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Tag: "against" at biology news

Scientists learn the origin of rogue B cells

...dered why, in some people, the immune system turns against parts of the body it is designed to protect, leadi...dy's mechanism to correct them. "Our research goes against the theory that B cells should only express a single receptor," says Casellas. Using a technique ...

Bacterial walls come tumbling down

...will accelerate the search for an effective weapon against the infamous superbug. The images produced by Strynadka's team show the enzyme frozen in place by a powerful antibiotic called moenomycin. Moenomycin has been used for decades in animal feed to promote livestock growth. Bacteria have shown very li...

NIAID DNA vaccine for H5N1 avian influenza enters human trial

...human cells to make proteins that act as a vaccine against the virus. VRC Director Gary Nabel, M.D., Ph.D...the potential for employing new vaccine technology against influenza, a disease for which effective vaccines have long been made, but for which the reliability...

Hybrid molecule causes cancer cells to self-destruct

...l partner, it can deliver a powerful double-whammy against cancer cells." Sampathkumar and his colleagues... carrier but as additional ammunition in the fight against cancer." The researchers focused on a sugar called N-acetyl-D-mannosamine, or ManNAc, for short. ...

Fighting influenza & co. with 40,000 blood samples

...samples of older patients which are less effective against these pathogens than in the case of younger patients.' The Dutch project partner, the Academic Medical Center in Amsterdam, discovered the coronavirus NL63. This virus belongs to the same group as the SARS virus, which gained notoriety during an e...

Breakthrough vaccine to treat chemo-resistant ovarian cancer

...ne priority is to help our patients win the battle against cancer," said Dr. Edgar Staren, Chief Medical Offi...py represents a promising new chapter in the fight against this devastating disease and brings hope to women everywhere." The breakthrough treatment method ...

Stem cells act through multiple mechanisms to benefit mice with neurodegenerative disease

...ed the first "multidisciplinary" use of stem cells against a degenerative disease, but also highlighted the fact that, in the future, the most successful therapies - including those employing stem cells -- will likely invoke the use of multiple strategies in concert. Indeed, the stem cell may be the "glue" t...

Synthetic peptide targets latent papilloma virus infections

...higher organisms, says that such a drug might work against all strains of HPV because the E2 tethering protei...s used to block HPV spread might also prove useful against other infectious viruses, such as the related Epstein-Barr virus, the cause of mononucleosis and an ...

A genetic 'gang of 4' drives spread of breast cancer

...flammatory, and is being tested in clinical trials against many types of cancer. The researchers also tested whether cetuximab and celecoxib would work effectively in concert to reduce metastasis in mice. "We found that the combination of these two inhibitory drugs was effective, even though the drugs indi...

Africa's first large-scale HIV vaccine study launches

...based on clade B HIV, has the potential to protect against the clade C virus, the subtype prevalent in South ...be safe and to stimulate cellular immune responses against HIV in more than half of volunteers. Merck Research Laboratories developed the test vaccine that i...

Chlamydia vaccine a step closer to reality

... developing a world-first vaccine to protect women against contracting the most common sexually-transmitted d...ntified certain proteins that were able to protect against Chlamydia infection. "We've been testing these proteins as part of animal trials...and we think w...

Anthrax attack posed greater potential threat than thought

...cs and vaccination appeared to be highly effective against the disease. In October of 2001, a letter contain...d; and, for comparison, six individuals vaccinated against B. anthracis, two confirmed to have had anthrax, and 12 with no known B. anthracis exposure. The ...

Cold sore virus might play role in Alzheimer's disease

...her possibility is that the body's immune response against herpes somehow damages the brain, and that such damage is worse in people with the ApoE-4 copy of the gene. Earlier this year Federoff's team published a study that showed inflammation is the earliest change that could be detected in a brain affected...

Protein fragments sequenced in 68 million-year-old Tyrannosaurus rex

... He also tested mastodon bone, sent by Schweitzer, against a database of existing amino acid sequences and against a set of mastodon theoretical sequences. He identified a total of 78 peptides, including four unique...

Cancer-killing invention also harvests stem cells

... decoy receptors, giving them a natural protection against TRAIL, whereas cancer cells mainly express the two receptors that signal cell death. During the death of the cancer cells, TRAIL is not depleted or used up in any way, and in fact, it stays active for many weeks or months. The same TRAIL molecul...

Antifungal drug kills TB bug

...ever a limited number of drugs that were effective against TB anyway," said Professor Munro, who is based in the University’s £38 million Manchester Interdisciplinary Biocentre. "People in places like India or Africa would be given antibiotics but often not in sufficient quantities to kill the bug complet...

In-shell vaccine for chick disease

...s are now developing a new way to vaccinate chicks against the disease ?one that can be delivered while they are still in their egg. A pre-hatching prototype vaccine virus which provides immunity to IBV has been developed by scientists at the Institute for Animal Health (IAH) and vaccine company Intervet U...

New protein inhibitor impedes growth of cancerous cells

... identified as acting specifically and effectively against one particular cell-division kinase, known as Plk1. In the new work, Steegmaier et al. isolated a chemical compound, which they term BI 2536, that they demonstrate to be a potent inhibitor of Plk1, and show that BI 2536 can indeed effectively halt...

Antibody therapy prevents type 1 diabetes in mice

... prone to developing the disease using an antibody against a receptor on the surface of immune T-cells. Accor...d other foreign substances in the body -- directed against a receptor known as CD137 on the surface of a type of immune cell called T-cells. Treating NOD mice ...

Research on grey mould offers possible breakthrough in tomato cultivation

... tomato varieties without having to use pesticides against grey mould (Botrytis cinerea). This is the conclus...as were found that accommodated resistance factors against grey mould. DNA-markers were then developed for each area to be able to track the presence of each r...

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