Convergent evolution of molecules in electric fish
... parts of these proteins relevant to human health, adds Zakon. "When natural selection is acting to cause changes in a part of a molecule, you know it's functionally important," he says. "Natural selection can start showing you the important parts of molecules. We took the evolutionary approach, which is...Protein found to control tumor growth in certain breast cancers
...tumorigenesis. "While still preliminary, our data adds another critical function to Nod1," Ulevitch said, "namely its ability to regulate the growth of estrogen-sensitive tumors formed by specific cell lines in immune deficient mice. The evidence uncovered in this study provides new insights into the ph...Radiotherapy advance points way to noninvasive brain cancer treatment
...calized in the nuclei of cancer cells." De Stasio adds that, for the treatment to be effective, gadolinium must be absent from normal cells and be present in the majority of the cancer cell nuclei. The first condition is well demonstrated by MRI, while the second was recently demonstrated using microscop...How nice, brown rice: Study shows rice bran lowers blood pressure in rats
...ls of unhealthy LDL cholesterol. The Tohoku study adds antihypertensive activity to the picture, along with a host of other biochemical markers that track blood glucose (implicated in diabetes), lipid profile, kidney function and the harmful effects of free radicals. For example, high levels of a marker...COX-2 inhibitors significantly reduce risk of cancer
...lyzing data from the other parts of the study, but adds that early results suggest that regular use of selective COX-2 inhibitors appears to provide about the same magnitude of protection from prostate, lung and colon cancer. "These results suggest strong potential for regular use of these drugs in cance...Scientists uncover rules for gene amplification
...ation would yield a homogenously-staining region." adds Vidhya Narayanan a Ph.D. student in Kirill Lobachev's lab and first author of the study. The findings can help researchers understand the cause of cancer in diseased individuals and also to potentially identify individuals who might be prone for can...Attacking cancer's sweet tooth is effective strategy against tumors
... surprising Achilles heel in cancer cells. It also adds to our sense of opportunity for new avenues of cancer therapeutics," said Stuart Schrieber, Morris Loeb professor and chair of the Department of Chemistry and Chemical Biology at Harvard University. As a tumor grows, cells crowd one another and may...Ritalin packs punch by elevating norepinephrine, suppressing nerve signal transmissions
...al areas of brain. Next steps "This experiment adds to our knowledge of what the drug is doing at the cellular level and gives us a springboard to other studies," Waterhouse said. "One question now is, how does the individual's perception of what is an important stimulus factor into the equation?" Re...Parkinson's disease mechanism discovered
...he cell's "post office," which modifies, sorts and adds the molecular addresses that designate the specific destinations in the cell where proteins are needed. Lindquist and her colleagues had conducted a genetic screen in yeast to discover genes whose activity affected the toxicity of alpha-synuclein. T...Viagra improves high altitude exercise performance up to 45% for some
...ryone, she said. The bigger picture This study adds to the scientific knowledge of what physiological factors limit performance at altitude, including the role that cardiac output plays, Friedlander said. For instance, physiologists don't know why some people have trouble at altitude and may develop i...For diseases, when it comes to sharing a home, only close relatives will do
...and how this competition occurs within the hosts," adds Koskella. To win host resources away from a non-relative, theory assumes the pathogens will increase exploitation of the host and thus cause more severe symptoms. However, if pathogens share the host most often with close relatives, this evolutiona...Corn waste potentially more than ethanol
...ducing electricity from steam exploded corn stover adds to the energy diversity of our portfolio," says Logan. "Electricity can be used to pump water uphill for later use, directly run light, heat and equipment or electrolyze water to create hydrogen." The Penn State researcher and colleagues have also...FSU biologists uncover mechanisms that shape cells for better or worse
...ization of the oocyte," Deng said. "That knowledge adds a pivotal link to our understanding of precisely how cell-to-cell communication occurs in this model system." In recognition of groundbreaking work to-date by the FSU scientists -- and to further the understanding of the mechanisms involved in cell...Schepens scientists are first to discover angiogenesis switch inside blood vessel cells
...or Schepens scientist, Dr. Andrius Kazlauskas, who adds that scientists have long suspected an "intracellular" switching process, but until now have known very little about it. "Current drugs focus on suppressing angiogenesis by inhibiting a mechanism outside the vessel cells, which involves the action of...Basic work on E. coli identifies two new keys to regulation of bacterial gene expression
...e study of gene expression in other organisms, and adds to the wealth of knowledge about E. coli contributed by scientists from the UW-Madison. "The kinds of processes that we study in E. coli happen in a wide variety of bacteria of medical, environmental and agricultural importance," notes Rick Gourse, ...New roles for growth factors: Enticing nerve cells to muscles
...uscle, blood and bone marrow cells. The Salk study adds on more job to an already long list. "Our study emphasizes that the nervous system does not necessarily rely on an entirely new set of molecules to govern axon navigation, but instead uses growth factors already involved in embryonic development in ...'Pinball protons' created by ultraviolet rays and other causes can lead to DNA damage
... a context is not yet understood. The UGA research adds important knowledge about how so-called "deprotonated" DNA base pairs work and could be important in creating "DNA wire." ...Airborne mold spores increase kids' risk for multiple allergies
...of different types of mold in the air we breathe," adds Melissa Osborne, a graduate of UC's environmental and occupational hygiene program and study lead author. "But because mold exists naturally in the outdoors, it's very difficult to completely remove mold spores from the air." Osborne conducted this ...Study shows pine bark naturally decreases severe chronic venous insufficiency
...not hold the weight of excessive blood, which then adds more pressure onto the next valve further downwards. Ultimately, the inability to prevent the liquid in the blood from seeping into the tissue is what causes edema, a common condition of CVI." Researchers at L'Aquila University in Italy conducte......res a volume of carbon worth $40,000 ?$200,000 and adds more storage space through growth, worth $2,000 ?$ 10,000 each year. Cappellato and Bohnert plan to study the park further, as well as expand their study to urban forests throughout Memphis. She will discuss her work during a poster session on land...