OneWorld Health drug receives 'Orphan' designation from U.S. and European regulatory agencies
...e EMEA regulations are similar, and have the added advantage of applying to all 25 members of the European Union. Orphan Drug Designation also provides incentives such as exemption from certain registration fees, and may help pave the way for approvals in other countries. OneWorld Health will file for approva...Oldest fossil human protein ever sequenced
...without the presence of vitamin C may have been an advantage to these primates if this nutrient was missing from their diets regularly. This research opens up the exciting possibility of extracting and sequencing protein from other fossils, including earlier humans, as a means of determining the relationships...Stanford gut check shows diversity of intestinal ecosystem
...the hundreds of types in the samples, Eckburg took advantage of a technique that compares the genetic sequence of a molecule shared by bacteria and archaea. The molecule, 16S rRNA, plays a role in the translation of the genetic code and thus is critical to the organisms. However, small variations in the 16S rR...Nature provides inspiration for important new adhesive
...some residential building products. The other key advantage of the new adhesives is their superior strength and water resistance. "The plywood we make with this adhesive can be boiled for several hours and the adhesive holds as strong as ever," Li said. "Regular plywood bonded with urea-formaldehyde resins c...Wake Forest scientists find new combination vaccine effective against plague
...s of vaccines. The new plague vaccine also has the advantage of not requiring a needle since only a few drops in the nose provide protection." In view of the exciting results with the plague vaccine, Mizel plans to determine if immunized monkeys are protected against the plague. If they are then efforts will ...Next Generation Body Scanner Launched By The University Of Manchester
...time means that more patients will be able to take advantage of the equipment, such as severely ill people who have previously been unable to tolerate the longer scanning times involved. John Atwill, Managing Director of Philips Medical Systems UK said: "The 3.0T Achieva MR system in Manchester represents the...Researchers pioneer new gene therapy technique using natural repair process
...l also have two each. The wounded chromosome takes advantage of the healthy copies created in preparation for d...n the new gene therapy technique, researchers took advantage of homologous recombination by introducing a man-made enzyme that recognizes and binds DNA at specif...Tsunami-damaged coral reefs should be left to recover naturally, say scientists
...Communities that are rebuilding hotels should take advantage of reconstruction funds to make sure there is effective sewage treatment available. And if builders are moving lots of earth around, they should do this in the dry season rather than the wet season to avoid sediment being washed into the sea." USEFU...Novel live reporting system to track cells
...aboration with the late Dr. Yoav Citri. Ferritin's advantage is that it is visible in MRI without the need for an additional contrast material. This technique has far-reaching implications for monitoring the progress of gene therapy, such as that used to reactivate the body's production of insulin in the treat...Diabetic nerve therapy shows 'striking' results
...eutically beneficial protein. The most significant advantage of this is that the protein is made as if the patient's body had made it naturally. "Our study has shown that a single treatment with a DNA-binding protein protected against nerve damage that in humans can lead to limb loss." The results of the pre...Bioinformatics reveals new gene regulation system
...positional clustering. Positional clustering takes advantage of the fact that functionally related gene sequences (such as the genes for Nrd and its transcription factor) frequently inhabit the same 'neighborhood' of the chromosome. "If you are looking in one genome, many genes will be neighbors by coincidenc...Speak up: Louder neurons form more connections
..., published in the April 21 issue of Nature, takes advantage of tiny, see-through zebrafish. Stephen Smith, PhD, professor of molecular and cellular physiology at the Stanford University School of Medicine, and his graduate student Jackie Hua immersed 3-day-old fish in a breathable, Jell-O-like substance that ...New method shows it is possible to grow bone for grafts within a patient's body
...en to be surprisingly simple. They decided to take advantage of the body's natural wound-healing response and create a special zone on the surface of a healthy bone in hopes that the body would respond by filling the space with new bone. The approach lived up to their highest expectations. Working with mature ...Confirmation of human protein interaction data by human expression data
..., published in the April 21 issue of Nature, takes advantage of tiny, see-through zebrafish. Stephen Smith, PhD, professor of molecular and cellular physiology at the Stanford University School of Medicine, and his graduate student Jackie Hua immersed 3-day-old fish in a breathable, Jell-O-like substance that ...Using nanoparticles, in vivo gene therapy activates brain stem cells
...apies for different tissues and cell types. A key advantage of the UB team's nanoparticle is its surface functionality, which allows it to be targeted to specific cells, explained Dhruba J. Bharali, Ph.D., a co-author on the paper and post-doctoral associate in the UB Department of Chemistry and UB's Institut...Achilles heel of the herpes virus possibly found
... viruses so far, HSV seems to have evolved to take advantage of a broadly present cellular protein that has properties like that of known cellular fusion machinery," says Fuller. "No other virus has been shown to use a cellular fusion protein for entry into cells." She explains that the search for the mechani...Newly discovered genetic disease sheds light on body's water balance
...etic hormone). However, when the UCSF doctors took advantage of new, rapid tests to measure vasopressin in these two infants, they found no detectable levels of the hormone in either child's bloodstream. They concluded that some other mechanism was disrupting fluid homeostasis. "This is a good example of the ...Insects develop resistance to engineered crops
...ive insect control, pyramided plants have an added advantage of requiring a smaller refuge -- a part of the field where non-Bt plants are grown. Refuges create opportunities for Bt-resistant insects to mate with other insects that do not have resistance. The offspring of such a mating will be susceptible to th...Multi-species genome comparison sheds new light on evolutionary processes, cancer mutations
...hese new analyses. Furthermore, the team took full advantage of the wealth of human, mouse and rat genome sequence data generated by the recently completed Human Genome Project." Chromosomes are the threadlike "packages" of DNA located in the nucleus of each cell. When cells divide, a chromosome occasionally ......ors that control movement. Their work, which takes advantage of a new technique for visualizing tissues in their natural state, provides new insights into the molecular basis of muscle relaxation, and perhaps its activation too. "We have solved the structure of the array of miniature motors that form our mus...