Therapeutic prospects beyond Vioxx
... cardiovascular risk, it would also be expected to add to the risk of stomach problems, undermining the reason for choosing COX-2 inhibitors in the first place." A surprising finding came when the investigators turned to a drug target that might substitute for COX-2 ?an enzyme called microsomal prostagl...Mice lacking social memory molecule take bullying in stride
...MH director Dr. Thomas Insel. "These new findings add to a growing literature on the molecular basis of social behavior, helping us to know where as well as how social information is encoded in the brain." The results reveal neural mechanisms by which social learning is shaped by psychosocial experie...St. Jude projects 90 percent cure rate for ALL
...inst the proteins made by genes linked to ALL will add to the options for treating this disease. "Multiple breakthroughs at St. Jude and elsewhere have transformed ALL from a virtual death sentence into a disease that children can increasingly be expected to survive with minimal side effects," Evans sai...Two NIH initiatives launch intensive efforts to find roots of common diseases
...ata analysis, and patient management expenses will add to these basic costs. It is important to note, however, that these costs are a small fraction of what has already been invested in enrolling these study subjects, examining them, carrying out extensive laboratory investigations, and collecting their ...Removing DNA repair gene causes metabolic syndrome
... "What we think this publication is going to do is add one more complexity to the potential mechanisms by which you could get to disease," he said. ...NHGRI announces new sequencing targets
..., deletions and inversions. The second plan will add DNA sequence to existing draft sequences of a number of primate species and add additional sequence information in regions of high biological interest within those genomes. The inc...Wisconsin scientists find a way to make human collagen in the lab
... to precisely manipulate the lengthy molecules and add elements to collagen that confer new abilities. "We can make collagen that duplicates nature exactly, but we can diverge from that when it is desirable," says Ronald T. Raines, a UW-Madison professor of biochemistry who, with postdoctoral fellow Fra...'Word-vision' brain area confirmed
...avor of the existence of the VWFA that will surely add fuel to the debate." He concluded that "The single case study…provides compelling evidence that the VWFA plays a causal role in the chain of neural events that underlie normal reading." ...Lactic acid not athlete's poison, but an energy source - if you know how to use it
...en in UC Berkeley's Exercise Physiology Laboratory add one of the last puzzle pieces to the lactate story and also link for the first time two metabolic cycles - oxygen-based aerobic metabolism and oxygen-free anaerobic metabolism - previously thought distinct. "This is a fundamental change in how peopl...Bringing the zoos to the zebras
...o Zoo, and one from Minnesota Zoological Park will add their special expertise to the Grevy's Zebras project. They will be able to share first-hand knowledge of Grevy's zebra conservation in captivity, and will take home valuable experience with zebra behavior and habitat needs in the wild. Earthwatch ...World faces challenge as life expectancies lengthen, scientist says
...to just above 2:5. Increased boomer lifespans will add an alarming extra weight to an already sagging system. Factoring in increased lifespans, Tuljapurkar calculated that current forecasts for dependency ratios could fall short by a factor of two--meaning that in America, the ratio will actually quadrup...Duck-billed dino crests not linked to sense of smell
...proximately the size of a human fist. The findings add weight to two currently popular theories: that the crests were used to create resonant sounds to attract mates or warn of predators, or that they were used for visual display in mate selection or species recognition, similar to feather crests in some...Scaled-down genome may power up E. coli's ability in lab, industry
...s that slice a space like a loaf of bread can also add slices one at a time," Brown said. According to Brown, the groundwork for this research was laid about 20 years ago when scientists first learned about the genes that regulate embryonic development in the fruit fly. She said one question that many s...K-State researchers study gene regulation in insects
...s that slice a space like a loaf of bread can also add slices one at a time," Brown said. According to Brown, the groundwork for this research was laid about 20 years ago when scientists first learned about the genes that regulate embryonic development in the fruit fly. She said one question that many s...Frog’s ear canal may provide insights for understanding human hearing loss
..., and co-author of the study. "In addition, we now add amphibians to the small group of vertebrates (bats, whales and some rodents) that use ultrasound for communication. This study may provide a clue for understanding why humans have ear canals: to improve sensitivity to high-frequency sounds." Amolops...Portable cocaine sensor developed at UC Santa Barbara
..., explained Plaxco, and some cocaine manufacturers add a chemical to block the color change. "Our sensor can detect cocaine no matter what they have cut it with: powdered sugar, flour, or the coffee that is sometimes used to mask the smell from dogs." At this point the new sensor detects cocaine in the ...Hot-spring bacteria flip a metabolic switch
...which probably powers N2 fixation. "These results add to our understanding of microbial mats as complex, integrated communities that are exquisitely adapted to life in the tough hot spring environment," Grossman commented. "There may be several different organisms living in a given mat, but it seems tha...Poison + water = hydrogen. New microbial genome shows how
...en, mix in a bit of poisonous carbon monoxide, and add a pinch of hydrogen gas. It sounds like a recipe for a witch's brew. It may be, but it is also the preferred environment for a microbe known as Carboxydothermus hydrogenoformans . In a paper published in the November 27th issue of PLoS Genetic...... about the process they used was that they did not add growth factors to the culture medium; the goal was to prevent the cells from differentiating prematurely. By doing so, the scientists discovered that the two cell lines were different in the expression of typical stem cell markers. The researchers th......pathogens are essentially lipid parasites. So, to add insult to injury, Chlamydia apparently lives on our fat. Lipid droplets are fat-rich structures found in all eukaryotic cells. In humans, lipid droplets are abundant in adipocytes, our professional fat storage cells, where they have traditionally be...