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Tag: "affected" at biology news

Soft-cell approach cuts animal tests

...hat are more likely to be significantly exposed or affected by air pollutants. As the respiratory system is both a site of toxicity for pulmonary toxicants, and a pathway for inhaled chemicals to reach other organs, relevant airway cells and lung cells are a major focus for inhalation studies. The advanta...

Hotspots of mercury contamination identified in eastern North America

...ces included in the study, and loons are adversely affected by mercury levels they experience. The hotspots ...ighly sensitive to the element or that are already affected by it could raise the risk to people and wildlife that consume fish. There is reason to believe, how...

Lithium builds gray matter in bipolar brains, UCLA study shows

... look at specific regions of the brain that may be affected by lithium treatment in living human subjects, sai...esearchers to see exactly which brain regions were affected by lithium. "Bipolar patients who were taking lithium had a striking increase in gray matter in ...

Stem cells act through multiple mechanisms to benefit mice with neurodegenerative disease

...-Sachs are relatively rare, one person in 5,000 is affected by a disease that falls into a category of lysosomal storage diseases. Currently there is no treatment for Sandhoff or Tay-Sachs. Given that the human stem cells used in this study-both human neural and embryonic stem cells-were safe and effec...

Massive coral death attributed to earthquake

... Simeulue is not all bad. At many sites, the worst affected species are beginning to re-colonize the shallow reef areas. The reefs appear to be returning to what they looked like before the earthquake, although the process may take many years. "The challenge now is to work with local communities and govern...

Common gene version optimizes thinking -- but with a possible downside

...asks, likely by increasing gene expression. In 257 affected families, people with schizophrenia were more likely to have this common version of the DARPP-32 gene. ...

A genetic 'gang of 4' drives spread of breast cancer

... next explored how loss of the four abnormal genes affected the metastatic capability of the cells in the lung. They injected cells deficient in the four genes directly into the circulatory system of mice. "When these cells reached the lung capillaries, they just got stuck there," said Massagué. "We concluded...

Robotic exoskeleton replaces muscle work

...worn by healthy subjects to measure how the device affected ankle function. The U-M team has no plans to build a commercial exoskeleton, but their results suggest promising applications for rehabilitation and physical therapy, and a similar approach could be used by other groups who do build such technology. ...

Researchers find gene mutation that causes infertility in male mice

...tudy it like you would other diseases, because the affected people can't reproduce," said John Schimenti, director of Cornell's Center for Vertebrate Genomics and senior author of the paper published in the current issue of the Public Library of Science journal PLoS Biology. Laura Bannister, a research associ...

Cold sore virus might play role in Alzheimer's disease

...have more herpes DNA in the brain regions that are affected by Alzheimer's, compared to Alzheimer's patients w... earliest change that could be detected in a brain affected by Alzheimer's disease, before any of the hallmark plaques or tangles and certainly long before any ...

Robotic therapy helps restore hand use after stroke

... may help people regain strength and normal use of affected hands long after a stroke, according to a Universi...d reduced function of the right hand, although the affected hands were neither totally paralyzed nor unable to feel. Seven women and six men who had suffered a ...

Angelman syndrome deficits rescued in mice

...aMKII, an enzyme highly expressed in brain regions affected by Angelman syndrome. The results, which appear in the March issue of Nature Neuroscience (currently available online), reveal an important part of the mechanism underlying the condition and point to potential therapeutic targets for treating thes...

Scientists clone mice from adult skin stem cells

...isorders where researchers are only able to obtain affected tissue from autopsies," says Fuchs. If on the other hand, scientists are able to generate embryonic stem cells from the skin of a patient, for example an Alzheimer's patient, these embryonic stem cells might be used in the laboratory to enable sc...

Blame the brain for high blood pressure

... develop hypertension, and with 600 million people affected world wide, it is of pandemic proportions. The alarming statistic that nearly 60 per cent of patients remain hypertensive, even though they are taking drugs to alleviate the condition, emphasises the urgency of looking for new mechanisms by which the...

MU researcher placing eye implants in cats to help humans see

...mising. "About one in 3,500 people worldwide is affected with a hereditary disease, retinitis pigmentosa, t...rimarily with Abyssinian and Persian cats that are affected with hereditary retinal blinding disease. The cat's eye is a good model to use for this type of rese...

Keeping the body in sync -- The stability of cellular clocks

... reflecting recent association studies in families affected by advanced sleep phase syndrome. Circadian rhythms are cyclical changes in physiology, gene expression, and behavior that run on a cycle of approximately one day, even in conditions of constant light or darkness. Peripheral organs in the body hav...

Researchers discover gene crucial for nerve cell insulation

...many genetic conditions, the unaffected copy of an affected gene continues to produce its protein. However, the researchers found that the mutant EGR2 copy interferes with the interaction between the normal EGR2 gene and another myelin gene, SOX10, as the two try to work together to produce the myelin protei...

New cell type identified in cancer development

...ults showed that the strength of the immune system affected whether or not the mice got cancer. The scientists found that the pCSCs, like normal stem cells, had the ability to create various types of benign cells in mice with healthy or recovering immune systems. These daughter cells, however, were likely to ...

Scientists sequence genome of parasite responsible for common sexually transmitted infection

...TIs," says Carlton. "Women are the population most affected by it, yet routine gynecological check-ups do not test for this particular infection, and it's not an STI that generally requires public health notification under state statutes. By better understanding the parasite's genetic structure, we hope to be...

Scientists find potential 'off-switch' for HIV virus

...s, however. For example, another enzyme within the affected cell called SirT1 is capable of pulling the chemical tail off the Tat protein, rendering it silent. The interplay between p300 and SirT1 comprises the resistor and can effectively keep the virus in its dormant phase. "SirT1 reduces the strength o...

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