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Tag: "administered" at biology news

Amgen introduces comprehensive financial assistance programs for cancer patients

...tes millions of dollars to independent third-party administered patient assistance programs to help reduce the financial burden for uninsured or low-income patients. These programs build on Amgen's Reimbursement Connection®, which has been addressing the provider community's reimbursement questions regarding A...

St. Jude test of bird flu vaccine proves successful

...Vaxfectin TM adjuvant. An adjuvant is an additive administered with a vaccine that has little effect by itself, but improves the response of the immune system to the vaccine. ...

Gene transfer using mutant form of good cholesterol cuts vascular plaque and inflammation

... cholesterol (bad cholesterol) that one day may be administered in childhood to provide lifelong protection against vascular inflammation and plaque. The gene therapy research was supported by grants from the National Institutes of Health, the Eisner Foundation, Entertainment Industry Foundation, Milken Family ...

Vaccine combined with short-term postexposure antibiotics protects monkeys from inhalational anthrax

Anthrax vaccine administered in combination with a short course of antibiotics completely protected nonhuman primates from inhalational anthrax, the most lethal form of the disease, according to scientists at the U.S. Army Medical Research Institute of Infectious Diseases (USAMR...

Restoring tamoxifen sensitivity in resistant breast cancer cells

...IBA in a form that is water soluble so it could be administered as a pill, the same as tamoxifen. If successful, this could set the stage for preclinical studies. ...

Insulin receptor stops progression of Alzheimer's disease

...n this study induced Alzheimer's with STZ and then administered treatment with three classes of PPAR agonists ?alpha, gamma and delta. All are found in various tissues and organs in the body, including the brain, and PPAR gamma is already FDA approved as a treatment for Type 2 diabetes, or adult-onset diabetes. T...

Cancer stem cells linked to radiation resistance

...stem cells present in the original tissue and then administered set doses of ionizing radiation to the cell cultures and to the mice. In both cases, the researchers observed a roughly fourfold jump in the number of glioma stem cells present in the tumor tissue following radiation treatment. Because ionizing ra...

Emotional control circuit of brain's fear response discovered

... Working with 19 healthy volunteers, the test was administered while participants underwent an fMRI scan. Based on neural activity, they identified activity in the rostral cingulate (rACC) region of the brain ?a region neuroscientists had not been previously able to define ?which turned on/off the amygdala's...

Highly concentrated botulinum preparation for cosmetic injections can result in severe illness

... clinical use. The physician working at the clinic administered 4 case-patients (including himself) 4 to 6 injecti...in taken from the same manufacturer's lot as toxin administered to the case-patients contained a toxin amount sufficient to kill approximately 14,286 adults by inje...

Therapeutic role found for carbon monoxide

... Since then, numerous studies have shown that when administered at low, non-toxic concentrations prior to such procedures as organ transplant surgery or balloon angioplasty, CO provides potent protective effects against organ rejection or blockage of the carotid arteries. But, with these latest findings, explain...

Neural stem cells lend the brain a surprising capacity for self-repair

...ain termed the subventricular zone (SVZ) when they administered a particular drug. The SVZ is known to be a site, or niche, that contains neural stem cells after birth. In newborn mice, loss of the genes left the SVZ "greatly disturbed," Jan said. Their results indicated that Numb and Numblike have two import...

A natural chemical found in strawberries boosts memory in healthy mice

...their attention to the novel object. Indeed, mice administered a single dose of fisetin could better recall familiar objects. In fact, fisetin worked almost as well as rolipram, a substance known to enhance memory. Memory loss caused by neurodegenerative disease occurs due to loss of neurons, a situation very...

Flu shot effective against drifted influenza, nasal spray vaccine less so

...f the New England Journal of Medicine, FluMist was administered to school children and the children were followed to see if they and their families had been protected against flu. The study's authors conclude that vaccinating children had some protective effect on the children and their families, confirming a not...

A new target for painkillers

... of painkilling medication. McIntosh says Vc1.1 is administered by subcutaneous (under the skin) injection. McIntosh hopes the new findings make it feasible to develop a painkiller based on RgIA that could be taken orally, but he believes that will take at least 10 years. McIntosh co-authored the stu...

Controlling antibiotics and antibiotic resistance in hospitals

...s fall into three categories (1) preventive, often administered before or during surgery; (2) empiric - prescribed before the physician knows the specific nature of the bacteria; and (3) targeted - prescribed after bacterial culture results identify the bacteria actually causing the infection. The study found ...

Intravenous gene therapy protects normal tissue of mice during whole-body radiation

therapy administered intravenously could be used as an agent to protect...age. In this study, we found that the same therapy administered intravenously also offers protection during exposure to whole-body irradiation." Dr. Greenberger add...

Hair-growth drug artificially lowers PSA levels in prostate cancer screening, study finds

...atment of male-pattern baldness. While Propecia is administered at 1 milligram per day, patients who take the finasteride drug Proscar for BPH get a five times higher dosage, 5 mg per day. "The impact of finasteride on PSA levels is significant," said Dr. Roehrborn. "This needs to be realized by all internists, f...

Encouraging results in pancreatic cancer research

...l have found that when a human protein, PNC-28, is administered to pancreatic tumor cells in animals, the tumors a... block the growth of pancreatic cancer cells. When administered over a two-week period in the peritoneal cavities of mice containing simultaneously transplanted tum...

Monoclonal antibody reduces exacerbations in asthmatics

...se, infusions of either infliximab or placebo were administered at weeks zero, two and six. "Treatment with infliximab reduced the number of moderate exacerbations in patients with asthma, as monitored by morning and evening use of an electronic spirometer incorporating a clinical diary," said Dr. Hansel. "Altho...

Researchers to study why dead zone returned to Lake Erie

...Atmospheric Administration joint institutes and is administered by the SNRE. The grant, funded by NOAA's Center for Sponsored Coastal Ocean Research, provides scientists $506,190 for five years. A dead zone is an area of oxygen starved water that cannot sustain aquatic habitat, said Scavia, who is also the dir...

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