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Tag: "acute" at biology news

Old memory traces in brain may trigger chronic pain

...hows up in the prefrontal cortex. By contrast, the acute sensory pain of the burned finger appears in the sensory part of the thalamus. Apkarian also found that the longer a person has been suffering from chronic pain, the more activity in the prefrontal cortex. He was able to predict the years of thei...

Largest synthetic gene ever built offers insights into anti-malarial drug resistance

...ible for about 1 million deaths out of 300 million acute cases of infection each year. Most of these deaths occur in young children living in sub-Saharan Africa. Roepe and his collaborators at Georgetown University, in collaboration with investigators at the National Institutes of Health, described in ...

Research shows cord blood comparable to matched bone marrow

... children younger than 16 who had the diagnosis of acute lymphoblastic leukemia (ALL) or acute myeloid leukemia (AML)....

Clot-dissolving agent may be beneficial in treatment of severe frostbite

... patients who are admitted to our institution with acute frostbite,” the authors write. “Candidates for this therapy are patients who present with severe frostbite as suggested by full-thickness tissue involvement, hemorrhagic blisters and abnormal perfusion on either angiogram or pyrophosphate scanning. I...

Researchers use MRI to predict recovery after spinal cord injury

...ihood of full or partial recovery of patients with acute spinal cord injuries (SCI), according to a study p... that MRI should be performed on all patients with acute SCI whenever feasible as it provides information with prognostic value and serves to guide the clini...

Cytomegalovirus exacerbates atherosclerosis through an autoimmune mechanism

... genetic influence. However, it is well known that acute cardiovascular events may happen without the prese...en shown to play an important role in the onset of acute cardiovascular events. The online, open-access PLoS ONE publishes a new study on the relationsh...

Detecting cold, feeling pain: Study reveals why menthol feels fresh

...l receptor TRPM8 -- provides a target for studying acute and chronic pain, as can result from inflammatory or nerve injury, the researchers say, and a potential new target for treating pain. "By understanding how sensory receptors work, how thresholds for temperature are determined, we gain insight into...

Scripps research team sheds light on long-sought cold sensation gene

...ld plate. Cold temperature clearly reduced the acute pain felt by control mice as shown by a reduction ...contrast, TRPM8-deficient mice did not receive any acute pain relief from the cold plate suggesting that cold activation of TRPM8 can mediate some of the ana...

Keeping the immune system from starting a 'food fight'

...tein enriched in fat cells, called STAMP2, develop acute inflammation in deep pockets of visceral fat. The ...rrant inflammatory responses to both nutrients and acute inflammatory stimuli, they reported. Similarly, they showed that the visceral fat surrounding the...

Nitric oxide: Key to cardiovascular and pulmonary function and drug effectiveness

... such as beta adrenergic receptor agonists used in acute heart failure or in inhalers for asthma, lose their effectiveness over time. Nitric oxide is a molecule produced by the body that controls many functions, including the contraction or dilation of blood vessels. New experiments conducted by Duke U...

Cancer patients monitor fatigue in real time

...ker said. "For example, an adult diagnosed with acute myelocytic leukemia may seek medical care because of the extreme fatigue," Hacker said. "Cancer can cause fatigue directly or indirectly by spreading to the bone marrow, causing anemia and by forming toxic substances in the body that interfere with n...

Study offers clues to 'Broken Heart Syndrome'

...ent. All patients had ECG changes suggestive of an acute coronary syndrome, a term that encompasses both he...es in the motion of the heart. One patient died of acute heart failure. The good news is that most patients who survived the first 48 hours had a steady ...

Hepatitis E takes a piggyback

...V, which is found worldwide, can potentially cause acute hepatitis in humans. So monitoring infection rates could help protect meat processors and vets. The disease can be transmitted by drinking water contaminated with faeces as well as by eating pork: uncooked wild boar liver is one Japanese delicacy tha...

Herpes infection may be symbiotic, help beat back some bacteria

...sociated herpes virus. During an initial period of acute infection, many of these viruses cause symptoms, s...tudies of how mouse herpes viruses transition from acute to latent infections, Virgin made a discovery that piqued his interest in the possibility that laten...

The quest for an effective HIV vaccine presents new possibilities, challenges

..., caused a reduction in virus levels following the acute stage of infection, or produced some combination of these effects. In many of these animals, disease progression was also delayed. Based on the scientific evidence, several questions remain, say Drs. Johnston and Fauci: Can a vaccine that does no...

Leukemia drug turns mini-molecules up, cancer genes down

...earch shows that a form of vitamin A used to treat acute promyelocytic leukemia induces changes in an unusual class of small molecules called microRNAs (miRNAs) in the leukemic cells. The study also shows that three of these miRNAs inhibit the action of two genes important for cancer development, helping ...

NIAID expands capability for influenza research and surveillance

...itor for evidence of the reemergence of the severe acute respiratory syndrome (SARS). Additionally, the researchers will explore strategies for controlling influenza outbreaks in agricultural settings. University of California at Los Angeles (principal investigator—Dr. Scott Layne) UCLA investigators w...

Major gene study uncovers secrets of leukemia

...ions that contribute to the formation of pediatric acute lymphoblastic leukemia (ALL), the most common cancer in children. The discovery not only suggests novel methods for treating pediatric ALL, but also provides a roadmap for the identification of unsuspected mutations in adult cancers. ALL is a tum...

Power-boosting signal in muscle declines with age

..., mitochondria production. The treatments included acute exposure to an AMPK-stimulating chemical, chronic exposure through feeding of another chemical that induces AMPK by mimicking an energy shortage, and exercise. In every case, older rats showed a decline in AMPK activity compared to younger animal...

Better assessment of transfusions could save blood

...table, critically ill patients without evidence of acute bleeding....

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