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Tag: "advance" at biology news

Researchers discover molecular mechanism that desensitizes us to cold

...els the cold. The study, published this week as an advance online publication by Nature Neuroscience, focused on a specific region of the cold receptor which is found in many other receptors, including ones involved in taste, vision and fertilization. Therefore, the findings may have important implications a...

Not-for-profit publishers call NIH public access rule a missed opportunity

...p with NIH on publications and other activities to advance science and health," said M. Michele Hogan, PhD, Executive Director, American Association of Immunologists. "Our journals provide high quality peer-review, editing, and publication services for NIH-funded research." "These societies and the journals...

PGA on a tour under the skin

... In their study appearing online on February 3 in advance of publication in the March 1 print edition of the Journal of Clinical Investigation,.Michael Otto and colleagues from Rocky Mountain Laboratories demonstrate that S. epidermidis secretes an extracellular polymer called poly-gamma-glutamate (PGA) to ...

New insight into regulation of blood stem cells

Scientists have made a significant advance toward understanding the regulation of blood stem cells and the complex, lifelong process of blood cell formation. A research study published in the February issue of Developmental Cell expands on previous studies by using adult animals to examine th...

Birds brains reveal source of songs

...ut his recent study, which was published online in advance of the May issue of the free access journal, Public Library of Science Biology. "We've known there are several brain areas involved: a motor circuit for producing the song, and a learning circuit, called the AFP (for anterior forebrain pathway), that...

FDA Announces Series of Changes to the Class of Marketed Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)

...ge/cox2/default.htm. "Today's actions protect and advance the health of the millions of Americans who rely on these drugs everyday," said Dr. Steven K. Galson, Acting Director of FDA's Center for Drug Evaluation and Research (CDER). "FDA is providing the public information based on the latest available scie...

Leprosy microbes lead scientists to immune discovery

...of Public Health, reported the work on May 8 in an advance online publication of Nature Medicine. The researchers isolated immune cells in blood samples from healthy people and exposed the cells to a component of mycobacteria. The large white blood cells known as monocytes rapidly differentiated into the tw...

Study: 'homemade' gene expression technology unreliable

... revolution in technology that is hoped rapidly to advance understanding of biological mechanisms and methods to assess the actions and effects of drugs and chemicals," said Spencer, who estimates there are "hundreds, if not thousands" of laboratories around the country using DNA microarrays. Microarray pla...

Biomarkers isolated from saliva successfully predict oral and breast cancer

... however, has been stalled until recently with the advance of several emerging technologies including improved methods to identify, collect, preserve and amplify genetic material and proteins. In this study, the UCLA team found they could isolate messenger RNA from saliva and blood sera that might have diag...

Defensins Ward Off HIV In Two Ways

...not been known. Appearing online on February 17 in advance of publication in the March 1 print edition of the Journal of Clinical Investigation, Theresa Chang and colleagues from Mount Sinai School of Medicine analyze how alpha-defensin-1, in particular, inhibits HIV infection in CD4+ T cells. CD4 + T cells ...

Bevacizumab Combined With Chemotherapy Improves Progression-Free Survival for Patients With Advanced Breast Cancer

...patients with breast cancer and represents a major advance in the treatment of patients with metastatic disease," said Study Chair Kathy D. Miller, M.D., of the Indiana University Medical Center in Indianapolis, Ind. Anti-angiogenic drugs, also called angiogenesis inhibitors, are substances that may prevent ...

Changing ecosystems throw scientists mega-challenges

...velopment, answering questions in that domain will advance scientific understanding while addressing urgent societal issues. The report states those results could then be applied to other potential focus areas for research on complex environmental systems, such as land use, energy and climate. ...

Gene keeps neural cells on correct developmental path

...postdoctoral fellow in Mandel's lab, the study may advance stem cell research aimed at understanding repairing spinal cord injuries or replacing malfunctioning brain cells in neurodegenerative diseases. It may also provide insights into other diseases, such as small cell lung cancer, which mistakenly make ne...

Breakthrough isolating embryo-quality stem cells from blood

...f their cytoskeletons. Watts explains that such an advance could have far-reaching consequences for medical treatments. "We could add significantly to our knowledge of stem cell biology toward developing cellular therapies," he says. The optical stretcher can already test 3,600 cells per minute. This is not...

Mouse with designer liver has enhanced glucose tolerance, insulin response

...were made available to the scientific community by advance posting online at the journal's website on April 10th. The liver plays a major role in the uptake of glucose from the bloodstream, its storage, and regulation. Insulin resistance in the liver is a crucial factor in the development of hyperglycemia a...

Important discovery about second most fatal cancer

...l team of medical scientists has made an important advance in our understanding of the second most fatal form of cancer in the industrialized world. Professor Jeremy R. Jass, who holds a Canada Research Chair in Gastrointestinal Pathology at McGill University in Montreal, and colleagues in Australia and Japa...

Structure-building cell signals also may influence learning and memory

...the May issue of Nature Cell Biology, published in advance at the journal's website on April 10th. While the study's results are not immediately applicable to treating disease, they pave the way for future experiments on the roles played by ephrins in memory, learning, and other nerve cell functions, and po...

Molecular messengers perform a crucial role in the ability of injured nerve cells to heal themselves

Weizmann Institute findings might advance search for new therapies for injured nerve fibers....ron. The scientists hope that these findings might advance the future search for new therapies for injured nerve fibers. ### The research team also included ...

15-year hunt finds cause of pseudothalidomide syndrome

... The discovery, which is reported in the April 10 advance online section of Nature Genetics, proves that genes behind very rare inherited diseases can now be found, offering excellent opportunities to strengthen understanding of craniofacial and limb development, health and disease beyond the rare disease i...

Butterfly migration could be largest known

...Valley in the last week of March could be just the advance guard of one of the largest migrations of the species on record, said Arthur Shapiro, a professor and expert on butterflies at UC Davis. "This may be the biggest migration of modern times," Shapiro said. Shapiro said he is getting reports of "billi...

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