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Tag: "affected" at biology news

Breakthrough in understanding type-2 diabetes as key genes identified

...ase processes involved, devise therapies for those affected and to try to prevent future cases," he added. ...

Genes and biomarkers that allow doctors to choose the right therapy for the right patient

...could select peptides that bind to tumors that are affected by a combination of radiation and tyrosine kinase inhibitor therapy, but not to tumors that do not respond to therapy. Ultimately, they uncovered 44 peptides that serve as biomarkers for response to therapy. According to Dr. Diaz, the physiological r...

Canada's new government invests $200M in the fight against the mountain pine beetle

...otecting communities and forest resources in areas affected by the infestation. Project activities will...umbia–Alberta border. The program will also assist affected communities in identifying new forest products, markets, industries and services to help ensure thei...

Prenatal cocaine's lasting cellular effects

... cautioned, is whether D1 receptor localization is affected in humans exposed to cocaine prenatally. If found in humans, "it gives us a new way to think about helping those children as they continue to mature." Because cocaine exposure seems to alter the distribution of the D1 receptor, Stanwood suggests ...

Researchers first to map gene that regulates adult stem cell growth

...he liver, skin, pancreas or brain may be similarly affected by Latexin. This could open up new therapeutic strategies such as using stem cells for the treatment of other diseases and conditions such as liver disease, diabetes and central nervous system damage as a result of trauma or stroke. The researchers...

Gene therapy for blindness clears hurdle in mice

...be sufficient to maintain vision in people who are affected by retinitis pigmentosa," Gorbatyuk said. "The second step, introducing the normal gene to the retina, will show whether we are able to restore vision in this model or not." If both steps are perfected, scientists plan to study the treatment in a ...

Ethanol vehicles pose a significant risk to human health, study finds

... ''The chemicals that come out of a tailpipe are affected by a variety of factors, including chemical reactions, temperatures, sunlight, clouds, wind and precipitation,'' he explained. ''In addition, overall health effects depend on exposure to these airborne chemicals, which varies from region to region. O...

Scientists discover a new risk factor for Alzheimer's

... More than 6,800 individuals--45.8 percent of them affected with the disease--were included in the analysis, which is considered a large data set in the field, said St George-Hyslop.. "We looked for variations of SORL1 in nine different groups of people and found those variations to be associated with an in...

Cancer researchers add spice to research against rare neuromuscular disease

...by breaking up a sort of molecular clog in neurons affected by Kennedy disease. The biology of the disease is bit like Huntington's disease, a more common neurodegenerative disease that is inherited, fatal, and unyielding in its progression. Both are caused by an abnormal repeat of three nucleotides, CAG, tho...

Freeze! Scientists film proteins at work by freezing them at different states

...d of water. This production is increased in people affected by neurodegenerative diseases such as Alzheimer. A high amount of these molecules worsen these illnesses, so scientists are looking for drugs to eliminate them. The enzyme studied by the team acts uniquely in bacteria and its counterpart in human...

Stretching DNA to the limit

...figure out the extent to which different bases are affected by UV light. They conclude that the changes in the force profile of viral DNA exposed to UV light are due to the local unwinding of the double helix in some regions arising from the massive formation of crosslinked structures. "These are the first...

Experience affects new neuron survival in adult brain; study sheds light on learning, memory

...s comparison indicates that only young neurons are affected by the repeated experience; once new neurons survive the early period of development, their long-term survival and activity become stable. This suggests that the information on the experience is kept for a long time, says Gage. "This finding indi...

Bacteria research offers hope for new vaccine against meningococci

...ven spark epidemics: in Africa 250,000 people were affected in a matter of weeks in the late 1990s. Without t...gies for improving the prognoses for those who are affected by meningococcus disorders,?says Ann-Beth Jonsson....

New hereditary breast cancer gene discovered

...eover, many of the women were young when they were affected by breast cancer," says Göran Stenman. The findings of the study show that women with this syndrome should be receive early mammograms in order to discover breast cancer at an early stage. "We have already started to use this new knowledge in...

Morphine makes lasting -- and surprising -- change in the brain

... and sex ?a reward system linked to addiction. The affected synapses, Kauer found, were those between inhibitory neurons and dopamine neurons. In a healthy brain, inhibitory cells would limit the release of dopamine, the "pleasure chemical" that gets released by naturally rewarding experiences. Drugs of abuse...

Army research mission focused on autism

...ult is that each combination to unlock each person affected is so unique." As a result of advocacy efforts,...g the disease can hear the issues of those persons affected by the disease, the scientific community and the advocacy community can partner to find and fund the...

Killing the messenger RNA -- But which one?

...roRNAs. It was. Then they chose one potentially affected gene at random to explore the ramifications of microRNA editing in depth. As it turned out, the gene they selected, known as PRPS1, codes for an essential enzyme involved in synthesizing uric acid. If levels of the enzyme are poorly regulated, a numb...

Blocking immune cell action increases Alzheimer's-associated protein deposits

...at attract immune cells and are elevated in brains affected by Alzheimer's, the receptor could be important for the movement of microglia to the site of amyloid-beta deposits. To test that possibility, the investigators used a mouse model of Alzheimer's disease and generated strains in which one or both copi...

Reactivated gene shrinks tumors

...researchers are not sure why these two cancers are affected in different ways, but they have started trying to figure it out by identifying the other genes that are activated in each type of tumor when p53 turns back on. The study also revealed that turning on p53 has no damaging effects in normal cells. T...

Turning a cellular sentinel into a cancer killer

...is colleagues found no evidence that restoring p53 affected normal cells. "That gives us a broader therapeutic window in which the cancer cells respond rapidly by one of these two mechanisms, whereas normal cells seem to tolerate reactivation of p53 quite well," he said. In the December 29, 2006, issue of t...

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