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Tag: "advanced" at biology news

Scientist works to improve treatment for brain tumors

..., we hope to optimize the clinical delivery of the advanced form of the drug," said Debinski. Debinski directs the Wake Forest Brain Tumor Center of Excellence. The goal of the center, which was formed in 2003, is to find better treatments ?and one day a cure ?for malignant brain tumors. In addition to its f...

Scientists use gene signatures to match cancer and other diseases with potentially effective drugs

...gest new therapies for drug-resistant leukemia and advanced prostate cancer. Scott Armstrong, MD, PhD, a ped...astrol and gedunin, with a mechanism by which some advanced prostate tumors continue to grow aggressively despite hormone-blocking treatments. A paper in Cancer...

Major cancer study aims to identify protein markers for early-stage disease

...e complex data produced by mass spectrometry using advanced computing techniques ?a science known as bioinformatics -- will be critical for making sense of the information, says Fisher. Part of the challenge will be the need to piece together data on fragments of individual proteins, rather than whole molecul...

ABCB6 is key to production of heme in hemoglobin

...for life. A report on these results appears in the advanced online publication of Nature. Inside the mitochondrion, porphyrins are converted to heme. Heme is the oxygen-carrying part of the red blood cell molecule called hemoglobin, as well as a critical part of certain liver enzymes that break down toxins, ...

Analysis of breast-cancer gene role offers promising target

...or or circulating tumor cells ?of 72 patients with advanced recurrent breast carcinoma, the UT Southwestern research team discovered how uPAR may work in concert with another known breast cancer gene, HER-2. The researchers suggest that uPAR may amplify the cancer-causing effects of HER-2. "This gene, ...

Combination therapy shows promising results in patients with advanced lung cancer

...matory produced promising results in patients with advanced lung cancer, researchers at UCLA's Jonsson Cancer ...." Volunteers in the Phase I study, patients with advanced lung cancer that had failed to respond to all conventional therapies, took several Celebrex pills an...

High-tech research shows cocaine changes proteins and brain function

...y of Medicine. The researcher used technology so advanced it was like looking for differences in brain tissue with "floodlights" rather than a "flashlight," he said. Hemby and his colleagues analyzed thousands of proteins from brain tissue obtained from individuals who died of cocaine overdose and compared ...

Patients to benefit from novel technology revolutionizing high-speed molecular imaging

The new technologically advanced D-SPECT camera enables shorter image acquisition times, provides better image quality and opens the door to new diagnostic procedures using simultaneous multi-isotope imaging--providing the potential to revolutionize functional imaging, according to ...

Copying nature could save us energy, study shows

...y of Bath is helping extend this principle to more advanced engineering challenges. Researchers are currently looking at the desert cockroach (to develop a new kind of dehumidifier technology), insect sense organs (for structural health monitoring) and the egg-laying organ of a wood-wasp (for a new type of s...

Large-scale genomics project will hunt genes behind common childhood diseases

...sible for common childhood diseases. Making use of advanced automated technology from the biotechnology company Illumina, Inc., the Hospital's new Center for Applied Genomics will house one of the world's largest programs for genotyping--the process of detecting gene variations, with the aim of linking them t...

NYU algorithm enhances ability to detect cancer genes

...age" to the genomes as the cancer progresses to an advanced stage. The NYU algorithm estimates the location of tumor suppressor genes by analyzing segmental deletions in the genomes from cancer patients and the spatial relation of the deleted segments to any specific genomic interval. Since the gene-chip con...

Scientists tie several cancers to common 'oncogene engine'

... rare but dramatic responses in some patients with advanced melanoma. "We have just opened a trial to offer the same vaccine to patients with all of the other cancers in this related family," said Fisher. "Prior to this, virtually no rational experimental treatments were available for these diseases, and pati...

Researcher studies, treats military with 'silent disease'

...iopsy, if one hadn't already been done, to see how advanced the disease was. At the end of four years, a secon...disease, Sjogren said. Of the 70 percent with more advanced liver disease, 15 to 20 percent had cirrhosis, a condition in which scar tissue replaces healthy tis...

Prevention is the best option: fighting autoimmune diseases

...enary Institute. The machines use laser beams and advanced optics and electronics toanalyse and purify many kinds of cells at a rate of over 25,000 cells every second. This technology is able to produce results that cannot be obtained by any other method as it allows every cell to be identified and sorted on...

Hopkins scientists show hallucinogen in mushrooms creates universal 'mystical' experience

...ges in outlook. The study, Griffiths adds, has advanced understanding of hallucinogen abuse. As for wh...eam is planning a trial of patients suffering from advanced cancer-related depression or anxiety, following up suggestive research several decades ago. They're ...

Acidity in the brain could hold the key to stroke treatment

... detect. Professors Morris and Kauppinen will use advanced Nuclear Magnetic Resonance (NMR) technologies to allow MRI scanners to create detailed images of pH in the brain. The images will be used to compare healthy (neutral, pH 7) and damaged (acidic, lower pH) areas of the brain, and to measure how the pH...

Allergy battle could be won in five years, says scientist

...nces, said work on the first ADI chemical was well advanced and potential drugs could enter clinical trials as early as 2010. If successful, the drug would treat established symptoms already found in adult sufferers and, in due course, could be used to prevent allergies in children. "Prevention of allergi...

Defense peptide found in primates may block some human HIV transmissions

As primates evolved 7 million years ago, the more advanced species stopped making a protein that University o...etrocyclins, which are no longer made by humans or advanced primates such as chimpanzees. However, theta-defensins are more active against HIV-1 than the other ...

Researchers show how brain decodes complex smells

.... Instead, the bulb likely passes the data to more advanced brain structures where it is assembled and recognized as a specific scent. Understanding how the olfactory system works in mice may also provide broader insights into human perception, said Stephen Shea, Ph.D., a Duke University Medical Center resea...

Fatty spheres loaded with siRNA shrink ovarian cancer tumors in preclinical trial

... ovarian cancer cell lines derived from women with advanced cancer were treated for 3-5 weeks. They received liposomes that contained either the FAK siRNA, a control siRNA, or were empty. Some mice received siRNA liposomes plus the chemotherapy docetaxel. Mice receiving the FAK-silencing liposome had redu...

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