treating patients with HIV is critically low, threatening patients' access to care. The study findings are reported in the April 1 issue of Clinical Infectious Diseases, now available online. . While HAART has led t...

Free HIV tests cheaper than charging when goal is preventing AIDS

Offering free HIV tests instead of charging a small fee is more cost-effective at preventing HIV infections and draws in three times as many people for testing, according to a Duke University Medical Center study conducted in Tanzania. . The Duke researchers provided free HIV tests and counseling during a two-week pilot program in 2003. The number of people seeking tests increased from 4.1 per d...

HIV/AIDS rates in Tijuana, Mexico increasing at alarming rate

A study by researchers at the University of California, San Diego (UCSD) School of Medicine indicates that the rate of HIV/AIDS infection in Tijuana, Mexico is increasing, and much higher than had been previously estimated. The findings are based on data compiled by a team of researchers working in San Diego and Mexico to create a population-based model in order to estimate HIV infection rates....

International HIV/AIDS trial finds continuous antiretroviral therapy superior to episodic therapy

The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), today announced that enrollment into a large international HIV/AIDS trial comparing continuous antiretroviral therapy with episodic drug treatment guided by levels of CD4+ cells has been stopped. Enrollment was stopped because those patients receiving episodic therapy had twice the...

Polymer aids in blood clotting, pointing way to new treatment

A serendipitous comparison prompted by an old scientific image and involving an ancient but understudied molecule may lead to a new treatment strategy for injuries or illnesses in which blood clotting is paramount to survival. . .. Polyphos...

Viral 'fitness' explains different resistance patterns to aids drugs

Some HIV medications lead to the development of drug-resistant HIV when patients take as few as two percent of their medications. For other medications, resistance occurs only when patients take most of their pills. These differences appear to be explained by the different levels of viral "fitness" of the drug-resistant HIV, say AIDS researchers in a new study. . .. Viral "fitness" refers to the...

AIDS drug from sunflowers

Sunflowers can produce a substance which prevents the AIDS pathogen HIV from reproducing, at least in cell cultures. This is the result of research carried out by scientists at the University of Bonn in cooperation with the caesar research centre. For several years now the hopes for a completely new group of AIDS drugs have been pinned to what is known as 'DCQA'. However, the substance is only av...

New licensing agreement to maximize AIDS drug development

Longtime collaborators CONRAD and the Biosyn Division of Cellegy Pharmaceuticals, Inc. today announced a non-exclusive licensing agreement to research and develop Biosyn-patented microbicides for the prevention of HIV and other sexually transmitted diseases. . The three microbicides covered under the agreement are in various stages of development and work under different mechanisms of action....

AIDS-related cognitive impairment exists in two separate forms

Cancer researchers are working toward a future in which each patient's tumor will act like a crystal ball, revealing how oncologists should treat the cancer to obtain the best outcome. . Currently, physicians cannot predict which patients with prostate cancer should receive extra therapy after surgery - or whether some of these patients have an indolent disease that does not even require surgery...

AIDS vaccine research offers new insights on survival

New insights into how a subpopulation of helper T-cells provides immunity and promotes survival following infection with an AIDS-like virus offer a new means of predicting an AIDS vaccine's effectiveness, a discovery that could help scientists as they test these vaccines in clinical trials. . .. "Over the...

Study defines effective microbicide design for HIV/AIDS prevention

Duke University biomedical engineers have developed a computer tool they say could lead to improvements in topical microbicides being developed for women to use to prevent infection by the virus that causes AIDS. . .. By applying fundamentals of physics and chemistry, the researchers developed a computer model that can predict the effectiveness of various microbicidal recipes in destroying human...

New study calculates millions of years saved in lives of AIDS patients

This year, the U.S. federal government will spend $21 billion for HIV/AIDS research, treatment, prevention, and related activities. Is this enormous expenditure paying off? A study published in the July 1 issue of The Journal of Infectious Diseases, now available online, indicates that it is--and more so than previously thought. . The study, by Rochelle P. Walensky, MD, MPH, Kenneth Freedberg , M...

Rhesus monkeys in Nepal may provide new alternative for HIV/AIDS research

Scientists investigating the genetic makeup of rhesus macaque monkeys, a key species used in biomedical research, have found the rhesus in Nepal may provide a suitable alternative to alleviate a critical shortage of laboratory animals used in work to develop vaccines against diseases such as HIV/AIDS. . Writing in the cover story of the current issue of the American Journal of Primatology, resea...
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