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Tag: "advanced" at biology news

Mailman School of Public Health researchers report blood DNA can be early predictor of liver cancer

...ular or liver carcinomas (HCC) are diagnosed at an advanced and usually fatal stage, the development of screening methods for early detection is critical. HCC is one of the most common and rapidly fatal human malignancies. Worldwide, the almost 500,000 new cases and nearly equivalent number of fatalities ill...

Novel antigen-cloning technique may boost efforts to develop a melanoma vaccine

...en to develop a melanoma vaccine for patients with advanced disease. "And because the RPL8 antigen is expressed by breast cancer and gliomas, we may be able to develop a vaccine that could be used to treat these types of cancer, as well." ...

Keeping the body in sync -- The stability of cellular clocks

...recent association studies in families affected by advanced sleep phase syndrome. Circadian rhythms are cyclical changes in physiology, gene expression, and behavior that run on a cycle of approximately one day, even in conditions of constant light or darkness. Peripheral organs in the body have their own ...

Protein overexpression at heart of heart failure

...ity, and dysregulation of [Ca2+]i is a hallmark of advanced heart failure.2 The primary trigger for cardiac [Ca2+]i transients is calcium entry through the pore subunit of the voltage-dependent L-type channels (L-VDCC), but their role in heart failure is still controversial. Electrophysiological studies on in...

Scripps research study reveals structural dynamics of single prion molecules

...le manner. The research team used a combination of advanced biophysical methods to investigate these processes. "By focusing on single unfolded prions, we were able to define the dynamics of two distinct regions or domains that determine conversion dynamics," said Ashok A. Deniz, a Scripps Research scienti...

Using brain scans, researchers find evidence for a two-stage model of human perceptual learning

Using advanced brain imaging techniques, researchers at Georgetow...e their brain activity was being measured using an advanced functional Magnetic Resonance Imaging (fMRI) technique that made it possible to more directly probe ...

Scientists discover new life forms in the Arctic Ocean

... to be brought into culture, but can be seen using advanced microscopy techniques. "It's a very exciting discovery," comments Dr. Lovejoy. "The ocean covers 70% of planet earth and we are only now coming to appreciate its rich and complex biodiversity." The other members of the team responsible for this ...

Gene that makes people 'early to bed and early to rise' demystified

... and early to rise," a condition known as familial advanced sleep phase syndrome (FASPS), offered one of the first glimpses into the genetic basis of sleep in humans. Now, researchers report in the Jan. 12, 2007 issue of the journal Cell, published by Cell Press, new evidence that helps to explain just how th...

Genes and biomarkers that allow doctors to choose the right therapy for the right patient

...ual’s response to Tykerb. "Our goal is to apply advanced cellular genomic strategies to assist clinical drug development by finding gene states that predict a patient’s response to a specific drug, and which combination of drugs produce the most favorable response." said Spyro Mousses, Ph.D., director of t...

Inflammation may play role in metastasis of prostate cancer

...tion and Maspin production was detected, such that advanced prostate cancer cells contain high amounts of acti...ligand, produced by inflammatory cells that invade advanced prostate tumors, triggers a chain reaction in which IKKa is activated, allowing it to enter the nucl...

QUT scientists on the way to sifting out a cure for HIV

...ceramic membranes for nanofiltration, which are so advanced they have the potential to remove viruses from water, air and blood. Associate Professor Huaiyong Zhu, from QUT's School of Physical and Chemical Sciences, is leading the development of these membranes, also known as nano-mesh, and said preliminar...

Scientists map key landmarks in human genome

...Biotechnology, which has published the paper as an advanced online publication on its Web site, www.nature.com/nbt/journal/vaop/ncurrent/index.html . "This study presents the first global view of human nucleosome positioning," said Fisher. Although analyses of this type had been pioneered in simpler organ...

Sunshine pill for prostate cancer in 2009

...of the sun could be available for the treatment of advanced prostate cancer as early as 2009. But it remains t...based on vitamin D and is given to patients in the advanced stages of prostate cancer along with chemotherapy drugs. Drug makers came up with the idea because ...

Chemical switch triggers critical cell activities

...l. A report on this work appears in the January 14 advanced online publication issue of Nature. The St. Jude discovery explains how a simple chemical link between molecules called a thioester bond acts like a switch to control the handoff of a protein called NEDD8 like a baton from one enzyme called E1 to a...

Molecular signature may identify cisplatin-sensitive breast tumors

...ming weeks, the trial will be open to patient with advanced triple-negative breast cancer and eventually will be offered at other U.S. cancer research centers. Patients or physicians interested in the trial should call Karleen Habin at (617) 726-1922 and ask about the cisplatin trial for breast cancer....

Intravenous nanoparticle gene therapy shows activity in stage IV lung cancer

...lation was developed and tested in Roth's lab. It advanced to phase I clinical trial after a promising test on human non-small cell lung cancer in a mouse model. FUS1 was discovered by a research team led by Roth at M. D. Anderson and by John Minna, M.D., of the Department of Internal Medicine and Phar...

Napoleon's mysterious death unmasked, UT Southwestern researcher says

...al accounts and found that Napoleon died of a very advanced case of gastric cancer that stemmed from an ulcer-...nd chemotherapies, patients with gastric cancer as advanced as Napoleon's have a poor prognosis." Napoleon, born Aug. 15, 1769, ruled France in the late 1700...

Knocking out survival protein could aid leukemia treatment

...he same even in cells that came from patients with advanced cancer or from patients with tumors that resisted conventional treatment. When the researchers treated cells with both siRNA and the drug rituximab, the combination killed significantly more leukemia cells than the drug alone. Overall, says B...

Stanford scientists make major breakthrough in regenerative medicine

...tion in human regenerative medicine—a future where advanced organ damage can be repaired by the body itself. In the May 2007 issue of The FASEB Journal, researchers show that a human evolutionary ancestor, the sea squirt, can correct abnormalities over a series of generations, suggesting that a similar regene...

Pacific Rim researchers to collaborate on distributed bioinformatics analysis of avian flu

...mmand (USAMRMC). TATRC invests in telemedicine and advanced medical technologies in order to deliver world-class health care to military personnel. The increasing frequency of biological events relevant to national security, and current disease surveillance systems in the United States (U.S.) require an integ...

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