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Tag: "adult" at biology news

Viral protein influences key cell-signaling pathway

...t five percent of them, the infection will lead to adult T cell leukemia or lymphoma (ATLL). ATLL is an aggressive disease characterized by a long latent period and the proliferation of T lymphocytes. The virus is spread by sexual activity, by contact with infected blood and by infected women to children t...

Stem Cell Research Shows Potential for Replacing Tissue Damaged in Heart Attacks

...r ES cells to replace damaged or diseased cells in adult tissues has caused extraordinary interest in their...cytes from ES cells can repair diseased or damaged adult myocardium in non-human models. This last question is being answered in collaboration with John Auch...

New component of the 'brakes' on nerve regeneration found

...e, however, was that p75 is not widely made in the adult neurons in which this inhibitory receptor complex ... revealed that TAJ/TROY is produced throughout the adult brains of mice. Also, they found that TAJ/TROY readily fits into the inhibitory receptor complex and...

Gene Therapy Cures Inherited Liver Disease In Rats

...tely cured long term with a single injection in an adult animal," said Dr. Brendan Lee, associate professor of molecular and human genetics and a Howard Hughes Medical Investigator at Baylor College of Medicine. Crigler-Najjar syndrome is currently treated by placing the person under special UV lights. It...

Single stem cells from bone heal a broken heart

... first report of endogenous cardiomyogenesis after adult human stem cell transplantation. Myocardial infarction and heart failure are associated with major morbidity and mortality and there are currently limited therapeutic opportunities for intervention. This study provides the first demonstration of a s...

Heart repair gets new muscle

...r Spoc cells) isolated from the skeletal muscle of adult mice can turn into beating cardiomyocytes in a test tube within days of isolation. When these cells are injected into mice with heart damage, they migrate to the damaged tissue and differentiate into cardiac muscle cells. Epstein and colleagues argu...

New insight into regulation of blood stem cells

...opmental Cell expands on previous studies by using adult animals to examine the role of a key gene known to be required for blood cell formation. Information gained from this research will be useful for future studies aimed at directing stem cell differentiation in a variety of potential therapeutic contex...

Birds brains reveal source of songs

...esounds with ever-new, imperfect variations of the adult songs. Gradually, the youngsters' songs become less variable and more true to the old standards. Some years ago, Bottjer had observed that disabling a young finch's AFP circuit stopped the learning in midstream. The bird still sings, but never learns...

Anti cancer virotherapy well tolerated in first human administration, research finds

...tinely in the community causing mild infections in adult humans. Previously the Shafren group has published research on CVA21 that showed success in specifically targeting and killing melanoma cells in mice . The virotherapy technique involves the specific targeting and killing of cancer cells through th...

Silence the gene, save the cell: RNA interference as promising therapy for ALS

...n may be necessary for the survival or function of adult human motor neurons, the Swiss researchers designed a gene replacement technology that allows the knock-down of all mutant SOD1 forms while permitting the expression of a normal type SOD1 protein that is resistant to RNA interference-based silencing....

Infants With Rare Genetic Disease Saved by Cord Blood Stem Cells

...faster correction of enzyme deficiencies than does adult bone marrow, she said. Stem cells from cord blood ...vel to the brain more rapidly than stem cells from adult bone marrow, and cord blood stem cells repair deficiencies in both the central and peripheral nervou...

Double triumph in stem cell quest

...oubts about the results. The technique requires an adult cell and an egg, and because in Hwang's experiment...ines of ESCs that are genetically identical to the adult donor. He calls the new cells stembrids. His claim stunned the audience. How, asked stem cell exper...

NIAID begins clinical trial of West Nile virus vaccine

... vaccine, which will be tested first in 15 healthy adult volunteers, was developed for human clinical studies by researchers at the National Institute of Allergy and Infectious Diseases' (NIAID) Vaccine Research Center (VRC), and Vical Inc., San Diego, based on an animal vaccine tested at the Centers for D...

One gene links newborn neurons with those that die in diseases such as Alzheimer's

... similar to other neurons that are not replaced in adult life? Or, in terms of which genes are "turned on,"...go, Nottebohm discovered new neurons being born in adult birds, overturning the conventional wisdom that all neurons in vertebrates are created by birth or s...

To sea or not to sea: When it comes to salmon sex, size sometimes doesn't matter

...cture that tiny male under the belly of a 20-pound adult female that's returned to spawn, Quinn says. He's almost as likely to be a "winner" as the full-size males that are releasing their sperm in a competitive frenzy as the female deposits her eggs. And the tiny male has avoided the harrowing journey ta...

Signs of aging: Scientists evaluate genes associated with longevity

...ntists observed that during the early and mid-life adult stages of daf-2 mutants, genes associated with met... sip-1 were more abundantly expressed in the aging adult worms as compared to the early and mid-life adults. These genes were also differentially expressed b...

Oldest cranial, dental and postcranial fossils of early modern European humans confirmed

...esence of multiple individuals, males and females, adult and immature with cranial, dental and postcranial elements, the Mladec assemblage becomes the oldest directly dated substantial assemblage of modern human remains in Europe. ...

New polysaccharide may help combat multidrug resistance in cancer

... hyaluronan as a structural and inert molecule. In adult tissues it plays two roles. First, it assists in tissue hydration and in biophysical properties such as resilience. Second, it forms a template to which matrix proteins attach and form important extracellular structural complexes." Hyaluronan also a...

Gene therapy cures inherited liver disease in rats

...tely cured long term with a single injection in an adult animal," said Dr. Brendan Lee, associate professor of molecular and human genetics and a Howard Hughes Medical Investigator at Baylor College of Medicine. Crigler-Najjar syndrome is currently treated by placing the person under special UV lights. It...

Brain May Be Less Plastic Than Hoped

The visual cortex of the adult primate brain displays less flexibility in respons... and one-half months after injury to the retina of adult monkeys. They found limited reorganization in the primary visual cortex. Their results contradict p...

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