Boosting The BCG Vaccine To Beat Tuberculosis
...ates. In a study appearing online on August 18 in advance of print publication of the September 1 issue of the Journal of Clinical Investigation, Stefan Kaufmann and colleagues from the Max Planck Institute devise a strategy to boost the immunogenicity of BCG and describe a novel vaccine strain with high ef...Researchers Discover Ancient Origins Of Tuberculosis-causing Bacteria
...ates. In a study appearing online on August 18 in advance of print publication of the September 1 issue of the Journal of Clinical Investigation, Stefan Kaufmann and colleagues from the Max Planck Institute devise a strategy to boost the immunogenicity of BCG and describe a novel vaccine strain with high ef......ates. In a study appearing online on August 18 in advance of print publication of the September 1 issue of the Journal of Clinical Investigation, Stefan Kaufmann and colleagues from the Max Planck Institute devise a strategy to boost the immunogenicity of BCG and describe a novel vaccine strain with high ef...Monkeying around to improve organ transplantation
...itro. Now in a study appearing online on June 9 in advance of the print publication of the July 1 print issue of the Journal of Clinical Investigation, Hisashi Bashuda and colleagues from Juntendo University investigate whether this approach can induce indefinite organ allograft survival in vivo, in six rhes...Hopkins scientists uncover 'tags' that force proteins to cell surface
...reactions, the findings, described in the Sept. 11 advance online publications of Nature Cell Biology, might revolutionize efforts in drug and vaccine development, says the Hopkins team. "A typical step in drug development is to get cells in a dish to express the protein you want to target with drugs, and t...Researchers make 'embryonic-like' stem cells from umbilical cord blood
...previous critics of stem cell research. The latest advance looks set to overcome such difficulties. The trans-Atlantic team has been working with Drs Randall Urban, Larry Denner and Ronald Tilton from the University of Texas Medical Branch in Galveston. They have been using bioreactors at the Synthecon Corp...Insight into the processes of 'positive' and 'negative' learners
...previous critics of stem cell research. The latest advance looks set to overcome such difficulties. The trans-Atlantic team has been working with Drs Randall Urban, Larry Denner and Ronald Tilton from the University of Texas Medical Branch in Galveston. They have been using bioreactors at the Synthecon Corp...Researchers propose measures to curb lion attacks in Tanzania
...previous critics of stem cell research. The latest advance looks set to overcome such difficulties. The trans-Atlantic team has been working with Drs Randall Urban, Larry Denner and Ronald Tilton from the University of Texas Medical Branch in Galveston. They have been using bioreactors at the Synthecon Corp...Clear rules needed to govern deep sea bioprospecting: UNU
... recognition of the potential of deep sea genes to advance human welfare. The new report, Bioprospecting of Genetic Resources in the Deep Seabed (online at http://www.ias.unu.edu/binaries2/DeepSeabed_FINAL.pdf), cites rising concern about the absence of clear rules governing access to and the sharing of ben...A Father’s Day Gift: Free DNA Paternity Testing
... recognition of the potential of deep sea genes to advance human welfare. The new report, Bioprospecting of Genetic Resources in the Deep Seabed (online at http://www.ias.unu.edu/binaries2/DeepSeabed_FINAL.pdf), cites rising concern about the absence of clear rules governing access to and the sharing of ben...New technique may speed DNA analysis
...make DNA analysis routine, "we could know years in advance of cancer, hepatitis, or Alzheimer's." Another benefit would be large-scale diagnostics that could provide useful information about disease. Take diabetes. "We don't know if it's genetic. The only way to find out is to test a lot of people," said St...New technique helps identify multiple DNA regulatory sites
...make DNA analysis routine, "we could know years in advance of cancer, hepatitis, or Alzheimer's." Another benefit would be large-scale diagnostics that could provide useful information about disease. Take diabetes. "We don't know if it's genetic. The only way to find out is to test a lot of people," said St...NHGRI Selects 13 More Organisms for Genome Sequencing
...oposal for a set of genomes to sequence that would advance knowledge in one of two important scientific areas: understanding the human genome and understanding the evolutionary biology of genomes. A coordinating committee then reviews the working groups?proposals, helping to fine-tune the suggestions and int...Possible treatment found for 'chemobrain'
...oposal for a set of genomes to sequence that would advance knowledge in one of two important scientific areas: understanding the human genome and understanding the evolutionary biology of genomes. A coordinating committee then reviews the working groups?proposals, helping to fine-tune the suggestions and int...Biota makes major antiviral discovery
...s on the heels of the company's recent decision to advance its common cold (human rhinovirus, HRV) drug candidate into clinical development following a similarly successful in-house research program. ...Targeting a key enzyme with gene therapy reversed course of Alzheimer's disease in mouse models
...ity of California in San Diego, are reported in an advance on-line publication of Nature Neuroscience. In the past, gene therapy has been mainly used to deliver normal genes into cells to compensate for defective versions of the gene causing disease. In their study, the researchers used gene therapy to sile...Newly Discovered Role for Heart Response Enzyme May Yield Better Heart Failure Therapy
...ure Cell Biology. The study is now available as an advance online publication. "We've uncovered new details of the first step of heart failure, in which heart receptors that normally allow the heart to adapt in the face of changing conditions are lost, rendering the heart unable to pump enough blood to meet...Columbia scientists develop cancer terminator viruses
Results advance quest for viral-based therapies for cancer Researchers at Columbia University Medical Center continue to make strides in their work to develop the next generation of effective viral-based therapies for cancer. Two papers about promising research wi...UCSD discovery may provide novel method to generate medically useful proteins
... tool to develop novel drugs. In the September 18 advance on-line publication of the journal Nature Structural and Molecular Biology, the researchers describe the mechanism by which a virus that infects bacteria--called a bacteriophage, or phage--can generate a kaleidoscope of variants of a particular prote...Sensor web simulation investigates technique to improve prediction of pollution across the globe
... Such models can be used to provide alerts days in advance so that people sensitive to pollutants can modify planned outdoor activities to minimize their exposure. The troposphere is where we all live, work, play and breathe! It's the region of the atmosphere where our weather occurs and it extends from the...