Customized gene chip provides rapid detection of genetic changes in children's cancer
... specific genetic abnormalities that influence the aggressiveness of neuroblastoma. An important abnormality is loss of heterozygosity (LOH), the deletion of one copy of a pair of genes. When the gene involved is a tumor suppressor gene, LOH removes a brake on uncontrolled cell growth, the growth that is the hallma...Targeted drug delivery achieved with nanoparticle-aptamer bioconjugates
...en diagnosed it is graded and staged to assess the aggressiveness of the tumour and how far it has spread, and for evaluating the type of treatment required. Treatment can involve surgery, radiotherapy, hormonal treatments and chemotherapy (severe cases). 3 Prostate cancer diagnosed at an early stage is usually tre...Researchers use 'trickery' to create immune response against melanoma
...en diagnosed it is graded and staged to assess the aggressiveness of the tumour and how far it has spread, and for evaluating the type of treatment required. Treatment can involve surgery, radiotherapy, hormonal treatments and chemotherapy (severe cases). 3 Prostate cancer diagnosed at an early stage is usually tre...Animal models show that anabolic steroids flip the adolescent brain's switch for aggression
...ked, bit and chased the intruders. In fact, their aggressiveness measured ten times greater than that of control ha...valent of half their adolescence. Eventually, the aggressiveness subsided; by three weeks of withdrawal, all the hamsters greeted intruders with normal, playful defe...A step forward in the fight against bacterial infections
...ntering our body, or it renders them harmless. The aggressiveness of the bacteria, our general state of health, and the speed with which our immune system reacts determine whether or not we become sick after contact with a bacterium. Upon contact with a bacterium, or a bacterial component, the immune system spring...Second opinion yields treatment changes for half of patients
...e in diagnosis, for other patients it affected the aggressiveness of their tumor. U-M established one of the first multidisciplinary breast care centers in 1985 to provide comprehensive diagnosis and treatment for women with benign or malignant disease. U-M currently has multidisciplinary clinics in 11 tumor ty...Changing length of days reverses how estrogen affects aggressiveness in mice
... that in some species estrogen plays a key role in aggressiveness as well." While this research has just begun, the findings could have broad implications in humans, for issues such as aggression and the role of estrogen in promoting cancer, Trainor said. Nelson and Trainer presented their results Oct. 18 in ...How mammals fuel milk production may have implications for cancer
...olism in tumors is associated with increased tumor aggressiveness and poor prognosis, the researchers said. “Our findings demonstrating a physiological requirement for Akt1 in the control of glucose and lipid metabolism further implicate Akt1 activation as a potential mediator of the Warburg effect and reinforce...Stress hormones may play new role in speeding up cancer growth
...l," he said. "MMP-2 and MMP-9 contribute to the aggressiveness of these tumors," Yang said. "It isn't clear exactly how they are operating but they may work with VEGF to facilitate blood vessel growth in new tumors so that they can grow." The target adrenergic receptors for these hormones are well-known to cl...Scientists find method to pick noncompetitive animals, improve production
.... In the latest research, the scientists show that aggressiveness and all other traits affecting social interactions are inherited and can be estimated. They also found that by using the new tool they were able to confirm two-thirds more inherited trait variations that impact social interactions than could be ident...