activity 2 9

Tag: "activity" at biology news

Gambling monkeys give insight into neural machinery of risk

...tion on rewards. They then measured the electrical activity of neurons in the region as they administered the ... increased the riskiness of a target, the neurons' activity would go up in the same way the monkey's frequency of choosing that target would go up. It was amazi...

Carnegie Mellon University research reveals how cells process large genes

...ez said. Recursive splicing relies on the unusual activity of a ratchetting point, a pattern of chemical groups (nucleotides) previously discovered within the genome by Lopez. One end of a ratchetting point contains a sequence of nucleotides similar to the signal normally found at the beginning of an intron....

Stem Cells Found In Cerebellum; Possible Cell of Origin for Childhood Brain Tumors

... cells, we could develop an agent to shut down its activity without disrupting the growth of normal cells," he said. "Chemotherapy targets all dividing cells ?not just those involved in cancer ?so it is highly toxic. Our hope is to provide the basis for less toxic, more targeted therapies." ...

Reversal of role for a viral protein associated with the development of lymphoma

...ez said. Recursive splicing relies on the unusual activity of a ratchetting point, a pattern of chemical groups (nucleotides) previously discovered within the genome by Lopez. One end of a ratchetting point contains a sequence of nucleotides similar to the signal normally found at the beginning of an intron....

Bitter or sweet? The same taste bud can tell the difference

... in Petri dishes in order to record the electrical activity of each cell. They also applied NPY to these cells. Cells are like tiny batteries, as each has its own electrical charge. They compared the resulting electrical signal given off by NPY to what they had found in the earlier work on CCK. "NPY activat...

Lance Armstrong through a physiological lens: hard training boosts muscle power 8%

... skeletal muscle as reflected by a 38% increase in activity of the mitochondrial enzyme citrate synthase," Coy... studies showed increases in citrate synthase (CS) activity and glycogen content after several weeks of sprint interval training with equivocal data, "we show h...

Gene therapy to lower blood pressure just enough

...s limited by the fact that it has such short-lived activity in the blood system." Its activity is halved 30 seconds after it enters the blood stream. Gene therapy can make cells generate more A...

Physical and functional interaction of key cell growth molecules linked to cancer

...vated levels in human cancer cells. Increased EGFR activity has been linked to metastasis and treatment resistance for aggressive human tumors and, as a result, the EGFR has been identified as an attractive target for cancer therapeutics. However, the precise role of EGFR in cancer cell biology has remained e...

'Shifty-eyed' Monkeys Offer Window Into Brain's Social Reflexes

...if social information influences patterns of brain activity there. In future studies, they plan to alter or disrupt neurons or structures in the social-processing regions of the monkeys' brains, and explore whether the resulting behaviors mimic the symptoms of autism. Also, he said, the researchers can explor...

Structures of marine toxins provide insight into their effectiveness as cancer drugs

...ically on deep-sea sponges, work by disrupting the activity of actin, an abundant protein that gives structure to eukaryotic cells. "Actin forms long chains, or filaments, that are essential for cellular locomotion, division and growth," explains Allingham. "Because cancer cell masses grow faster than other ...

Duke Experiments Boost Radiation's Cancer-Killing Effects

... HIF-1 levels, blocking HIF-1 at the height of its activity ?after radiation has occurred -- is the most logic...tes more than 70 genes -- that simply blocking its activity without regard to its myriad effects has yielded conflicting results. Some of HIF-1's effects promot...

IBM Transforms the Art of Scientific Expeditions

... HIF-1 levels, blocking HIF-1 at the height of its activity ?after radiation has occurred -- is the most logic...tes more than 70 genes -- that simply blocking its activity without regard to its myriad effects has yielded conflicting results. Some of HIF-1's effects promot...

Monkeying around to improve organ transplantation

...outside the living organism have immunosuppressive activity in vitro. Now in a study appearing online on June 9 in advance of the print publication of the July 1 print issue of the Journal of Clinical Investigation, Hisashi Bashuda and colleagues from Juntendo University investigate whether this approach can ...

MERIS monitoring tracks planetary photosynthesis levels

...ful Grid computing to reveal global photosynthesis activity on land. This permits researchers to trace the sta...sults shown here indicate a decrease in vegetation activity against the average for Spain and Portugal, due to unusually cold and dry conditions at the beginnin...

Organic farms produce same yields as conventional farms

...ly improved in organic matter, moisture, microbial activity and other soil quality indicators. The fact that organic agriculture systems also absorb and retain significant amounts of carbon in the soil has implications for global warming, Pimentel said, pointing out that soil carbon in the organic systems in...

Hormones and growth: The control of body size and developmental growth rate in fruit flies

...heir findings, the investigators conclude that Ras activity in the prothoracic gland regulates body size and developmental rate by regulating ecdysone release. In the second study, Christen Mirth, James W. Truman, and Lynn M. Riddiford address how developing flies sense that they have reached the proper size...

Why do aneurysms form? New studies suggest leading role for white blood cells

...aller. The researchers also looked at the levels, activity and production of enzymes before and during the aneurysm formation. For two of the matrix metalloproteinases, there was no difference between the two kinds of mice. For one called MMP-8, though, much less was produced in the neutrophil-deficient mice...

New bioinformatics technique for systematically analyzing key regions in DNA that help control gene activity

...dely studied organisms." From the analysis of gene activity under a variety of environmental conditions, the teams were able to develop a set of rules for predicting the location of binding site combinations based on limited binding site and gene expression data. "We found that the same transcription factors...

UIC developing drug for SARS

...ine whether and how quickly they slow the enzymes' activity inside living cells. The prototype drug developed earlier by Ghosh, an inhibitor of 3CLpro, was an improvement on a design published in the scientific literature. Shipped to the Centers for Disease Control and Prevention for testing on a live virus,...

Newfound roadblock to interferon effectiveness against malignant melanoma

.... However, when cancer cells posses too much STAT5 activity to begin with, the further activation of STAT5 function by interferon induces a mechanism that blocks the ability of the drug to effectively inhibit growth. Confirming this initial finding, the researchers found that when they inhibited STAT5 in int...

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