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Tag: "administered" at biology news

Scientists discover that widely available drug also helps fight kidney disease

...studied the effects of rapamycin on mice. "When we administered rapamycin to mice with PKD and looked at their kidneys afterwards, we were absolutely amazed," said Weimbs. "The kidneys were smaller, had smaller cysts and had retained their function." "We have known the genetic mutations that cause PKD for over a...

Botox could help target resistant tumors for treatment

...sed with humans in clinical settings. The toxin is administered inside the tumor with very limited diffusion into normal tissues, which may limit the amount of damage to normal cells in proximity to the tumor. "This is the first experimental model demonstrating how Botox can affect the reaction of blood vessels ...

Basic research leads to a novel cancer therapy

...rket entry are expected in this year. Sunitinib is administered after diagnosis. A large number of further clinical studies has shown that Sunitinib has multiple effects on tumour cells and can thus be defined as a novel "multi-targeted" drug. Sunitinib is being tested now, as well, on patients with advanced for...

Gene-specific Ebola therapies protect non-human primates from lethal disease

...herapeutic approach in mice, whether the PMOs were administered before or after Ebola infection. Combination thera... pigs, where it appeared to be most effective when administered after infection. To further evaluate the efficacy of the three-PMO combination, four rhesus monkey...

UCLA scientists uncover mechanism of response to targeted therapy

...ancer cells or the angiogenesis inhibitor could be administered to cut off the blood supply to the tumor, stopping the flow of oxygen and nutrients that the tumor needs to survive. Standard of care for kidney cancer is almost always removal of part or the entire kidney, so that tissue could be tested for the mol...

New licensing agreement to maximize AIDS drug development

...nd other sexually transmitted diseases. CONRAD is administered through the Department of Obstetrics and Gynecology at Eastern Virginia Medical School (EVMS) in Norfolk, VA, with the main office located in Arlington, VA. www.conrad.org Cellegy Pharmaceuticals is a specialty biopharmaceutical company that devel...

All placebos not created alike

...de effects suggested to them even when nothing was administered to cause them. This study takes the first step away from examining the placebo effect as a generalized phenomenon to one investigating how it varies in specific clinical environments. Kaptchuk and his colleagues have initiated other National Instit...

Stem cell transplants improve recovery in animal models for stroke, cerebral palsy

...only utilized animal model for stroke, researchers administered a dose of 200,000-400,000 human stem cells into th... undesired side effects, and may be problematic if administered to patients for long periods of time. These results are consistent with those seen in other models,...

A step forward in the fight against bacterial infections

... the regulation of immunity. The Ghent researchers administered 10 times the lethal dose of LPS to the mutant mice...rferons. To verify this, Mahieu and her colleagues administered these interferons preventatively to the mice − which made the animals susceptible to LPS once ...

Traditional Chinese medicine for diabetes has scientific backing

...iterature as having a glucose lowering effect when administered to people with diabetes; yet, until now, its mode of action was unknown. Garvan scientist Dr Jiming Ye says: "Our studies in animal models of diabetes show that berberine acts in part by activating an enzyme in the muscle and liver that is involved...

Device effective in zapping the pain out of migraines

...s to be effective in eliminating the headache when administered during the onset of the migraine. The study, led by the Ohio State University Medical Center neurology investigators, was presented Thursday (6/22) at the annual American Headache Society meeting in Los Angeles . A subsequent study will examine t...

New GI technologies improve internal organ visualization

... a single dose of fentanyl as pre-medication, then administered propofol using the CAPS system and its dosing algorithm and safety shell--a control safeguard software program. Data was downloaded from the sedation device to a laptop computer to measure patient response throughout the procedure and adjust the sed...

Nicotine exposure during development leads to hearing problems

...seem to actually enhance cognitive processing when administered to adults, a finding that has also been shown in previous studies. The researchers found that in this study, nicotine appeared to enhance auditory function in the adult rats, but only if they had not been exposed to the substance during development. ...

Combating anthrax: Results of study published this month as researchers look for a better vaccine

...a clear relationship between the amount of vaccine administered and the subsequent immune response. The study was...or use in the United States. All vaccinations were administered intramuscularly. ...

A new look at the state of the oceans

... data centre represents a virtual institute and is administered by the Alfred Wegener Institute and the Centre for Marine Environmental Sciences. Aside from WDC-MARE, there are more than 50 other global data bases worldwide that serve as long term archives and provide information for science. PLANKTON*NET is fin...

Combined treatment extends life expectancy for lung cancer patients

...d treatment, brachytherapy radiation was typically administered within two hours of thermal ablation while external beam radiation was given within three to four weeks. Rhode Island Hospital may be the only hospital in the world to administer this combined treatment. The recurrence rate was much lower with the ...

Natural vitamin E tocotrienol reaches blood at protective levels

...f Neurochemistry. "We have determined that when administered orally, tocotrienol can reach concentrations needed to serve these dual protective functions," said Chandan Sen, professor and vice chair of surgery, deputy director of the Davis Heart and Lung Research Institute at OSU, and senior author of both stu...

New compound reduces stroke damage

...06 (also known as Tacrolimus or Prograf®) is often administered to patients receiving transplants to prevent organ...d a molecule that specifically inhibits FKBP38 and administered it to rats that were experiencing stroke symptoms. "We developed a lead compound that strongly inhib...

Compound in dairy products targets diabetes

... Heuvel. Early human trials indicate that when administered for longer than 8 weeks, CLA improves the body's misregulation of insulin and lowers the level of glucose in the blood in patients with adult onset, or Type-2 diabetes, the most common form of this disease. However, Vanden Heuvel cautions that ...

Patients to benefit from novel technology revolutionizing high-speed molecular imaging

...ety standards limit the radiation dose that can be administered for the purpose of diagnostic imaging," said Patton. "In addition to this limitation, the low efficiency of existing SPECT imaging technology in collecting radiation imposes very long acquisition times of up to a full hour and sometimes more," he add...

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