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Tag: "affects" at biology news

A new mechanism of regulating RNA degradation

...MD). Preliminary results suggest that SMD activity affects numerous transcripts and, therefore, is a novel mechanism of gene regulation. "We don't yet understand how SMD is regulated but it must be," said Maquat. "Both Upf1 and Staufen1 can be phosphorylated, so their activities could be regulated by cell s...

FDA Approves Human Hookworm Vaccine for Phase I Safety Trials

...MD). Preliminary results suggest that SMD activity affects numerous transcripts and, therefore, is a novel mechanism of gene regulation. "We don't yet understand how SMD is regulated but it must be," said Maquat. "Both Upf1 and Staufen1 can be phosphorylated, so their activities could be regulated by cell s...

Fox Chase Cancer Center scientists identify immune-system mutation

...ed immune deficiency (SCID), a condition that also affects humans. In addition to providing a unique animal model to study the SCID syndrome, SCID mice have become a highly valuable tool for studying the immune system and are now used by scientists worldwide. Kappes' co-authors on the new Nature paper inclu...

Plants, animals share molecular growth mechanisms

...Szymanski's research team is delving into how this affects the growth process. "DIS3 has two ends that are common in both plant and animal proteins," he said. "But DIS3 has a very large segment in the middle that is specific to plants. We'd like to know if this section is important and whether it regulates ...

Researchers Uncover Key Step In Manufacture of Memory Protein

... Future research may determine if the CPE mutation affects these individuals?long-term memory. ...

Scientists detect probable genetic cause of some Parkinson's disease cases

...ders andStroke (NINDS). Parkinson's disease,which affects at least 500,000 Americans, is a progressive neurologicdisorder that is caused by the degeneration of nerve cells in theportion of the brain that controls movement. Scientists have longsuspected genetics plays a role in the onset of the disease. In t...

An HIV Protein Plays a Surprising Role in Gene Activation

... for HIV gene activation and viral replication. It affects these processes, the current model holds, by stimulating transcript elongation and increasing RNA polymerase's processing efficiency. In a new study, Tamal Raha, Grace Cheng, and Michael Green work with human cell lines and find evidence that Tat can...

Gene variations explain drug dose required to control seizures

...e time to determine because of the drug's variable affects on patient metabolism and its potential neurologic side effects. The team identified genes considered to be obvious candidates underlying patients' drug response, based on their known roles in the metabolism or transport of one or both anti-epilepti...

U-M scientists find genes that control growth of common skin cancer

...journal's Web site . Basal cell carcinoma (BCC) affects over 1,000,000 Americans each year and frequently develops onsun-exposed sites, such as the face. Surgical removal of BCCs is aneffective approach to treating these cancers, which generally have aslow growth rate and seldom spread or metastasize. How...

Studies reveal methods viruses use to sidestep immune system

...eplication. Hepatitis C is a chronic disease that affects 4 million people in the United States, making it the nation's most common blood-borne infection. It is transmitted primarily through intravenous drug use, blood transfusions or blood products, as well as through sexual contact and is the leading caus...

Research Using Mouse Models Reveals A Novel Key Player In The Initiation Of Colon Cancer

...leading to the conclusion that the Foxl1deficiency affects early stages in tumor formation. Additional analysis revealed that the Foxl1 deficiency affected the onset of tumor formation, accelerating them to arise in 1/3rd of the normal time. The authors examined the integrity of the APC gene in these tumor c...

Falling ants glide back to trunk to avoid dangers of forest floor

...anoviak is in Iquitos to explore how deforestation affects the mosquito transmission of Venezuelan equine encephalitis. In hopes of establishing a mosquito colony in the laboratory, he goes in search of mosquitoes and larvae in the canopy where they live, mostly above private land around the city. Using rope...

Chemists identify key gene in development of type 1 diabetes

...lin-dependent or juvenile diabetes, a disease that affects about one million people in the U.S. and is on the rise worldwide. They described their findings, which they say could lead to new drug interventions and possibly gene therapy, today at the 229th national meeting of the American Chemical Society, the...

Bone Density Recovers After Teens Stop Injected Contraceptive

...in. It is not known whether oral contraceptive use affects bone mineral density and NICHD is currently supporting a study to address this issue. The researchers measured the participants?bone mineral densities when the study began, and every six months thereafter for the next two to three years. During the ...

Towards precise classification of cancers based on robust gene functional expression profiles

...lin-dependent or juvenile diabetes, a disease that affects about one million people in the U.S. and is on the rise worldwide. They described their findings, which they say could lead to new drug interventions and possibly gene therapy, today at the 229th national meeting of the American Chemical Society, the...

Effective Cancer Treatments Follow The Clock

...ts found that the body's internal biological clock affects the survival of immune cells that are targets of the anti-cancer drug cyclophosphamide (CY). “We became interested in examining this issue because there is a long history of knowledge that chemotherapeutic agents produce different mortality and morb...

Genetically modified rice in China benefits farmers' health, study finds

...02 and 3.0 percent in 2003 reported adverse health affects related to pesticide use. ...

A new study examines how shared pathogens affect host populations

...ple to the idea that sharing pathogens necessarily affects host populations negatively. They show that if there is frequency-dependent transmission, a host can be rescued from pathogen-mediated extinction by the presence of a second host with which it shares a pathogen. Sharing a pathogen among one or more ...

Potential treatments for neurofibromatosis

...rrently little can be done to treat a disease that affects more people than cystic fibrosis, hereditary muscular dystrophy, Huntington's disease and Tay Sachs combined. Now, however, research by IU School of Medicine scientist D. Wade Clapp, M.D., and his colleagues David A. Ingram, Jr., M.D. and Feng-Chun ...

Cricket's finicky mating behavior boosts biodiversity

...s in terms of increasing biodiversity? If so, this affects how life on the planet looks. The more species you have, the more complex the ecology is going to be." In down-to-earth terms: "What turns a female cricket on? Why does she prefer one pulse rate over another? Whatever the reason, it's very importan...

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