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Cellular message movement captured on video

...m the inner membranous lining of a cow aorta. They added genetically engineered proteins tagged with red and green fluorescence markers to the bovine aortic endothelial cells, grew them in tissue culture, and filmed them while they passed fluid across the cells’ surface in a simulation of flowing blood. Wi...

Brain inflammation may be friend, not foe, for Alzheimer's patients

...s in Alzheimer’s disease is not an ideal therapy,” added Shaftel. “This might hinder processes that are beneficial and part of the body’s adaptive response to fight plaques.” The new findings hinge on a very special mouse that Shaftel spent three years creating with the guidance of his adviser, M. Kerry...

Soils offer new hope as carbon sink

...same when applications of nitrogen fertiliser were added to both the agrichar and the control plots. "Fo...the trial. "Soil biology improved, the need for added fertiliser reduced and water holding capacity was raised," he said. The trials also measured gases ...

How sneaky HIV escapes cells

...ld says. In one experiment, Gould and his team added chemicals to normal human cells that force nearby ...get them sent out of the cell in exosomes. If they added a tether to force naturally-clumping proteins inside the cell to the membrane, the proteins met a si...

Pesticides choke pathway for nature to produce nitrogen for crops

...op yield per unit of synthetic nitrogen fertilizer added and also a significant decline in overall symbiotic nitrogen fixation. The most common explanation for the observations is an overuse of agrichemicals applied to legume crops. That practice sets up "a vicious cycle," Fox said, because it reduces a...

Studies to find better ways to preserve human eggs, ovarian tissue under way

... to protect cells from the hazards of freezing are added before taking tissue from the refrigerator temperature of 4 degrees Celsius to minus 80 degrees Celsius over two- and one-half hours. Later, liquid nitrogen takes it to minus 196 degrees “You put it in a control-rate freezer that takes down the te...

Research shows cord blood comparable to matched bone marrow

...’ HLA types match as closely as possible. Wagner added that increasing the inventory will increase the chance of finding donors for ethnic and racial minorities currently underrepresented in volunteer marrow registries worldwide. While the study showed that umbilical cord blood took longer to rebuild...

Researchers shed light on shrinking of chromosomes

...n earlier phases of division. When the researchers added chemicals to the cell to block the late condensation, more separation defects appeared. “Sometimes chromosomes get stuck and cannot be fully separated by the spindle that normally distributes them into the daughter cells,” says Felipe Mora-Bermúdez...

Massive herds of animals found to still exist in Southern Sudan

... oil in the Sudd that is harming the environment,” added Elkan. “Industrial permits have been awarded over much of the migration corridors. Widespread automatic weapons used during the conflict are now being used by unauthorized individuals for poaching and commercial, unsustainable hunting. The internatio...

Researchers reveal structure of protein altered in autism

...ts seen in patients with autism,” said Taylor. He added that synapse formation and maintenance occurs early in development when the infant brain is still plastic and formative. Therefore, by understanding the structural mutations that affect neurotransmission during development, new leads into drug thera...

Human genetic 'deserts' are teeming with significant life

...with a gene knock-out or knock-in, where genes are added or deleted from a model organism in order to study the effect of therapies, he says. “It appears that the same nucleotide [the structural unit of DNA and RNA] on the genome can carry out a number of different, sometimes simultaneous, functions.” ...

Helping chlorine-eating bacteria clean up toxic waste

...alococcoides needs vitamin B-12, so the vitamin is added to cultures that are injected into cleanup sites. The bacterium also grows better in a mixed community with other kinds of bacteria. "There are some factors it needs from other organisms, and we don't know yet what they are," she said. Her laborat...

Ice Age extinction claimed highly carnivorous Alaskan wolves

...hed cats, a Smithsonian-led team of scientists has added one more: a highly carnivorous form of wolf that lived in Alaska, north of the ice sheets. Wolves were generally thought to have survived the end-Pleistocene extinction relatively unscathed. But this previously unrecognized type of wolf appears to ...

Antarctic icebergs -- Hotspots of ocean life

...l climate models that need to be further studied,” added Smith. To understand the icebergs’ complex impacts, the multidisciplinary team of researchers carried out the most comprehensive study ever done of individual icebergs and their immediate environment, taking a wide array of measurements – physica...

Modified mushrooms may yield human drugs

...ed small pieces off the mushroom's gill tissue and added it to a flask containing the altered bacterium. Over the course of several days, as the bacterium goes through its lifecycle, it transfers a portion of its plasmid out of its cell right into the mushroom cell, and integrates the introduced gene in...

New vaccine prevents CMV infection and disease in mice

...mmune system to not be tricked by the virus.” She added that the next step is to apply this strategy to create a vaccine for use in humans. CMV is a virus that, while carried by the majority of adults in the United States, can remain dormant for years, if not the lifetime, of a healthy individual. How...

Ants show us how to make super-highways

...of the potholes and follow their nest mates home," added Powell. "Broadly, our research demonstrates that a simple but highly specialised behaviour performed by a minority of ant workers can improve the performance of the majority, resulting in a clear benefit for the society as a whole." Their experime...

Researchers use MRI to predict recovery after spinal cord injury

... decompressive surgery," Dr. Fehlings said. He added that MRI should be performed on all patients with acute SCI whenever feasible as it provides information with prognostic value and serves to guide the clinician to optimize clinical care....

Extra-aggressive form of idiopathic pulmonary fibrosis identified

...tial Lung Disease at the University of Pittsburgh, added that this research highlighted the need to collect as much information on patients with IPF as possible. "We are only now starting to really understand the disease and characterize it," he said, "therefore, it is critical for patients with the diseas...

Gene expression patterns predict rapid decline in idiopathic pulmonary fibrosis patients

...valuate the effectiveness of potential therapies," added Talmadge E. King Jr., M.D., chief of medicine at San Francisco General Hospital and an internationally renowned expert in research and management of pulmonary fibrosis....

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