Cancer stem cells linked to radiation resistance
... proteins involved in the activation process. They added the drug before and after radiation treatment and measured the number of surviving cancer stem cells. They found that administering the drug before radiation did little to change the number of cancer stem cells, but giving the drug in conjunction ...Researchers reveal mystery of bacterial magnetism
...ng how the bacteria moved away from oxygen that we added to their environment," reports Dr. McRae Smith, a member of the team while a postdoctoral researcher at NRL, "we directly measured how much magnetotaxis helps." NRL researcher Dr. Paul Sheehan adds, "by mathematically modeling their motion, we deter...Age-related changes in DNA repair illuminate the connection between age and genetic damage
...al but hazardous process, often leaving missing or added bases at the point of repair. Cells possess a variety of methods for repairing broken DNA, and the cell's "choice" of how to repair a particular break can be critical. Some repair methods are simple but error prone, whereas the more accurate methods ...Wolves are suffering less from inbreeding than expected
... an important observation since if novel genes are added by introducing a new wolf from a nearby population, the positive effects will be maintained longer than previously estimated. - We think our results are relevant also for other threatened populations of carnivores. Such spe cies require large areas...Like a snail through the intestinal canal
...ayer to use. To achieve this, an adhesive layer is added to the mucus-like properties, which allows the device to be stuck to the layer of mucus. The ability to be attached to a surface covered with lubricant is a great technological challenge, because most adhesives normally only work on 'clean' surfaces....Paying attention sets off symphony of cell synchronization
...sic that represents a vivid conscious experience," added Ken Paller, professor of psychology at Northwestern and co-investigator of the study. ...Hard-wiring the fruit fly's visual system
...es," said Bellen. "In vertebrates, complexity is added because of the challenge of millions of neurons having to make billions of precise connections. You have to work with a gross topological map first, and neuronal activity refines this map later," he said. The study adds to an ongoing debate about ...Bird flu vaccine additive may stretch supply
... doses as low as one-quarter of the norm when they added a chemical mixture known as MF59. The research is published in the November 1 issue of Clinical Infectious Diseases, now available online. MF 59 is an adjuvant--a substance that increases the immune system's ability to respond to a stimulus. For t...A simple feedback resistor switch keeps latent HIV from awakening
...cetyl group--a functional group that is frequently added to (acetylation) or removed from (deacetylation) proteins to modify their properties--and that deacetylation inactivates Tat. Based on the known kinetics of both acetylation and deacetylation, the authors postulated that a resistor might exist in the...How does a zebrafish grow a new tail?
... we might be able to promote regeneration." Moon added that, because the same genes for turning on and turning off growth and development are found in humans, and drugs exist that can regulate this pathway, the findings are directly relevant to future testing of whether scientists can increase the capaci...H9N2 avian flu vaccine paired with adjuvant provokes strong human immune response at low doses
... S. Fauci, M.D. An adjuvant is a substance that is added to a vaccine to boost the body's immune response to the vaccine's antigen. "In the event of an influenza pandemic, adjuvanted vaccines could provide a way to extend a limited vaccine supply to more people," he adds. In 1999, two children in Hong Ko...Microcapsules like it hot and salty
...al capsules at room temperature. If salt is now added to the capsule solution, the electrical charges are neutralized and the capsules shrink again, the wall thickening as described in the first example above. "By combining simple materials available in any kitchen, we can vary the properties of the wal...MIT finds most complex protein knot ever seen
...quence that allowed a protein to form the knot was added or deleted. The third author on the paper is Mehran Kardar, an MIT physics professor. The research was funded by the National Science Foundation and the German Research Foundation. ...Recycled paper and compost could both be key tools to control plant disease
...le when the green and recycled paper composts were added to peat. Peat is used by many growers as it provides a clean and uniform material that is suitable for plant growth ?but its very cleanliness makes the plants growing in it susceptible to quickly spreading plant diseases. In contrast compost contain...Viral marker of human migration suspect
...ether geographically, she explains. Shackelton added that if the co-evolution of the virus and human populations were as strict as previously thought one would not find so many differences in the family trees of the virus and humans. Researchers also said that this study and others by the group sug...MIT nanoparticles may help detect, treat tumors
...ially is being used to study breast tumors. Bhatia added that it eventually may be applied to many different types of cancers and to study the "triggers" that turn a benign mass in the body into a cancerous tumor. Nanoparticles also hold the promise of carrying medicines that could kill cancer cells, repla...Solved: The mystery of flesh-eating bacteria's relentless attack
...ococcus destroyed interleukin-8. But when the team added the SilCR protein to the growing bacteria, the interleukin-8 survived. "The amount of interleukin-8 that survives is inversely related to how much SilCR there is in the culture," said Hanski. This may be one reason why some strains are less virule...Jefferson scientists identify gene mutation potentially involved in breast cancer initiation
...s enough to cause mammary tumorigenesis. Now we've added another link: inactivation of caveolin as the first initiation step." The team found that cyclin D1 activity in human breast cancer samples was increased, specifically after estrogen treatment. "In essence, we have created a preclinical model in w...Researchers find that bumblebees' flower choice matters
...nts. To investigate her hunch further, Flanagan added a third wetland species to the garden ?a native plant known as "great blue lobelia." So far, the bees continue their strong attraction to purple loosestrife. "This preference for purple loosestrife or other exotics could threaten reproduction of na......to be tested in human patients, Smith said, but he added that his team believes the technology is ready for clinical trials. The Duke team in 1987 developed the first-ever 3-D ultrasound scanner for imaging the heart in real time from outside the body. As technology enabled ever smaller ultrasound arrays...