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Tag: "actually" at biology news

Chemists create 'Superbowl' molecule; May lead to better health

...one knows yet when this experimental molecule will actually enter the consumer market, but any useful application is likely to take five to ten years, the researcher estimates. Administration of the molecule for drug delivery could be by mouth or by injection, he adds. There are hurdles to overcome. The curr...

Scientists ID molecular 'switch' in liver that triggers harmful effects of saturated and trans fats

...n mice fed high-fat diets, the PCG-1beta mechanism actually decreased cholesterol in the liver while increasing it in the bloodstream. "Before this report, it wasn't clear what the differences were between saturated fats and unsaturated fats in their ability to raise cholesterol blood levels," commented Jeff...

Spleen may be source of versatile stem cells

... theautoimmune reaction underlying type 1 diabetes actually cured thedisease in diabetic mice. Late in 2003 th...ls' immune systems not to attackislet cells - were actually producing new islets. The result suggestedthat the adult spleen - previously regarded as playing a f...

Genome of deadly amoeba shows surprising complexity, evidence of lateral gene transfer

...ho ingest amoeba cysts in contaminated fluids will actually develop the disease. "Every aspect of research is changed by having the genome sequenced," says Dr. William A. Petri, Jr., a collaborator who is chief of the University of Virginia Health System's Division of Infectious Diseases. He says the DNA typ...

Antarctic ice shelf retreats happened before

... first evidence that a shift in ocean currents can actually destroy ice shelves. In this case it's possible that a preceding warm period may have primed the ice shelf to disintegrate when the ocean currents shifted.' The scientists analysed sediments from the bottom of a freshwater lake close to the edge of ...

Recent breakthroughs in common adult leukemia highlighted in New England Journal of Medicine

...widely available. The authors note that ZAP-70 may actually be the most reliable indicator of prognosis known to date. After discussing B lymphocytes -- the type of white blood cell that gives rise to CLL, the biology of leukemic lymphocytes and the clinical course of CLL as it relates to the biology, the au...

Plants respond similarly to signals from friends, enemies

...factor, but it appears that the nematodes may have actually acquired genes from rhizobia to exploit this signal pathway," Bird says. ### The research was funded by the National Science Foundation and the North Carolina Research Station. "Root-knot Nematodes and Bacterial Nod Factors Elicit Common Signal Tr...

Bound for destruction: Ubiquitination protects against improper Notch signaling

...e Notch activity during endocytosis, and thatNedd4 actually destabilizes Dx in the presence of Notch. Thiscompetition between two ubiquitin ligases to permit or suppressactivation of a signaling pathway represents a neat solution to theproblem confronting cells of how to prevent molecular loose cannonsfrom fo...

“Nano-scissors?laser shows precise surgical capability

...o other tissue was harmed.To assure the axons were actually cut, and their disappearance wasn’tcaused by discoloration by the laser, the researchers cut axons theyknew would impair the worms?backward motion. The worms couldn’t movebackwards after surgery. But within 24 hours, most of the severed axonsregrew a...

Iron Deficiency Sparks Dramatic Changes In Gene Expression

..., said Thiele."We discovered that iron deprivation actually reprograms the metabolismof the entire cell," said...ins are substituted in place ofCth2 in yeast, they actually assume its function in yeast cells, saidThiele."Yeast cells illuminate for us what to look for in hu...

Scientists find missing enzyme for tuberculosis iron scavenging pathway

... involved in tuberculosis antibiotic resistance is actually a "missing enzyme" from the biosynthetic pathway for an agent used by the bacteria to scavenge iron. The research appears as the "Paper of the Week" in the April 8 issue of the Journal of Biological Chemistry, an American Society for Biochemistry an...

Gene therapy converts dead bone graft to new, living tissue

...," says Schwarz. "It's at that point that the body actually begins changing the dead, foreign bone splint, into the body's own, whole, living bone." Such a transformation can occur because mammals use their skeletons for both support and as a kind of "calcium bank." If calcium, which is necessary for such im...

Molecular machine may lead to new drugs to combat human diseases

...chemistry. Normal genes then can take over without actually changing the genetic code. The results of the Pur... sequences previously believed to have no function actually may play specialized roles in cell behavior. While humans have introns, they don't have Group I int...

Mouse brain tumors mimic those in human genetic disorder

...en used to determine the need fortreatment may not actually be diagnostically informative. "Thesemice develop brain tumors with many of the same features as those seenin children with NF1, and studying those tumors has helped usunderstand the cellular events involved in NF1 brain tumordevelopment," says prin...

Automatic extraction of gene/protein biological functions from biomedical text

...ated recall of 54?4% with a precision of 91?4% for actually described functions in abstracts. When applied to the PUBMED, it extracted over 190 000 gene–GO relationships and 150 000 family–GO relationships for major eukaryotes. Availability: The extracted gene functions are available at http://prime.ontology....

BRCA1 causes ovarian cancer through indirect, biochemical route

..., Dubeau notes, "What we've shown is that the gene actually acts indirectly, that it disrupts interactions bet...ding. The result: ovarian cancer. This finding is actually good news for scientists and physicians trying to figure out new ways to treat ovarian cancer. If th...

In the sea slug's defense against lobsters, confusion is key

... but the mechanisms by which such chemical attacks actually work against their intended targets are not well understood by researchers. New work has now shown that such chemical defenses can involve modes of trickery that had not previously been appreciated as components of chemical defense. When attacked by...

Open microfluidic and nanofluidic systems

...ace channels as microcompartments. However, if one actually tries to fill these channels with a certain liquid, one observes that the liquid often refuses to enter the channels. In fact, as shown in the new PNAS study, liquids at surface channels can attain a large variety of different wetting morphologies in...

Amino acids in nectar enhance butterfly fecundity: A long awaited link

...ds. Recent experiments have shown that butterflies actually prefer nectars with a high amino acid content. The...ition. In order to determine whether butterflies actually need nectar amino acids, researchers from the University of Basel raised map butterfly caterpillars ...

Gene Therapy For Parkinson's Disease Moves Forward In Animals

...n tissue showed the animals' dopamine systems were actually spared by the treatment. “The simplest question w...nerally works great for several years, but then it actually starts creating movement problems,?Mandel said. “Our idea is that instead of taking pills that creat...

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(Date:4/18/2014)... 2014) Benaroya Research Institute at Virginia Mason (BRI) ... particular molecule in metastatic breast cancer reduces both the ... metastases. BRI scientists have found in models of the ... 60 - 80 percent and can keep the tumor ... million five-year grant comes from the National Cancer Institute ...
(Date:4/18/2014)... scientists could lead to potential new treatments for breaking ... , Fibrosis, or scarring, is a hallmark of ... lungs can lead to serious organ damage and, in ... options centers on findings made by Swati Bhattacharyya, PhD, ... that a specific protein plays in promoting fibrosis. ...
(Date:4/17/2014)... new pain relief targets that could be used ... at King,s College London made the discovery when ... periphery of the body. , Dr Marzia Malcangio ... underlying pain generation and our findings could help ... , One potential side effect of some chemotherapy ...
(Date:4/17/2014)... University of California, San Diego School of Medicine report ... suffered a recent major loss are more likely to ... The study is published in this month,s issue of ... Because compassionate behaviors are associated with better health and ... into ways to improve the outcomes of individuals whose ...
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