Mayo Clinic study finds two genes predict outcome for breast cancer patients
...rther research is needed to determine whether more aggressive or additional treatments will improve the outcomes of women identified to be at high risk by means of this marker." Breast cancer is diagnosed in approximately one million women each year, and claims the lives of over 40,000 in the United States. M...Cancer virus protein needed for successful infection
...velop adult T cell leukemia or lymphoma (ATLL), an aggressive disease characterized by a long latent period and the proliferation of T lymphocytes. The virus is spread by sexual activity, infected blood and breast milk. For this study, Lairmore and a group of collaborators developed a mutant strain of HTLV-1 ...Stem cell transplants improve recovery in animal models for stroke, cerebral palsy
...d." He hopes one day stem cell therapy, along with aggressive physical therapy and possibly tPA can work synergistically to reduce that disability. "These are not going to be cures, but this level of recovery is significant, and could help get somebody out of a bed and into a wheelchair or out of a wheelchair ...Sex chromosome genes influence aggression andmaternal behavior, say UVa researchers
...ltures and in most mammals, males are usually more aggressive and less nurturing than females. It's simple to bl...nes may not be the whole story that determines how aggressive or motherly we are, but they are a partof it." Rissman's work is published in the Feb. 22 issue of ...Molecular force field helps cancer cells defend against attack
... pump out high volumes of FAK and VEGFR-3 are more aggressive tumors, Cance said. The scientists were able to block FAK from binding with VEGFR-3 by introducing a different protein that stopped cancer cells from dividing and caused them to die but spared normal breast cells. "FAK is a critical molecule, and in...Scientists discover new genetic subtypes of common blood cancer
...ns in an individual patient might help predict how aggressive the disease would be. For this deeper analysis, the researchers created an algorithm based on a recently developed computational method designed to recognize individuals by facial features. It is called non-negative matrix factorization, or NMF. In ...It's in the genes: Study opens door to new treatment of the blues
...elop the aversion despite repeated encounters with aggressive rodents. The study will be published in the Feb. 1...daily bouts of social threats and subordination by aggressive rodents and continuous sensory contact with the aggressors for 10 days. Afterward, the defeated mice...World shark attacks dipped in 2005, part of long-term trend
Assertive and even aggressive human behavior could explain why shark attacks worldwide dipped last year, continuing a five-year downward trend in close encounters with the oceanic predators, new University of Florida research suggests. Greater safety precautions and in-your-face...Patients now surviving once-fatal immune disease
...ing proteins called antibodies. Treatment includes aggressive use of antibiotics and replacement of the missing antibodies with gamma globulin. "Almost all of the adults with XLA had chronic medical problems; however, these problems did not interfere with normal daily activities, and the quality of life in thi...How 'hot' emotional brain interferes with 'cool' processing
...ters -- emotional images such as injured people or aggressive behavior; neutral images such as people shopping or working; and scrambled images that meant nothing. The subjects were then showed a face image and asked to determine whether it was one of the original "to-be-memorized" faces or a new face. Through...New cellular flaw found in some virulent breast cancers
...molecular interaction that triggers a particularly aggressive form of breast cancer, and suggest that attacking ... CDK4 as a targeted approach to treating this very aggressive cancer." Breast cancers composed of cells that contain both the overactive cyclin D1-CDK4 switch an...Viral protein helps infected T cells stick to uninfected cells
...velop adult T cell leukemia or lymphoma (ATLL), an aggressive disease characterized by a long latent period and the proliferation of T cells. The infected cells are spread from person to person during sexual activity and by blood and breast milk. In the body, the HTLV-1 mainly targets immune-system cells know...Aggression-related gene weakens brain's impulse control circuits
...is gene variant biases the brain toward impulsive, aggressive behavior." The gene is one of two common versions that code for the enzyme monoamine oxydase-A (MAO-A), which breaks down key mood-regulating chemical messengers, most notably serotonin. The previously identified violence-related, or L, version, co...Invasive species harms native hardwoods by killing soil fungus
...es cause little harm, while others can become very aggressive and radically transfigure their new habitat. "The mechanisms for this phenomenon and its potential long term impacts remain poorly understood," Stinson adds, "but one possibility is that invasive species may disrupt fragile ecological relationships ...Hyena mothers give their cubs a helpful dose of hormones
... hormones that make her budding young leaders more aggressive and sexually advanced. The report, published in t...sequently, the cubs of the alpha females were more aggressive and exhibited more sexual play, characteristics that elevate the chances for life-success in both se...Canine cancer vaccine program shows early promise
...lent of one form of skin cancer in humans, is very aggressive in dogs. It usually manifests itself in or around the mouth or toes. Despite conventional treatment, 75 percent of dogs with oral melanoma will die within one year. But about 40 percent of dogs with a melanoma tumor present responded to a vaccine ...Animal models show that anabolic steroids flip the adolescent brain's switch for aggression
..., vasopressin levels subsided in parallel with the aggressive behavior. The anterior hypothalamus regulates agg...hope these new insights can lead to treatments for aggressive behavior, with or without steroid abuse. "Linking aggression to fluctuations in vasopressin makes i...Combination therapy improves AIDS-related lymphoma outcome
Combining aggressive HIV therapy and chemotherapy significantly improve...e greatest benefit for HIV patients suffering from aggressive malignant non-Hodgkin's lymphoma. This benefit was most pronounced in HIV patients without severely ......at glioblastoma multiforme (GBM). This is the most aggressive form of brain tumour, growing very quickly before symptoms are experienced and killing most patients within a year of diagnosis. Working in mice, Alexander Levitzki and colleagues (of The Hebrew University of Jerusalem and Ludwig-Maximilians-Univer......s a new tool to better diagnose breast cancer. The aggressive disease claims the lives of more than 40,000 American women each year -- so a diagnostic tool that will allow patients to begin a course of treatment as early as possible is urgently needed. Meyer-Baese hopes to utilize magnetic resonance imaging (M...