Tag: "agents" at biology news

Scratch no more: Gene for itch sensation discovered

.... So now researchers can study the effect of these agents on the itch sensation and possibly move that research to clinical applications fairly soon."...

Agent slows aging in mice

...will test as many as two dozen possible anti-aging agents in animals in the next five years. The other centers are the University of Texas Health Science Center in San Antonio, Texas, and the Jackson Laboratory in Bar Harbor, Maine. The scientists were surprised to find so quickly that one agent showed p...

Cells re-energize to come back from the brink of death

...normal cells were exposed to cancer drugs or other agents that triggered apoptosis. The researchers then blocked apoptosis in order to study CICD. “The GAPDH response appears to represent a basic, reproducible event. But in order to verify that hypothesis, we’ll need to study it in the body, especially as w...

CSIRO scientists join fight to save 'Tassie devil'

...g establishing whether a virus or other infectious agents are associated with the tumours,” AAHL’s Dr Alex Hyatt said. “If successful, the establishment of pre-clinical tests will allow researchers to remove known infected devils, in turn limiting the spread of the disease.” To date AAHL scientists have ...

Largest synthetic gene ever built offers insights into anti-malarial drug resistance

...ow the parasite escapes destruction by most of the agents now used against it, he said., When a malaria parasite is transmitted through a mosquito bite, the mosquito injects the parasite into skin or blood, which then travels to the liver within minutes, grows and divides there, and then ruptures liver...

Studies to find better ways to preserve human eggs, ovarian tissue under way

...that can be used safely in higher doses as well as agents to help protect tissue during the ultra-rapid proc...ntrations, you cannot get true vitrification.” The agents are needed to intercept water so it won’t form ice. Interestingly if small ice crystals form during ...

In mice, drug protects against diabetes and atherosclerosis

...2 "can lead to a new class of powerful therapeutic agents to prevent and treat metabolic diseases such as type 2 diabetes and atherosclerosis." Said Hotamisligil, "This work turned out to be a perfect example of out-of-the box thinking, inter-institutional and inter-disciplinary science, to bridge discov...

Newly found sensing system enables certain bacteria to resist human immune defenses

...ermidis is one of several hard-to-treat infectious agents that can be transmitted to patients in hospitals v...well-known types of gram-positive bacteria include agents that cause anthrax, strep throat, flesh-eating disease and various types of food poisoning. In gr...

Brightening prospects of using fluorescent nanotubes in medical applications

...ake them particularly suitable for use as contrast agents in cells and tissues,” says Tobias Hertel, the associate professor of physics who headed the research. “Now that we know how to separate out the brightest ones, I hope that researchers will begin considering ways to use them in clinical applications....

Researchers shed light on mechanism of action used by anti-cancer drug

...ich it is combined with other molecularly targeted agents for patients with blood cancers and solid tumors. ...nt might be logically combined with other targeted agents whose antitumor activity is limited by Mcl-1 expression,” Grant said. Several such targeted agents a...

Genetic factors are linked to fever following smallpox vaccination

...er live vaccines. Immunization against infectious agents has been one of the greatest successes of modern medicine, and the eradication of smallpox from the world is considered by some to be the crowning event of the 20th century. However, immunization with live virus particles, as in the smallpox vaccine,...

Could fungal collection hold the key to new life-saving drugs?

...ts, antibiotics such as penicillin, lipid lowering agents and anti-fungal drugs....

Gene therapy study shows safety and statistically significant improvement in Parkinson's disease

...latform to translate a variety of new gene therapy agents into human clinical trials for many devastating brain disorders,” said Paul Greengard, PhD, chairman of the Neurologix Scientific Advisory Board and recipient of the 2000 Nobel Prize for Physiology or Medicine for his work related to how brain cells ...

Cytomegalovirus exacerbates atherosclerosis through an autoimmune mechanism

...risk factors. Recently inflammation and infectious agents have been shown to play an important role in the onset of acute cardiovascular events. The online, open-access PLoS ONE publishes a new study on the relationship between Cytomegalovirus infection and atherosclerosis, conducted by Prof. Roberto C...

Detecting cold, feeling pain: Study reveals why menthol feels fresh

...hat the receptor was activated by chemical cooling agents such as menthol, a natural product of mint, and co...n known for years that menthol and related cooling agents evoke the psychophysical sensation of cold – somehow by interacting with the aspect of the sensory n...

Better insight into brain anatomical structures

...aling anatomical details of soft tissues. Contrast agents can help to make these images even clearer and allow physiological processes to be followed in real time. Conventional gadolinium complexes currently used as MRI contrast agent cannot reveal anatomic structures. As reported in the journal Angewandte ...

Resistant HIV quickly hides in infants' cells

...mission but also development of new antiretroviral agents for pediatric use, particularly against highly resistant infection. "There is also a need for new and widely accessible methods for detecting HIV infection in infants, whether resistant or not," he pointed out, "since transplacental transfer of mater...

Early exposure to indoor fungus molecules may protect infants against future allergies

...s (natural compounds secreted from disease-causing agents like bacteria) in 574 infants, enrolled in the Cincinnati Childhood Allergy and Air Pollution Study (CCAAPS), who were identified as being at greater risk for future allergies because at least one parent had known allergies. The CCAAPS, funded by ...

Catching cancer's spread by watching hemoglobin

... MRI resolution) and does not require any contrast agents or fluorescent markers (unlike most other high-resolution vessel-imaging techniques). Clinically, the imaging technique can potentially be used to detect the spread of cancer, since angiogenesis—the growth of new blood vessels from existing ones...

pHLIP, a novel technology to locate and treat tumors

...hey expect that by attaching and delivering active agents with pHLIP, that tumors may be able to be treated. Targeting is based on the fact that most tumors, even very small ones, are acidic as a result of the way they grow. “Since the mechanism is general, and since even very small tumors can be target...

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