For first time, brain cells generated in a dish
...ugh a method called live-cell microscopy, so we've actually witnessed the stem cell give rise to new neurons. ...cess "neuropoiesis." "The exciting part is we are actually using methods that researchers involved with hematopoiesis used," Scheffler said. "Those researchers...Secrets to antibody's success against West Nile Virus surprise scientists
...at preventing the virus from binding to host cells actually turn out to be worse at treating infection? The key may lie in a theory known as antibody-dependent enhancement (ADE) of infection, which has been observed in test tube studies of dengue virus and may be important to the onset of dengue hemorrhagic f...Bitter or sweet? The same taste bud can tell the difference
...rocedure uses fluorescent light to let researchers actually see the peptides under a microscope. They initially found that NPY is expressed in only a subset of taste bud cells. Yet every cell that expressed NPY also expressed CCK. "That surprised us, too," Herness said. "It may be that these cells release b...Crisis in African fish supplies looms, experts warn Africa leaders
...is the only world region where fish consumption is actually falling. "The main reason for this decline is the stagnation in capture fish production combined with a fast-growing population," says WorldFish Center Deputy Director-General Patrick Dugan. The situation also threatens one of Africa's leading sour...Tagging pathogens with synthetic DNA 'barcodes'
...eated probes consisting of nanoscale bars of metal actually etched with conventional bar codes. Since then, most molecular tagging devices have been referred to as "barcodes," even though there are no bars involved. The researchers have tested their system using samples containing various combinations of E. ...Leptin-signaling Protein Maintains Normal Body Weight And Energy Balance In Mice
...is the only world region where fish consumption is actually falling. "The main reason for this decline is the stagnation in capture fish production combined with a fast-growing population," says WorldFish Center Deputy Director-General Patrick Dugan. The situation also threatens one of Africa's leading sour...'Shifty-eyed' Monkeys Offer Window Into Brain's Social Reflexes
...eeing a monkey looking in one direction or another actually changes where you're paying attention, then you should shift your gaze faster if the box appears in the direction in which that monkey face was looking and slower in the other direction. Which is exactly what we found with both humans and monkeys.' T...Nose odors and mouth odors: The brain distinguishes
...and thus the pleasant 'taste' to which we refer is actually a pleasant odor sensed retronasally." "The role of olfaction in taste is powerful," they said. For example, they pointed out that pinching the nose while eating or drinking--which blocks airflow from the mouth through the olfactory system--blocks fl...Duke Experiments Boost Radiation's Cancer-Killing Effects
...tically in a cancer cell yields no benefit and can actually impede other cancer treatments," said Dewhirst. "B... middle of summer would yield no benefit and could actually cause harm, blocking HIF-1 at the wrong time and place produces no benefit," said Moeller. "But bloc...IBM Transforms the Art of Scientific Expeditions
...tically in a cancer cell yields no benefit and can actually impede other cancer treatments," said Dewhirst. "B... middle of summer would yield no benefit and could actually cause harm, blocking HIF-1 at the wrong time and place produces no benefit," said Moeller. "But bloc...Bird samples from Mongolia confirmed as H5N1 avian flu
...d little effect on the birds or that very few were actually infected by the bug. Early results suggest that it may be the latter. Supported by the U.N.'s Food and Agriculture Organization (F.A.O.), the team has sent the samples (774 in total) to the U.S.D.A.'s Poultry Research Laboratory in Athens, Georg...MERIS monitoring tracks planetary photosynthesis levels
... solar radiation useful for photosynthesis that is actually absorbed by vegetation ?a value known as the Fraction of Absorbed Photosynthetically Active Radiation (FAPAR) ?is well-recognised as an indicator of its condition and an influence on its capacity for growth, or 'productivity'. FAPAR has been recognis...Researchers predict infinite genomes
.... "But at TIGR, we're now going a step further, to actually quantify how many genes are associated with a given species. How many genomes do you need to fully describe a bacterial species?" In pursuit of that question, TIGR scientist Hervé Tettelin and colleagues published a study in this week's (Sept...Hopkins scientists uncover 'tags' that force proteins to cell surface
...r. "This particular tag and its closest relatives actually mark normal proteins for delivery to the cell surface," says Li. "In some diseases, a protein that should be on the cell surface isn't, and in the lab, sometimes it's proven impossible to get a protein to the cell surface in order to study it. The ta...UF researchers kill resistant bugs one bandage at a time
...ue for bacteria and fungus to grow. This treatment actually makes the gauze absorb a little more fluid, (but) it'll keep the wound cleaner because it will keep the bacteria from getting back into the wound." Clinical trials of the coating in gauze will be conducted at UF later this year. Controlling moistur...Researchers identify genes associated with lung transplant rejection
...et of patients to prove that these biomarker genes actually work. And we're testing that now." Currently, Caughey's research team is studying biopsy samples from more than 100 UCSF lung transplant patients, who regularly undergo biopsies as part of standard follow-up care. Another potential benefit of the re...Old drug, new tricks: Prospects for slashing the impact of malaria
...at many toddlers who seem reasonably healthy might actually have low level malarial infections that are eliminated by Fansidar, allowing the immune system to develop to its full potential." WEHI's Dr James Beeson adds, "Most of the 2 million or so annual deaths from malaria and much of the severe illness in...Several minute intermediate stage in virus-cell fusion discovered; opportunity for drug development
...can be re-evaluated to pinpoint at what stage they actually work, to fine-tune their activity." The experimental set-up for this study was devised by Young and Melikyan last year to investigate viral infection in a manner as close to 'real life' as possible. The researchers filmed the microscopic viruses, wh...Newfound roadblock to interferon effectiveness against malignant melanoma
...lleagues in Current Biology, shows that interferon actually activates STAT5 in melanoma cells but that under normal conditions, this does not interfere with the inhibitory potential of the drug. However, when cancer cells posses too much STAT5 activity to begin with, the further activation of STAT5 function b......rain as well. First he has to find out what they actually do - something that has been notoriously hard to do in the past. Dr Rietze is a finalist in the UQ Foundation Research Excellence Awards, to be announced tomorrow as a highlight of UQ Research Week 2005. He is working on a project with a novel approa...