Creating new life forms that may help eradicate cancer affecting women
...ia vaccines harness the power of the immune system against this infectious agent," explains Dr. Shabahi, "and then directs it to successfully attack cancer cells. The bacterium in effect then becomes a cancer-fighting 'Trojan horse,' with the enemy tucked inside." For breast cancer, Dr. Shababi's team f...Drug treatment improves learning in mice with Down syndrome symptoms, Stanford/Packard study shows
... and Fernandez both strongly cautioned individuals against experimenting with the compound or others like it on their own. Appropriate doses and schedules have not yet been determined for humans, and the purity and safety of similar over-the-counter concoctions are questionable. Finally, they emphasized that...Vaccine to cope with viral diversity in HIV
...s. These immunogens should elicit immune responses against high frequency viral strains as well as against most mutant forms of the virus. ...Fruit flies and global warming -- Some like it hot
...l amount of heat exposure really toughens flies up against a heat wave, but they don't do quite as well when things are cooler." This means that heat hardening is really important in climates where there are hot days over 37 Celsius in summer, but there's not much benefit when it's always warm or always cool...MIT's ocean model precisely mimics microbes' life cycles
...ild of oceanographer Mick Follows, has been tested against real-world patterns of a particular species of phytoplankton, called prochlorococcus, which dominates the plant life of some ocean regions. Follows and co-authors report this work, part of the MIT Earth System Initiative's new Darwin Project, in ...100 percent juices found as beneficial to health as fruits and vegetables
...paper “Can pure fruit and vegetable juices protect against cancer and cardiovascular disease, too? A review of the evidence?suggest that more studies in certain area are needed to bolster their findings. The study was published in the International Journal of Food Science and Nutrition (2006). “Although...Novel laboratory technique nudges genes into activity
...orey said. "We’re working with nature, rather than against it." Drs. Corey’s and Janowski’s current results are built on previous work, published in 2005 in Nature Chemical Biology, in which they found that RNA strands could turn off gene expression at the chromosome level. The new UT Southwestern res...Biologists call for better choice of model organisms in 'evo-devo'
...r developmental similarities to it. "We caution against this widely used rule of thumb, and advise the use of additional criteria, such as molecular branch lengths, to choose species as best representatives of ancestral body plans," said Dr Jenner. "Just because an organism has sprung from the base of ...New UD technology removes viruses from drinking water
...lutants in groundwater, but no one had tested iron against biological agents," Chiu said. So the two research...as been documenting the technology's effectiveness against human pathogens including E. coli 0157:H7, hepatitis A, norovirus and rotavirus. Rotavirus is the nu...Cancer cells forming blood vessels send their copper to the edge
...ambling for ways to stop angiogenesis in the fight against cancer. One element critical to blood vessel growth is copper, a vital nutrient that plays important roles in many life processes. Compounds that reduce copper in the body without disrupting the body's normal functions can inhibit the growth of bl...MIT bioengineer advances survival, promise of adult stem cells
... cells. However, its ability to protect stem cells against the sort of pro-death signals found at the implant site was previously unknown. When EGF attaches to receptors on the stem cell surface, it activates many pathways that can influence stem cell proliferation, migration and differentiation. However,...Research project tackles 'regeneration' gap
...e body’s own supply of adult stem cells to protect against or fight Alzheimer’s and Parkinson’s diseases, cancer, multiple sclerosis and traumatic injury. The project has received support from two private gifts ?from Jon and Beverly Thompson of Sanibel, Fla., and from the Thomas H. Maren Foundation, based...Widely used hepatitis B drug spurs HIV drug resistance
...nt from any other that has been shown to be active against HIV - it breeds resistance rapidly, despite its ability to reduce the amount of HIV in the body," says senior study author and infectious disease specialist Chloe Thio, M.D. Researchers say the findings, to be presented Feb. 28 at the 2007 Confere...Temple University Hospital investigates treatment for cervical dysplasia
...g to Hernandez, HPV vaccines have shown protection against certain high-risk strains that cause approximately 55 percent of high-grade cervical dysplasia and 70 percent of cervical cancer cases. "The vaccines do not eliminate the risk of developing cervical cancer," said Hernandez. " They do not provide pro...... neuroscientists, calling this a possible strategy against stroke, Alzheimer's and other neurodegenerative diseases. Lead author Michel Baudry of the University of Southern California, his graduate student Wei Xu and collaborators from the University of British Columbia outline their technique in the Feb. 1...It's in your head: The brain's own globin defends you from shock and stroke
... to oxygen deprivation and plays a protective role against brain damage. Structurally similar to hemoglobin (blood) and myoglobin (skeletal muscle), neuroglobin is found in neurons and is most prevalent in areas of the brain that have adapted to physiological stress, such as stroke. Unlike hemoglobin or myog...White blood cells of cancer-resistant mice overwhelm natural defenses of cancer cells
... "Each cell type had independent killing activity against the cancer cells," the authors said, using different molecules. Macrophages, for instance, have to be in physical contact with the cancer cell before unleashing its combination of killer molecules. White blood cells from the cancer-resistant mice a...St. Jude announces breakthrough in eye cancer treatment
...e Pharmaceuticals (Nutley, N.J.) for a similar use against a related target called MDM2 in adult cancer cells. The success in knocking out MDMX with nutlin-3 represents the first example of local delivery of a targeted chemotherapy drug for any childhood cancer, Dyer said. Targeted therapy uses a customiz...Single molecule extends fat mice lives by reversing gene pathways associated with disease in obese
...ost 60 percent. It has also been shown to protect against Huntington's disease in two different animal models (worms and mice). "The "healthspan" benefits we saw in the obese mice treated with resveratrol, such as increased insulin sensitivity, decreased glucose levels, healthier heart and liver tissues, ...... it is not toxic." Siomycin A must now be tested against other cell lines in the laboratory and in preliminary animal experiments before human trials could be planned. Only a tiny fraction of promising candidate drugs enter clinical trials, and few of those are ever approved. Gartel said the participatio...