USC researchers determine mechanism of action of chemotherapy drug
...g's mechanism of action," Hacia said of the study, adding that it also may "provide support for the hypothesis that agents that disrupt metabolism and increase intracellular zinc levels have potential applications as anticancer therapeutics." ...New complete muscle grown in the lab
...selves in tubes nestled between the myoblasts. By adding fibroblast cells to the scaffold, the researchers were able to significantly boost the growth of the blood vessel network forming within the muscle tissue. Thanks in part to the stabilizing influence of the fibroblasts, the surface area covered by ve...Purdue scientists may have found key to halting spinal cord damage
...doctors to stop the chemical attack cycle as well, adding to the number of treatment methods available." The center was established in 1987 both to develop and to test promising methods of treatment for spinal cord injuries. The center uses its close affiliation with the Department of Veterinary Clinical S...Bad aftertaste? New sensory on/off switch may 'cure' bane of artificial sweetener search
...emblies that absorb therapeutic light and they are adding units to the structure. For instance, they added p...gton, D.C., Convention Center. She will talk about adding functionality to the group's supramolecular assemblies. Co-authors of the research are Matthew T. ...Virginia Tech group adds tools to DNA-targeted anti-cancer drugs
...emblies that absorb therapeutic light and they are adding units to the structure. For instance, they added p...gton, D.C., Convention Center. She will talk about adding functionality to the group's supramolecular assemblies. Co-authors of the research are Matthew T. ...Achilles heel of the herpes virus possibly found
...n of both human cells and susceptible pig cells by adding to cell cultures a synthetic peptide made to mimic the structure of a smaller region of the B5 receptor. This peptide looks like a functional region of B5 and apparently interferes with virus engaging of the cell receptor. The papers detail how the ...By creating molecular bridge, scientists change function of a protein
...ing protein function to the target new function by adding some intermediate functions followed by stepwise directed evolution of these intermediate functions. If done, it gives you the ability to create protein functions for any purpose you want -- as a catalyst to create new chemicals that might be useful ...Newest HIV drugs should be used with FUZEON(R)
... POWER 1 & 2 and TORO 1 & 2 studies, where adding FUZEON was seen to almost double the number of patients reaching undetectable, when combined with one of the latest boosted PIs such as lopinavir/r, tipranavir/r or TMC 114/r. Doctors underestimate significant "FUZEON effect" Surprisingly, of the 5...Insects, viruses could hold key for better human teamwork in disasters
..., collect and search for information," Gupta said, adding that "the resulting software systems can scale to networks with hundreds or thousands of first responders, as well as withstand unresponsive participants and poor communication channels. "This behavior is very similar to how rumors or fads spread in...Research shows smoking adds a decade to reproductive age of IVF patients
...king has a devastating impact. It is comparable to adding a decade to the reproductive age of a 20-year-old. This means it makes her the equivalent of a 30-year-old non-smoker in reproductive terms. "However, it also indicates that subfertile couples may help their chances of successful treatment by life-s...Software Tool for Converting Scientific Text into a Database of Functional Relationships
...onaries, and extract new types of relationships by adding or editing linguistic patterns. MedScan users can create information extraction pipelines with different output, set up regular automatic processing of upcoming content for selected sources, and integrate MedScan with other bioinformatics tools for f...A New Species of Monkey is Discovered in Tanzania: The First in Africa for More Than 20 Years
...a’s conservation efforts.? Butynski fully agrees, adding that, “This discovery is especially important because it not only expands the diversity of the genus Lophocebus from two to three species, it extends the geographic range of the genus 500 miles (800 km) to the south, thereby contributing much to ou...FDA Warns About Antipsychotic Drugs and Elderly
...he dementia population. The agency is considering adding a warning to the labeling of older antipsychotic medications because limited data also suggest a similar increase in mortality for these drugs. The review of the data on these older drugs, however, is still on-going. ...Bioelectronic ‘signatures?hold key to DNA mutations
...e, SNPs occur about once in every 1,000 DNA bases, adding up to 3 million potential individual differences across the human genome. Wang’s method allows for an accurate, ultra-sensitive, rapid and low-cost identification of these SNP variants. “The novelty of the approach is the combination of the nanocrys...Nano-bumps could help repair clogged blood vessels
...y worldwide, with sales of "vascular biomaterials" adding up to more than $1 billion each year. The research has been funded by the National Science Foundation. Webster's lab is affiliated with the Birck Nanotechnology Center and the Bindley Bioscience Center, which are in Purdue's Discovery Park, the univ...New Drugs For Bad Bugs: UF Approach Could Bolster Antibiotic Arsenal
...fessor of medicine at the University of Wisconsin, adding that until now, “many, many antibiotics that initially came out have either had their dosages changed because they were excessive or had them increased because they weren’t enough.?/p>...New component of the 'brakes' on nerve regeneration found
...y found a new component of that braking machinery, adding to understanding of the regulation of neuronal regeneration and of possible treatments to switch off the brakes on regrowth of spinal cord or brain tissue. The two groups--one group led by Jong Bae Park, Glenn Yiu, and colleagues from Children's Hos...Newly Discovered Compound Blocks Known Cancer-Causing Protein
...er to function," he said. "By preventing Icmt from adding a methyl group, we can effectively shut down Ras' ability to function, stopping it from sending signals for uncontrolled growth." Initial experiments showed that knocking out the Icmt protein using genetic targeting also inhibited Ras, so the scient...Nano-Probes Allow an Inside Look at Cell Nuclei
...the cells exchange their mitochondria," says Chen, adding that their technique paves the way for imaging a host of other long-term biological events. "The toughest part is getting inside the nucleus, and we have already cleared that hurdle." Chen and Gerion's research was published in the 2004, Vol. 2, No.......bind and form a complex, they help activate Akt by adding a phosphate group to a sequence of its amino acids (a process called "phosphorylation"). This process occurs not only in human cells but in other organisms such as the fruit fly. Finding this complex conserved in species as diverse as flies and huma...