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Tag: "adds" at biology news

Bioartificial kidney under study at MCG

... immune system. The new device for kidney failure adds billions of kidney cells that can perform many of these important kidney functions. Human proximal tubule cells are collected from kidneys obtained by the National Disease Research Interchange, a nonprofit organization that provides researchers with ...

New binding target for oncogenic viral protein

...protein is part of a ubiquitin ligase complex that adds ubiquitin to proteins to mark them for destruction by the cell. Fbw7 recognizes a destruction signal on certain proteins that need to be degraded and brings them in close proximity to the enzymes that attach ubiquitin. The proteins recognized by Fbw7...

Lack of enzyme turns fat cells into fat burners

...rts become obese and develop type 2 diabetes."This adds another tissue or organ that helps out in the process ofenergy maintenance," said Wakil. "ACC2 is potentially a key enzyme inthe regulation of weight, obesity, and related problems."Wakil and his colleagues studied the oxidation of fatty acid andgluc...

Newly-discovered class of genes determines ?and restricts ?stem cell fate

...Pax3 is known to be involved in some tumors, which adds evidence to the stem-cell origin for some cancers. This theory proposes that many cancers may arise from normally scarce resident stem cells that grow uncontrollably, rather than from the vast majority of differentiated cells that make up organs wher...

Timing is everything: First step in protein building revealed

...r laboratory experiments that is clearlythe case," adds Lorsch. "Even if it isn't released completely in intactcells, our results would indicate that it must be very looselyassociated for translation [protein building] to begin."To monitor what was happening to eIF1, the researchers tagged it and arelated...

Another Look Finds Promising Proteomics Test is Not Biologically Plausible

...nt of Biostatistics & Applied Mathematics. He adds that this study “illustrates the need for researchers to set standards by which to conduct proteomics research,?meaning that protocols involved in these investigations should be common across laboratories so that results from one lab can be verified ...

New species from old data

...nt of Biostatistics & Applied Mathematics. He adds that this study “illustrates the need for researchers to set standards by which to conduct proteomics research,?meaning that protocols involved in these investigations should be common across laboratories so that results from one lab can be verified ...

Cracking the olfactory code in bees

...nt of Biostatistics & Applied Mathematics. He adds that this study “illustrates the need for researchers to set standards by which to conduct proteomics research,?meaning that protocols involved in these investigations should be common across laboratories so that results from one lab can be verified ...

Signaling protein builds bigger, better bones in mice

...nt of Biostatistics & Applied Mathematics. He adds that this study “illustrates the need for researchers to set standards by which to conduct proteomics research,?meaning that protocols involved in these investigations should be common across laboratories so that results from one lab can be verified ...

Genome-wide mouse study yields link to human leukemia

...rs found that methylation, a chemical process that adds methyl molecules to DNA, silenced a number of gene...aligiuri says much more work needs to be done, but adds that the identification of Id4 as a likely tumor suppressor gene gives clinicians another possible t...

Learning to fight an adversary that won't stay down

...eld solutions to the problem, says Dr. Davies. He adds that our understanding of the activity of microbes must extend beyond the newspaper headlines reporting outbreaks of these "superbugs," so that we can put the role of these organisms in the proper evolutionary perspective. This subject, and antibioti...

Novel Enzyme Shows Potential As An Anti-HIV Target

...ominently in this regulation is acetylation, which adds an acetyl group (a molecule made of oxygen, hydrogen, and carbon) to a molecule or protein. Histone acetylation was long thought to influence transcription by regulating the structure and function of chromatin, which is an assembly of proteins (mostl...

Researchers reveal the infectious impact of salmon farms on wild salmon

...stigate the degree of impact on wild populations," adds Krkosek. The authors concur that their findings point to a need to reconsider the premise of industrial scale fish farming in wild salmon habits. "There's a double bottom line here. The full ecological costs of industrial scale salmon farming must b...

Gene Vaccine Protects Mice Against Development Of Her2/neu Breast Cancer

...2/neu tumors from metastasizing, or spreading, but adds that thisnotion must be tested in human clinical trials.Lachman believes that the vaccine will address two additional safetyconsiderations “because it is built of RNA that cannot insert itselfinto the genome, and the possibility of autoimmunity to it...

A comprehensive response to HIV could prevent 10 million AIDS deaths in Africa by 2020

...2/neu tumors from metastasizing, or spreading, but adds that thisnotion must be tested in human clinical trials.Lachman believes that the vaccine will address two additional safetyconsiderations “because it is built of RNA that cannot insert itselfinto the genome, and the possibility of autoimmunity to it...

Newly Discovered Compound Blocks Known Cancer-Causing Protein

...r key player in the pathway, the Icmt enzyme. Icmt adds a chemical tag called a "methyl group" to Ras. This methyl tag enables Ras to be directed to its final destination in the cell, from where it can send signals for unchecked growth. "Ras needs to be at the plasma membrane in order to function," he sa...

Rats infected as newborns grew up vulnerable to memory problems during an immune challenge

...these responses is likely to cause problems." She adds that, "Memory impairment in wild animals would undoubtedly have severe implications for survival, for example remembering nest sites, food sites and predator vicinities, as well as for fitness, for example remembering territories and potential mate l...

NASA links nanobacteria to kidney stones and other diseases

...solve this puzzle, but we feel that we are close," adds Ciftcioglu. NB was discovered in the 1990s and has been found in the calcium phosphate centers of kidney stones. This novel agent has also been detected in related conditions, including Alzheimer's disease, heart disease, prostatitis, and some cance...

50-year-old Mystery Solved: Protein Tags Regulate Key Ion Channel

...atric Sciences at the University of Chicago. "This adds a new chapter to the book of how cells control ion channel function: reversible peptide linkage." Ion channels are in every cell in the human body. They are tightly controlled tunnels through the membrane barriers that hold in the cell's contents, s...

New component of the 'brakes' on nerve regeneration found

...ceptor member may be involved in myelin inhibition adds a new level of complexity to designing therapeutic strategies for treating CNS injury." They cited studies showing that TNF receptors are expressed in many types of cells in the CNS and are intimately involved in inflammatory responses that also play...

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