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Tag: "addiction" at biology news

New research identifies gene important for nicotine's effects on the brain

...g which pathways are really important for nicotine addiction as opposed to other types of abuse. Picciotto's research used both genetically engineered mice with altered nicotine receptors and viruses that could block CREB function. She and her colleagues showed that one type of nicotine receptor was importan...

Smokers quit after damage to brain region

...y of its kind to use brain lesions to study a drug addiction in humans," Naqvi said. In the 1990s, Antonio Da...ddictions. The discovery of the insula's role in addiction opens new directions for therapies, Bechara said, including possible drugs targeted to a region that...

Morphine makes lasting -- and surprising -- change in the brain

...ntist Julie Kauer, may help explain the origins of addiction in the brain. The research also supports a provocative new theory of addiction as a disease of learning and memory. "We’ve added a new piece to the puzzle of how addictive drug...

Long-term narcotics use for back pain may be ineffective and lead to abuse

...ncerns clinicians have with patients developing an addiction to these medications," said first author Bridget Martell, M.D., assistant clinical professor of general internal medicine at Yale School of Medicine. "Our findings suggest that clinicians should consider other treatments with similar benefits but few...

Re-analysis of cigarettes confirms tobacco companies increased addictive nicotine 11 percent

... deliver sufficient nicotine to create and sustain addiction influences their selection and combination of design parameters." Cigarette smoking causes an estimated 438,000 premature deaths (or about 1 of every 5 deaths) annually in the U.S., and approximately 900,000 persons become addicted to smoking each...

OHSU lab finds meth receptor that could lead to therapy

...ew target for pharmaceutical therapy to treat meth addiction and also reduce the negative manifestations of its abuse. "Meth addiction is such a problem and we have nothing to treat it with except group support therapy," Grandy said. "...

Bioluminescence at the service of a novel cerebral imaging technique

...he context of a pharmacological approach regarding addiction to different drugs (alcohol, nicotine, cocaine, etc.)....

New compound prevents alcoholic behavior, relapse in animals by blocking stress response

...l barrier, closer to the day when the dark side of addiction is treated." The new findings build on previous work showing the effectiveness of blocking certain CRF receptors—proteins that bind CRF and make it active—in treating alcohol dependence in animals. CRF levels in the brain rise in the short term a...

In young mice, gregariousness seems to reside in the genes

... of new, more effective drugs to treat depression, addiction and autism. "We are quite confident it is genetic," says Jules B. Panksepp, a UW-Madison neuroscience graduate student and the lead author of the new study, which was conducted using two different strains of young mice, one gregarious in nature, t...

NIDA study identifies genes that might help some people abstain from smoking

...r toward tailoring individualized drug therapy for addiction based on an individual’s unique genetic makeup. ... marks a movement from identifying the genetics of addiction vulnerability to identifying the genetic basis of successful abstinence. This knowledge could impact...

New study examines 'brain's own marijuana'

...nships between stress, stress-related behavior and addiction using a combination of electrophysiological, pharmacological and neurochemical approaches. They believe this study also may lay the foundation for better pharmacotherapy for stress-related mood disorders. Wood is an associate professor in the Departm...

'Smart' mice teach scientists about learning process, brain disorders

...5 is heavily implicated in Alzheimer’s disease and addiction to drugs of abuse, so understanding how the enzyme affects the brain and behavior might aid in the development of new treatments for these and other conditions, Dr. Bibb said. The key in this study was being able to "knock out" the gene for Cdk5 ...

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