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Tag: "affecting" at biology news

Gene therapy advance treats hemophilia in mouse models

...lia A is the leading sex-linked bleeding disorder, affecting one in 5,000 to 10,000 males. People with the condition have a genetic mutation that leaves them with little to no factor VIII protein to prevent uncontrolled bleeding. Individuals with the severe form of the disease have less than 1 percent of the n...

Pregnant women at higher risk for HIV, Uganda study finds

...ehaviors. It may be attributed to hormonal changes affecting the genital tract mucosa or immune responses," said Gray. ...

Snapin: A protein with therapy potential for autism

...y of dendric branching" ?a sequence of steps, each affecting the next, with cypin at the center. "Our pathway says cypin does this; now what regulates cypin? Here snapin has a role. And what does snapin regulate?" said Firestein. "Our hope is in ten years, we will have a whole pathway mapped out so that we can...

Compound might defeat African sleeping sickness, clinical trial beginning this month

... to help solve some very difficult health problems affecting millions of people in developing countries." ...

Assessing the Amazon River's sensitivity to deforestation

...ture deforestation to understand how humans may be affecting the Amazon. Coe says, "This research will provide us with a better understanding of how sensitive the Amazon river is to human activities and can provide government managers and civil society with a tool for analyzing the costs and benefits of differ...

Unraveling a stomach cancer puzzle

...ress stomach cancer formation, importantly without affecting Stat3's other important roles in the body. Add to that the evidence suggesting that Stat3 is also involved in breast, head and neck, and prostate cancers, and we have a compelling case for investigating the development of therapies that target Stat3....

Scientists find microRNAs regulate plant development

...h and development. Auxin influences development by affecting the expression of numerous genes that control the processes of cell division and cell expansion in specific plant tissues at specific stages during the plant life cycle - e.g. for leaves, roots, and floral organs to develop in the correct patterns an...

Newly discovered genetic disease sheds light on body's water balance

...is is the only reported example in which mutations affecting the same amino acid cause two different genetic di...enes and found that each boy had a unique mutation affecting the amino acid arginine at position 137 (R137). The single nucleotide change resulted in one baby ha...

Any exposure to tobacco smoke during pregnancy is risky

...have lifelong repercussions for the exposed fetus, affecting survival, birth weight and susceptibility to disease, including cancer." This is a startlingly different conclusion than that reached by three previous studies looking at the potential effects of tobacco smoke exposure to babies in the womb, one of ...

Survey reveals women and doctors aren't talking about HPV

...lth Professionals (ARHP). HPV is extremely common, affecting an estimated 80 percent of sexually active adults in their lifetime, in some cases staying dormant until years after the initial infection. Yet few are talking about the relationship between HPV and cervical cancer despite the fact that advanced scre...

Chronic Sinus Infection Thought To Be Tissue Issue, Mayo Clinic Scientists Show It's Snot

...most common chronic diseases in the United States, affecting 32 million adults, according to the National Center of Health Statistics. Chronic sinus infection produces nose and sinus problems characterized by stuffy nose, loss of sense of smell, postnasal drip, nasal discharge, and head and face pain lasting t...

Breakthrough System for Understanding Ocean Plant Life Announced

...te a drug that prevents the manufacture of base J, affecting the trypanosome's ability to vary its antigenic coating, and therefore allowing the human immune system to kill it. Understanding trypanosomes at the molecular level is key to fighting African sleeping sickness and diseases caused by similar parasit...

Newly discovered protein an important tool for sleeping sickness research

...te a drug that prevents the manufacture of base J, affecting the trypanosome's ability to vary its antigenic coating, and therefore allowing the human immune system to kill it. Understanding trypanosomes at the molecular level is key to fighting African sleeping sickness and diseases caused by similar parasit...

While on trail of dioxin, scientists pinpoint cancer target of green tea

Green tea appears to protect against cancer by affecting a "promiscuous" protein that pharmaceutical experts are already targeting in an effort to develop a new drug to stop the disease, scientists at the University of Rochester Medical Center have found. The research, which buttresses beliefs about the he...

UCLA study assesses cost-effectiveness of Hepatitis B drugs

...modern drugs for treating hepatitis B -- a disease affecting 350 million worldwide. Published in the May 17 An...stance, development of cirrhosis and other factors affecting treatment. Health costs included physician visits, diagnostic tests and complications of chronic liv...

NHGRI targets 12 more organisms for genome sequencing

...ct. Chagas' disease is prominent in Latin America, affecting about 20 million people in South America alone and killing 50,000 of them a year. Having the genome sequence of Rhodnius prolixus presents an opportunity for experts from the United States, Canada and Latin America to collaborate on understanding thi...

Radio-tracking associated with 'dramatic shift' in water vole sex ratio

...hers are being warned that radio-tracking could be affecting the animals they are studying. According to new research published today in the British Ecological Society's Journal of Applied Ecology, fitting radio-collars to water voles was associated with a "dramatic shift" in the sex ratio of the animals' offs...

Of mice and men's (and women's) contraceptives

...l lead to both male and female infertility without affecting the somatic cells." Animals deficient in the protein ?called MSY2 ?are infertile, but are otherwise healthy and completely normal. Male mice produce no functional sperm, and females show early loss of eggs and defects in ovulation. The MSY2 protein...

Cellular Defects in Premature Aging Disease are Reversible

...l aging process. HGPS is a rare inherited disease affecting about one in eight million children. While appearing normal at birth, infants with HGPS age rapidly after their first 18 months, and physical symptoms include stunted growth, loss of hair and body fat, joint stiffness, osteoporosis, and heart problem...

Compounds in plastic packaging act as environmental estrogens altering breast genes

...PA and BBP, are environmental estrogens capable of affecting gene expression in the mammary glands of young female laboratory rats exposed to the compounds through their mothers' milk. Raquel Moral, Ph.D., a postdoctoral associate in the Fox Chase laboratory of Jose Russo, M.D., presented the results today at...

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