NHGRI aims to make DNA sequencing faster, more cost effective
...d probes, the methods of force spectroscopy can be advanced into techniques having massively parallel format, where millions of single DNA base additions can be followed at the same time. The identification of bases will be done exclusively on the basis of changes experienced by the molecule as a whole. The t...Older fathers more likely to have autistic children
... study provides the first convincing evidence that advanced paternal age is a risk factor for autism spectrum disorder," they conclude. ...Muscle and bone from an ink-jet printer
...ork by combining the versatile ink-jet system with advanced live cell imaging developed at Carnegie Mellon’s Robotics Institute and Molecular Biosensor and Imaging Center to further understand how stem cells differentiate into bone, muscle, or other cell types. ...Pourquié lab identifies genes involved in formation of vertebral precursors
... The paper was published on Science Express, the advanced publication Web site of Science Magazine on Nov. 9, 2006. Dr. Pourquié's lab has long studied the formation of the spine and the role of an internal mechanism -- the clock oscillator -- that regulates the formation somites, the precursors of ver...Replacing insulin is top-ranked breakthrough foreseen for health in developing world
...ules, genetic engineering, tissue engineering, and advanced cell therapy. There is increasing research in regenerative medicine in both developed and developing countries. Already regenerative medicine has produced a skin substitute (Apligraf), a bone regenerating therapy (Osteocel) and other medical breakth...Molecular structure reveals how botulinum toxin attaches to nerve cells
...akes to gain entry into human neurons. In an advanced online publication of the journal Nature, the scientists show structurally how botulinum neurotoxin B (one of seven toxins the bacterium produces) recognizes receptors on the surface of human neurons. The structure reveals how these toxins work at th...Abnormal overexpression of p53 is a predictive molecular biomarker
..., Inc., in Austin, Texas, found that patients with advanced squamous cell carcinoma of the head and neck cance...e when combined with chemotherapy to treat locally advanced breast cancer, and a 69 percent response when used with radiation to treat non-small cell lung cance...Protein folding: Building a strong foundation
...d a solid, sturdy chassis. A new study combining advanced computational modeling and cutting-edge experiments by molecular biologists at Rice University and Baylor College of Medicine suggests that the most stable parts of a protein are also the parts that fold first. The findings appear in the Sept. 13 i...Innovative movies show real-time immune-cell activity within tumors
Using advanced new microscopy techniques in concert with sophisticated transgenic technologies, scientists at The Wistar Institute have for the first time created three-dimensional, time-lapse movies showing immune cells targeting cancer cells in live tumor tissues...Affymetrix 500K array used to identify memory gene
...emory study is a perfect example of how the use of advanced technologies in human genetics yields fundamental discoveries," said Stephen P.A. Fodor, Ph.D., chairman and CEO at Affymetrix. To learn more about this breakthrough: ...Researchers map spread of pathogens in the human body
...s. For this study, the Cambridge researchers used advanced fluorescence microscopy techniques to observe intracellular growth of Salmonella bacteria within living cells....'Killer' B cells demonstrate evolutionary link between fish and mammal immune systems
...immune systems of amphibians and fish are far less advanced than ours," Sunyer said. "When you only have a ru...ral differences, the fish B cells represent a less advanced version of mammalian B cells. Sunyer found the very cellular structures that medical science has us...New data from NIH lab confirms protocol to reverse type 1 diabetes in mice
... recovery more in mice who are older and with more advanced diabetes compared with younger mice with less advanced diabetes, in which regeneration of remaining islets may be the dominant mechanism. ...New biochip helps study living cells, may speed drug development
...easure multiple ions at once and perform even more advanced functions such as electrically stimulating a cell with one electrode while recording the reaction with the remaining three. Because ion channels are a prominent feature of the nervous system and elsewhere, they are a popular target for drugs. For ...Complexity constrains evolution of human brain genes
...a correlate of smaller population size in the more advanced species. Species with smaller population size can.... "The slowdown in genetic evolution in the more advanced organs makes sense," he said, "only when one takes a systems perspective."...Mayo Clinic collaboration mining of ancient herbal text leads to potential new anti-bacterial drug
...s nontraditional, ancient medical information with advanced technologies to identify promising natural products to investigate as drugs for new and better therapies. "Natural products are invaluable sources of healing agents -- consider, for example, that aspirin derived originally from willow bark, and th...A new jump start for aging blood vessels
...ngs in their study. First, they confirmed that in advanced aging, increased TNFa levels were associated with significant impairment of vessel relaxation, which is required for proper regulation of blood pressure. Second, blocking TNFa via chronic etanercept treatment decreased cell death in aged vessels...Sandia research to focus on early detection of harmful algal blooms
...of water infrastructure through the development of advanced technologies that create new water supplies, decrease demand through water-use efficiency, and provide decision-informing tools to the institutions responsible for balancing supply and demand. ...Inflammation markers identify fatigue in breast cancer survivors
...enge to women diagnosed with the disease, but with advanced screening and treatment strategies, patients with early stage breast cancer are surviving longer. Breast cancer survivors are the largest group of patients to overcome any type of cancer in the United States. While patients surviving other types of c...Solved: The mystery of flesh-eating bacteria's relentless attack
...s IL-8. Drawing on a database of enzymes and using advanced techniques that measure the levels of gene transcription products in a cell, they soon identified the culprit: an enzyme called ScpC. The team then created a mutant variation of the M14 strain of Streptococcus that could not produce ScpC. As expec...