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Tag: "aggressive" at biology news

Pair of microRNA molecules controls major oncogene in most common leukemia

...pression of the TCL1 oncogene that drives the most aggressive forms of the leukemia, said the study’s lead autho... miR-29 and miR-181 is associated with a much more aggressive cancer." Drugs that boost production of these two natural TCL1 inhibitors might work as a future ...

Changing length of days reverses how estrogen affects aggressiveness in mice

...drug halting estrogen production made the normally aggressive mice less aggressive. In mice kept in long day len...begin to explain why estrogen could make mice more aggressive in winter, and less aggressive in summer. To investigate whether this theory was true, Nelson and...

Fruit fly aggression studies have relevance to humans, animals

...tions. From each generation, she selected the most aggressive flies from the high aggression group, the least aggressive flies from the low aggression group, and a random sample of the control flies, to be the parents of ...

Cancer stem cells linked to radiation resistance

...st deadly form of brain cancer worldwide. Although aggressive treatments can destroy the majority of the cancerous cells, a small fraction of them remain and often regenerate into even larger masses of tumor cells. Until recently, scientists knew little about what made these resistant cells different from th...

Breastfeeding boosts mental health

...astfed had particularly lower rates of delinquent, aggressive and anti-social behaviour, and overall were less depressed, anxious or withdrawn. "These results are powerful evidence for more support to be given to mothers to help them breastfeed for longer," she said....

Scientists use gene signatures to match cancer and other diseases with potentially effective drugs

...eceptor in prostate cancer cells that drives their aggressive growth. Dana-Farber researcher Haley Hieronymus, PhD, who used the Connectivity Map to sift through thousands of drugs and compounds, is the paper's lead author. The researchers said that in view of these promising results, they are proposing a lar...

How the US drug safety system should be changed

...ring and proposes a solution that addresses overly aggressive early marketing practices; an absence of incentives to complete post-marketing safety studies; direct-to-consumer (DTC) advertising that can promote non-critical use of "blockbuster" drugs; the current trend toward delaying drug approval; and public ...

Do angry men get noticed?

...males, with males being larger and more physically aggressive than females, one might also suspect differences in the way in which threat is detected from individuals of different genders. In the new work, Williams and Mattingley show that angry male faces are found more rapidly than angry female faces by bot...

'Molecular assassin' targets disease gene

...?in any number of areas involving inflammation and aggressive vascular growth. "Our experimental drug, Dz13, is like a secret agent that finds its target, c-Jun, within the cell and destroys it," he said. "It is a specific, pre-programmed 'molecular assassin'." The paper in Nature Biotechnology shows the pot...

The higher the hierarchy, the greater the aggression

...on) investigate the extent to which differences in aggressive behavior within a cooperative society can be expla...tablish their status. "We found that rates of both aggressive 'displays' (aimed at individuals of lower rank) and aggressive 'tests' (aimed at individuals of high...

Immune system police learn early and sometimes badly

...y are exposed to in the body. In fact T cells most aggressive at attacking endogenous tissue likely would be among those converting to protective regulatory cells, Dr. Ignatowicz says. "We did not find that does not happen, but it's not the major mechanism for generating regulatory cells in the body," Dr. Pach...

First-ever genomic test predicts which lung cancer patients need chemotherapy to live

...patients from the 'no chemotherapy' group into the aggressive treatment group." The researchers will publish t...scribed only to patients with relatively large and aggressive tumors. Early-stage patients ?those with small, stationary tumors ?are considered at low risk of r...

New egg freezing technique offers hope to hundreds of women

...servation of fertility in women who are in need of aggressive treatment for malignant diseases." ...

Breast stem cells have features similar to 'basal' tumors

The most aggressive form of breast cancer may originate from breast st...se and otherfeatures of the stem cell resemble the aggressive 'basal' subtype of breast cancer. There is increasing evidence that breast cancer is not simply a si...

Possible birthplace of malignant brain tumors identified

...said suggests a possible treatment for the lethal, aggressive brain tumors called malignant gliomas. Arturo Alvarez-Buylla and Erica L. Jackson, of the University of California, San Francisco, and colleagues reported their findings in a paper in the July 20, 2006, Neuron, published by Cell Press. In their stu...

Survivors of childhood polio do well decades later as they age

...er researchers have suggested that polio is a more aggressive condition later in life, but we've actually found it to be relatively benign," says Eric Sorenson, M.D., Mayo Clinic neurologist and lead study researcher. "Our results suggest that polio survivors may not age any differently than those in the normal...

Friendly bacteria in chewing gum that bites back

...icks to the surface of teeth, where it produces an aggressive acid that breaks down the enamel. The friendly bugs in the gum will make the S. Mutans clump together, preventing them from becoming attached to the tooth surface. Tests reveal that the chewing gum can reduce the amount of bacteria in the mouth fifty...

'Signature' of chromosome instability predicts cancer outcomes

... and grade 2 breast cancer, distinguished the more aggressive cancers within each grade. ...

Speeding discovery of the 'human cancer genome'

...cer, "how specific lesions interact to produce its aggressive characteristics remains poorly understood." Lowe's team relied on mice with specific pathological changes known to play a role in some liver cancers. They then searched for other spontaneous mutations in the animals' tumors and compared them to re...

Malignant melanoma cells secrete protein required for embryo formation

...tern University research group has discovered that aggressive melanoma cells secrete Nodal, a protein that is cr...ghly unstable embryonic growth factor by injecting aggressive melanoma cells into developing zebrafish embryos, which were used as "biosensors" for tumor cell-der...

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