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Tag: "administration" at biology news

Topical treatment shown to inhibit HIV and herpes simplex virus infection

...ge (CVL) fluid collected before and one hour after administration of a single intravaginal dose of PRO 2000 gel or a matched placebo gel. CVL specimens were tested for their ability to prevent HIV and HSV infection of susceptible human cells in culture. Levels of inflammatory cytokines were also measured as markers...

Emory Study Tests Bone Marrow Stem Cells to Improve Circulation in Legs

...rs' blood will be measuredbefore, during and after administration of the drug or placebo. Thestudy is randomized and blinded, which means that volunteers will notknow whether they are receiving the study drug or the placebo.The goal of the study is to determine if and how much GM-CSF willincrease the number of circ...

U of M researcher examines newly emerging deadly disease

...ior illnesses. Patients should also be given early administration of activated protein C (i.e., drotrecogin) in an attempt to minimize purpuric skin injury and to slow the inflammatory cascade before irreparable tissue injury occurs. In addition, because toxic shock syndrome is mediated by superantigens, it is poss...

Muscle-targeted gene therapy reverses rare muscular dystrophy in mice

...ited to muscle, they found. Moreover, intravenous administration of the muscle-targeted gene reduced the glycogen content of heart and skeletal muscle and corrected individual muscle fibers. The effect persisted for 24 weeks post-injection, the team reported. A second gene therapy strategy, in which the enzyme in...

Boosting HIV screening can increase survival and is cost effective

... Paltiel, associate professor of health and policy administration in the Department of Epidemiology and Public Health at Yale School of Medicine. "Our findings, coupled with those of our colleagues, firmly establish the great value of expanded screening." Paltiel and his team developed a mathematical model of HIV ...

Supercomputer Dedicated To Bioengineering, Computational Biology Installed

... to its many other features, Rocks simplifies many administration requirements. Within a few days of unpacking more than 400 boxes containing the Dell nodes, bioengineering researchers this week had modeled how electrical impulses trigger contractions in the heart of a pig. ...

Anti cancer virotherapy well tolerated in first human administration, research finds

...rence delegates that these findings suggested that administration of a single dose of CVA21 directly into a cancerous tumour was well tolerated. "Administration of CVA21 may be of potential therapeutic benefit in controlling the spread of melanoma," Professor Shafren said. CVA21 is one of a small group of natural...

Novel gene-silencing nanoparticles shown to inhibit Ewing's sarcoma

...h. "This is the first study to show that systemic administration of siRNA can inhibit disseminated tumor growth," said Siwen Hu, a postdoctoral fellow at Children's Hospital of Los Angeles and the University of Southern California, and one of the study's lead investigators. "We conclude that this novel delivery s...

'Smart drug' targets deadly brain cancer

...r. Galanis, "This could allow us to customize drug administration to the patients most likely to benefit from it, and in that way, improve care." A Smart Drug In their study, NCCTG researchers used an investigational drug that is not currently available for wide use. Known as CCI-779, or temsirolimus, it is a "sm...

Prescription Drug Patches Gaining Ground, Tackling New Therapies

Created as an alternate route of drug administration to improve patient compliance and reduce drug side effects, prescription skin patches are rapidly becoming an important healthcare product category. While quietly gaining market share for the treatment of chronic conditions such as angina, hypertensi...

NCI Researchers Confirm the Effectiveness of Immunotherapy Approach to Treating Melanoma

...tients. Toxicities related to the chemotherapy and administration of a high dose of IL-2 were easily managed. The results of this study prove that a combination of chemotherapy and infusion of autologous, stimulated, white blood cells can have an impact on metastatic melanoma tumors in patients who do not respond ...

Newest HIV drugs should be used with FUZEON(R)

...atives to support patients and physicians with the administration and use of FUZEON. ...

Recombinant DNA technology may enable oral, rather than injectable, delivery of protein drugs

...l of Pharmacy. This technology may allow for oral administration of drugs that previously could only be given by injection, notes Wei-Chiang Shen, Ph.D., professor and acting chair of the Department of Pharmaceutical Sciences. Shen, along with colleagues David Ann, Ph.D., professor of molecular pharmacology and to...

Novel live reporting system to track cells

...sion of ferritin in the inserted cells through the administration of TET. When they stopped the TET, the "switch" tu...ld be particularly beneficial in those cases where administration of contrast material is compromised by barriers, including embryonic development and the central ner...

Compound might defeat African sleeping sickness, clinical trial beginning this month

...'s ever been specifically developed for it." Oral administration is important for treating the disease which occurs in villages where it can devastate afflicted populations, he said. Small villages do not have access to clinics or trained staff that can give injections or administer drugs intravenously. "Immtech ...

Nicotine triggers the same brain reward circuitry as opiates

...e timing and context of opioid receptor antagonist administration are critical for determining the effectiveness of ...ported here, clinical studies designed to evaluate administration of opioid antagonists just prior to cues associated with smoking could lead to a more promising trea...

Engineered molecule amplifies body's immune response

...nst infectious diseases and cancer. Unfortunately, administration of interferon is costly and short-lived and has significant side effects. We simply reasoned that it might be possible to improve the benefits of interferon by enhancing the way it produces its beneficial effects. We therefore improved a molecule, kn...

Nose odors and mouth odors: The brain distinguishes

...ocolate odor, raising the possibility that odorant administration interacts with experience to engage unique brain regions and that olfactory referral induced by retronasal stimulation creates a differential reward context for food but not for non-food odors by signaling availability versus receipt of food," they c...

Monkeying around to improve organ transplantation

...t survival in three long-surviving animals without administration of additional immunosuppressive agents. This study shows for the first time that anergic T cells generated ex vivo suppress renal allograft rejection in non-human primates. This may be an approach that could be used in human transplant trials. Title...

Opiate cocktail may spare cells from morphine's dark side

...y, researchers report a new study showing that the administration of a drug cocktail containing morphine along with small doses of two versions of methadone, a related opioid drug, significantly reduced both tolerance and dependence in test animals. The work is reported by Li He and Jennifer Whistler of the Ernest...

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(Date:12/19/2014)... LaunchKey , the first decentralized mobile authentication and authorization ... era, today announced the close of $3 million in ... Metamorphic Ventures with participation from ENIAC Ventures, Crosslink Capital, ... has raised $4 million to date, and will use ...
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