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Tag: "against" at biology news

Genes and biomarkers that allow doctors to choose the right therapy for the right patient

...mbined with radiation therapy, is indeed effective against lung or brain cancer. "It is difficult to assess the response of cancer in the brain or lung to treatment, since those neoplasms are difficult to access safely," said Roberto Diaz, M.D., Ph.D., a resident in Radiation Oncology at the Vanderbilt-...

FSU researchers determine a critical factor in workings of proteins

... processes, such as the utilization of and defense against toxins; the activation of receptor proteins on cell membranes by growth hormones; and the regulation of actin polymerization, which influences the physical structure of living cells. The association rate thus plays a critical role in the overall heal...

Researchers find hepatitis A and hepatitis C attack same protein to block immune defenses

...titis C’s chronic nature and the lack of a vaccine against it. But while better sanitation has driven a decline in hepatitis A cases in the United States, Lemon said, "It’s a significant risk for many people traveling overseas, because they fail to receive the vaccine." Hepatitis A has also been the cause of...

New research shows that flu is a trigger of heart attacks

...that a number of new vaccines were being developed against avian flu virus (the most likely cause of the next flu pandemic), "In addition, we are rapidly stockpiling antiviral drugs (such as Tamiflu), so I think we are likely to have the means of preventing or combating the virus, if nature doesn’t take us b...

HIV protein enlisted to help kill cancer cells

...th. Hawkins wondered if TAT-Bim could be effective against cancer, and a productive scientific collaboration began between their labs to exploit the anticancer potential of TAT-Bim. "Unlike most healthy cells, cancer cells grow very fast. So they are always on the verge of running out of natural ingredient...

Trojan horse strategy defeats drug-resistant bacteria

...ant to antibiotics, and existing drugs work poorly against chronic infections like those that occur in wounds...xist in the human body. Gallium was even effective against strains of Pseudomonas aeruginosa from cystic fibrosis patients that were resistant to multiple anti...

Producing medicines in plant seeds

... whole human antibodies in protecting animal cells against infection with the Hepatitis A virus. This is a significant step forward in making protein production in plants a real alternative to current production methods....

Penn study on lung-infecting bacterial enzyme suggests new approach to cystic fibrosis treatment

... new paradigm for treating CF. Specific inhibitors against the enzyme, in conjunction with current antibiotic...he research team is to develop specific inhibitors against the bacterial SMase and test the idea in an animal model. ...

New research says winning a Nobel Prize adds nearly 2 years to your lifespan

...y made control group they can be directly measured against - scientists who were nominated for a Nobel prize but did not actually win one. The researchers looked at winners and nominees in physics and chemistry between 1901 and 1950 (the full list of nominees are kept secret for 50 years). This gave them ...

Antivirals effectively curb influenza virus

...an. "While the efficacy of antivirals to protect against influenza is critical, the effect of these drugs o...chers found that both drugs were highly preventive against influenza illness, with oseltamivir at 81 percent efficacy and zanamivir at 75 percent. Thus, the pr...

Researchers discover surprising drug that blocks malaria

...needed because the parasite has evolved resistance against virtually all types of commonly used drugs," said ...aria were expected in 2006. Commonly used drugs against malaria attack the parasite, but it rapidly changes its molecular structure to become resistant to t...

Cancer researchers add spice to research against rare neuromuscular disease

...ncer have discovered a compound that shows promise against a debilitating neurodegenerative condition known a...to the test, finding that the spice offers promise against breast cancer, melanoma, Alzheimer's disease and the blisters that come with radiation treatments fo...

Discovery of an HIV inhibitor in human blood points to new drug class

...development of another class of drugs in the fight against the pandemic disease, researchers reported in the ...tude. VIRIP and its derivatives remained effective against drug-resistant HIV strains, making them "highly promising for further clinical development," accordi...

Protein found to shield pancreatic cancer cells from self-destruction

...elves, removing one of the body's natural defenses against out-of-control cell growth, researchers at The University of Texas M. D. Anderson Cancer Center report in the March issue of Molecular Cancer Research. The protein tissue transglutaminase, known by the abbreviation TG2, previously has been found by ...

Scientists uncover new target in cancer mutation puzzle

...ow they might lead to a promising way to intervene against cancer. "We have very little understanding of how Ras and p53 or any other potent gene mutations cooperate to cause malignant tumors," said Land, who is professor and chair of the Department of Biomedical Genetics and scientific director of the J...

Long-lived deep-sea fishes imperiled by technology, overfishing

...m one seamount end up populating another. The odds against these fish are so high that, in a reproductive sense, they have to wait for the stars to align before they successfully produce offspring that will survive until maturity." Natural and human-influenced climate factors including El Niño, the Pacifi...

RNAi shows promise in gene therapy, Stanford researcher says

...ases. "We've worked on a gene therapeutic approach against viral hepatitis for about 10 years and this is the first thing we've done that really looks promising," said Kay, professor of genetics and of pediatrics at the Stanford University School of Medicine. Kay will talk about future uses for RNAi ge...

Knocking out survival protein could aid leukemia treatment

... drugs might also offer an effective one-two punch against drug-resistant forms of chronic lymphocytic leukem...Mcl1 may be an effective target for drugs directed against CLL and ALL," says principal investigator John C. Byrd, professor of internal medicine and director ...

New research may overturn conventional wisdom on drug-resistant tuberculosis

...w strain that is already drug-resistant, sometimes against multiple drugs. The authors of the new study, Qian Gao, PhD, and coworkers in Shanghai, China and elsewhere, used molecular genetics and drug susceptibility testing to investigate patients with TB who were treated in Shanghai hospitals during 199...

Will the plague pathogen become resistant to antibiotics?

...The ability to resist many of the antibiotics used against plague has been found so far in only a single case of the disease in Madagascar. But because the same ability is present in other kinds of bacteria from a broad range of livestock, antibiotic resistance could potentially spread to other Y. pestis and...

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