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Two-faced protein can stop metastasis or promote it, researchers say

...ue as it does in laboratory cell culture, and they add that other "pathways" are likely involved in the transition to metastasis. But if the results continue to hold up, "it might be therapeutically possible to selectively shut down the pro-invasive function of p120 on mesenchymal cadherins while keeping...

Hospital-acquired infections -- Inevitable?

...supplement demonstrates that the belief itself may add to the risk and it's actually the process of care that drives the current epidemic. "Despite all of our hard work, medical care can never be error free," commented Dr. Nash about the widespread beliefs about HAI. "What we must strive for is care th...

Walking not enough for significant exercise benefits

...ogram, but to increase the effectiveness, one must add some intensity or "huff and puff" to their exercise. Across your day, while you are achieving those 10,000 steps, take 200 to 400 of them at a brisker pace." "You've got to do more than light exercise and move towards the inclusion of regular modera...

Zinc plays important role in brain circuitry

...te neuronal signaling in the brain and spinal cord add a new key player: zinc. By engineering a mouse with a mutation affecting a neuronal zinc target, researchers have demonstrated a central role for zinc in modulating signaling among the neurons. Significantly, they found the mutant mouse shows the sam...

Sunflower speciation highlights roles for transposable elements in evolution

... eukaryotic genomes. The new findings not only add an interesting twist to the origin of new sunflower species through hybridization, but also suggest that the sunflower system may emerge as an excellent model group for studying the natural forces influencing the activation and proliferation of trans...

Study offers window into human behavior, brain disease

...s die in early Alzheimer's disease. "We hope to add von Economo neurons to that list," says Seeley. "It's a pretty important list to fill in, but for FTD there just hasn't been a good candidate until now. We think we've found it, and that is the most exciting part of the discovery for those of us who ...

H9N2 avian flu vaccine paired with adjuvant provokes strong human immune response at low doses

...us Diseases. "The results of this clinical trial add to the growing body of information demonstrating the potential value of adjuvanted avian influenza vaccines," says NIAID Director Anthony S. Fauci, M.D. An adjuvant is a substance that is added to a vaccine to boost the body's immune response to the ...

Halving daily cigarette quota has no health benefit

... significantly cut their risk of early death. They add that people may be misled if they are advised that cutting back will help them stave off disease....

Recycled paper and compost could both be key tools to control plant disease

...Professor Ralph Noble's latest research appears to add another ecological benefit. Early results from trials with conifers using compost made from paper waste shows that it is providing much the same disease suppressing effect as green compost made from plant waste. This provides an obvious additional c...

Jumping gene could provide non-viral alternative for gene therapy

...ines, including three human ones. "If we want to add a therapeutic gene, we can put it within the transposon and use it to deliver the gene into the cell," says Dr. Joseph M. Kaminski, radiation oncologist at the Medical College of Georgia Cancer Center and a corresponding author on research published ...

Inheriting a tendency to brain infection

...other and with the environment in subtle ways that add up to an overall predisposition or resistance. However, Michael Levin, professor of pediatrics and international child health at Imperial College, London, does not think the two theories are mutually exclusive. "We strongly suspect that rare, hi...

Iowa State researchers improving plastics made from corn and soy proteins

...traight loop. That's what happens when researchers add some glycerin ?a byproduct of biodiesel production...in a track. Senti said biodegradable plastics that add rigidity to the company's product would be very useful in outdoor applications. And so the company w...

A cleaner, greener rice industry

...anize another workshop in Malaysia to evaluate and add indicators, especially on the socioeconomic dimensions of rice production. This, we hope, will allow ASEAN members to much better assess the impact of environmental problems, especially in comparison with each other. "This is an exciting initiative ...

The secret lives of sea slugs

...aviors and the sensory cues that trigger them also add exciting new context for scientists studying them under experimental conditions and provide information that cannot be obtained in laboratories. The study sheds light on the sea slug's navigation, feeding, mating, and egg-laying behavior, and confir...

New study reveals structure of E. coli multidrug transporter protein

...Determining the structure of this transporter will add significantly to our general understanding of the mechanism of drug transport through the cell membrane and provide the structural basis for how these proteins go about selecting specific drugs to expel." Multidrug resistant bacterial infections rai...

Researchers find protein that silences genes

...ough only dreams, at present, these sorts of ideas add to the excitement surrounding the field of epigenetics. The Big Turn-Off For many years biologists thought that gene silencing in nucleolar dominance was a result of one set of ribosomal RNA genes being selectively turned on. But in 1997, Pikaar...

Just like us, social stress prompts hamsters to overeat, gain weight

...re and gain weight, but because, like humans, they add fat to their abdomens -- visceral fat. Visceral fat is particularly unhealthy because it affects the internal organs and is associated with diabetes, cancer and other serious illnesses, Bartness said. Bartness' team began a second study to determine...

Study identifies substances in grapefruit juice that interact dangerously with some drugs

...furanocoumarins. "Finally, it may be possible to add furanocoumarins to formulations of certain drugs that tend to be poorly or erratically absorbed to improve their oral delivery." ...

Immune system police learn early and sometimes badly

...upus, arthritis and type 1diabetes. Or, they might add regulatory T cells to improve the mix in people who already have some bad police. "We need some of the regulatory cells more than others," says Dr. Ignatowicz. "We probably need more of the ones that recognize autoantigens on the pancreas and we ne...

Federal testing for mad cow disease a failure, law review editor says

...d news reports that the cost of such testing would add only6 to 10 cents to a pound of beef. His article further warns of poor oversight of cattle feed. In particular, the slaughterhouse practice of "rendering," or recycling dead cows and sheep into protein for cattle feed, is believed to be widespread...

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