Regulating the nuclear architecture of the cell
...esearchers' first step was to identify which genes affect organization of the heterochromatin, then to ident...rested in the larger question of how such pathways affect the organization of the chromosomes in the cell nucleus." ...Rising ocean temperatures, pollution have oysters in hot water
...higher temperature and cadmium exposure negatively affect the mitochondria's ability to produce energy. Blood oxygen falls In a second experiment, the researchers acclimated two groups of oysters to 20°C water. One group was exposed to cadmium. Both groups were then subjected to an acute temperature...Stem cells found in adult hair follicles may provide alternative to embryonic stem cells
...ll replacement therapy. Together, these conditions affect over 11 million people today in the US and are estimated to annually cost more than $170 billion. ...Novel mechanism of action of new drug for MS identified
...n immunosuppressant drug that was already known to affect the functioning of the immune system by preventing the egress of white blood cells from the lymph nodes into the blood. The article was pre-published as a First Edition Paper in Blood, The Journal of the American Society of Hematology, which appeared...Replacing insulin is top-ranked breakthrough foreseen for health in developing world
...ses, the primary targets of regenerative medicine, affect people at a younger age in developing than developed countries. They are also much more likely to be prevalent in the poor and have resulted in more deaths in 2005 than infectious disease, maternal and perinatal conditions, and nutritional deficienc...Leading reason for corneal transplants comes into focus
...phy causes swelling of the cornea and can severely affect vision, making it impossible to see well even with glasses or contact lenses. It's believed that various forms of FCD are due to multiple gene mutations. In a report in the September issue of Investigative Ophthalmology, a team led by Hopkins op...Poor athletic performance linked to vitamin deficiency
...s present in some athletes and individuals may all affect an individuals B-vitamin requirements, said Manore. "Many athletes, especially young athletes involved in highly competitive sports, do not realize the impact their diets have on their performance," said Manore, who is also an Extension Service nut...Extreme environment changes fish appearance
...ior, set out to see if environmental changes could affect how the fish looked. They reared a related but unthreatened species, the Amargosa pupfish, in the lab on a restricted diet and with slight changes in water temperature. The Amargosa pupfish began to look more like the wild Devils Hole pupfish. ...Brain regions do not communicate efficiently in adults with autism
...disorder in the United States. It is estimated to affect one in every 166 children. Autism is characterized by an inability to communicate and interact with other people, and those afflicted typically have a restricted range of activities and interests ...New HIV statistics indicate increasing toll of AIDS on African American community
...ith and dying from AIDS. The disease continues to affect African-Americans more than any other racial/ethnic group in the United States. Today, African Americans comprise only 13% of the U.S. population but account for over half of all new HIV/AIDS diagnoses. Over 200,000 African-Americans have died of A...Human stem cells delay start of Lou Gehrig's disease in rats
...g planned -- along the full length of the spine to affect upper body nerves and muscles as well might lead t...d rats with dead human stem cells, which would not affect disease progression. Both groups of rats were treated with drugs to prevent transplant rejection. ...For crickets, parasitic flies can stop the music
...004, hypothesized that the presence of flies would affect how male crickets sing and how females respond. Examining wild crickets native to North Florida, they devised two sets of experiments to test this hypothesis. In experiments involving male crickets, they gauged differences in male singing in part ...Adolescent but not adult hamsters are more aggressive on low dose of fluoxetine
... ways. We need to understand how these drugs will affect the developing nervous system before giving them to children." The neuroscientists explain that because adolescents may have lower levels of serotonin than adults, there may not be enough of it in their systems for the SSRI to work effectively. I...Exposure to dioxins influences male reproductive system, study of Vietnam veterans concludes
...not have very good evidence whether or not dioxins affect the human reproductive system," said Dr. Amit Gupta, a urologist at UT Southwestern and the study's lead author. "Now we know that there is a link between dioxins and the human prostate leading us to speculate that dioxins might be decreasing the gro...Single molecular 'mark' seen as pivotal for genome compaction in spores and sperm
... a template for the other. "Compaction might also affect sperm fertility and function in the higher organisms, and thus the propagation of the species," says Thanuja Krishnamoorthy, Ph.D., lead author on the study. "It's vital that we better understand genome compaction during the production of mature sper...Does natural selection drive the evolution of cancer?
... The final condition is that the variation has to affect fitness, the survival and reproduction of the cell...cteristics that are considered hallmarks of cancer affect fitness, according to Maley. Among these are that cancer cells no longer heed normal growth inhibiti...Two central mysteries in genome inheritance solved at UCSD
...er cells. "Right now, drugs used in chemotherapy affect microtubules in all the body's cells, resulting in adverse side effects, like nerve pain and loss of sensation ," said Desai. "If we could specifically target dividing cells, we should improve on current chemotherapy to treat the cancer with fewer s...Cellular traffic backups implicated in skeletal malformations
...fect. But, the crusher mutation appears to only affect chondrocytes, the cells that form the fish's cartilaginous skeleton. Chondrocytes secrete proteins like collagen into the extracellular space, laying down a rigid matrix (the extracellular matrix or ECM) that will form cartilage. Under a microscop...Two-faced protein can stop metastasis or promote it, researchers say
...cell bonding, in some cases it can also negatively affect cell adhesion. They also have found that over production of p120 increases a cell's ability to move. But the significance of these observations had eluded scientists. In this study, Masahiro Yanagisawa, M.D., Ph.D., a research fellow in Anastasiadis...