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Tag: "again" at biology news

Common molecular 'signature' identified in solid tumors

...argets. Finding the ones that appear over and over again in various forms of cancer will help us design new and better interventions," says Croce. MiRNAs can behave like oncogenes, which promote tumor growth, or tumor suppressors, which keep potentially malignant cells in check. Croce points out that miR...

Study finds 60 new genes controlled by DNA snippet

... of billions of cells, DNA must be read and copied again and again to supply each cell with its needed copy. Over time, random changes, or mutations, are inserted into...

US woman gives birth to baby from world's first frozen donor egg bank

... 6 months, and only after the donor tests negative again for HIV and other infectious diseases are the eggs released for sale. Several of the founders of CEI have both professional and personal experience with infertility. Diana Thomas, CEO, had her own three children with donor eggs, and based on that ex...

Report lists top 20 most-vulnerable African carnivores

...erous immortality. "Getting telomeres replicated again is required for carcinogenesis to proceed," Cech explained. "It's an essential step in the development of cancer, and that makes it of a lot of interest therapeutically, because it is a target that could impact a wide variety of cancers." Telomeras...

Groovy protein essential for promoting cancer development

...erous immortality. "Getting telomeres replicated again is required for carcinogenesis to proceed," Cech explained. "It's an essential step in the development of cancer, and that makes it of a lot of interest therapeutically, because it is a target that could impact a wide variety of cancers." Telomeras...

Hopkins researchers discover genetic switch that turns off an oxygen-poor cell's combustion engine

... absence of the HIF-1 gene. The hypoxic cells once again accelerated glycolysis and produced increased amounts of ATP; and with the PDK forced to work, the cells were also able to shut down the TCA cycle. This showed that PDK is the protein activated by HIF-1 to prevent the mitochondrion from producing ROS...

'Dead zone' summer killed billions of ocean state mussels

...ened in Narragansett Bay in the summer of 2001 and again in the summer of 2003. Mussels, however, can help control nutrient overload and hypoxia by consuming phytoplankton, which reduces bottom-dwelling bacteria. "When we lose mussels, we may be losing the ability to prevent future dead zones from forming...

U-M researchers take new approach to defeating Gram-negative bugs

...ifferent growth conditions, the cell began to grow again but without the hair-like structure. The cells survived---but they looked a lot like Gram-positive cells, without all the sugars on the outside. "We, as well as the entire scientific community, always thought Gram-positive cells could not survive ...

Relationship of brain and skull more than just packaging

...d to find locations that could be accurately found again and again. Locating reliable markers was easier on the rigid skull than on the brain. Co-author of the paper, Kristina Aldridge, former postdoctoral researcher at Penn State and now at Washington University, looked at the reproducibility of standard ...

MiRNA fingerprint identified in platelet formation

...L lines, they found that 10 miRNAs were turned on, again representing a molecular signature for that disease. "Interestingly, half of that number are also members of the miRNA profile in normal platelet cell development ?suggesting that this small subset may be most important in understanding how AMKL deve...

Weizmann Institute suggests that immune cells help to maintain cognition and brain cell renewal

...he important immune cells except for T cells, they again found impairment of brain-cell renewal, confirming that the missing T cells were an essential requirement for neurogenesis. They observed that the specific T cells that are helping the formation of new neurons are the ones recognizing CNS proteins. ...

Clock molecule's sensitivity to lithium sheds light on bipolar disorder

...these clock genes cause Rev-erb to increase, which again inhibits bmal and clock. "The time it takes for that to happen determines the length of the cycle–roughly 24 hours–and keeps the clock going," explains Lazar. Penn colleague and coauthor Peter Klein, MD, PhD, Assistant Professor of Medicine, discove...

UC Berkeley researchers create a biologically-inspired artificial compound eye

...compound-eye mold that could be used over and over again using soft lithography technology, a set of methods developed over the last decade to replicate nanoscale-sized structures. The material they chose for the artificial eyes was an epoxy resin that cures into a hardened form when exposed to ultraviole...

Stem cell mobilization therapy appears to be ineffective in repairing damage caused by heart attack

..., no increase in the risk of restenosis (narrowing again of an artery after treatment) or major adverse cardiac events was observed with G-CSF treatment," the authors write. "The REVIVAL-2 trial had a cohort that was larger than all 3 previous trials taken together and had a relatively long follow-up peri...

Common molecular 'signature' identified in solid tumors

...argets. Finding the ones that appear over and over again in various forms of cancer will help us design new and better interventions," says Croce. MiRNAs can behave like oncogenes, which promote tumor growth, or tumor suppressors, which keep potentially malignant cells in check. Croce points out that miR...

Picking particles faster than one at a time

...ons were false positives, when the program was run again -- using a template after segmentation to filter out incompatible shapes -- false positives dropped to a mere 7 percent. Beyond the demonstrated goal of selecting the same particles an expert would select with a low error rate, future refinement of...

New U. of Colorado at Boulder flu chip may help combat future epidemics, pandemics

...s more than 90 percent accurate and will be tested again "side by side" with standard flu-virus culturing methods for accuracy and speed at the CDC's Atlanta headquarters next month. "This was the first time a version of the Flu Chip was tested outside of our lab, and it exceeded our expectations," she sa...

Seal rookeries could provide a reliable food source for endangered California condors, study finds

... and sea lion rookeries so that the birds can once again feast on the carcasses of marine mammals as their ...sses quickly disappeared. So the condors were once again stuck without a food source. Our isotopes show that the disappearance of the marine mammals coincide...

Scientists narrow the time limits for the human and chimpanzee split

... split of approximately 7 million years ago, which again was proportionally about one-fifth of the calibration time. "We can conclude that humans and chimpanzees probably last shared a common ancestor between five and seven million years ago," says Blair Hedges, professor of biology at Penn State. "Altho...

Sangamo BioSciences demonstrates its ZFP treatment protects cells from HIV infection

...y restored in the ZFN-modified cells, HIV was once again able to infect these cells. Sangamo has shown disruption of the CCR5 gene in a number of different cell types including T-cells, the target cell for this therapeutic approach. "CCR5 is an important target in the fight against HIV/AIDS," stated Edw...

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