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Tag: "activity" at biology news

Weill Cornell Research Reveals Secrets Of Trafficking Within Cells

...th bits of RNA; and microscopy, which looks at the activity of individual living cells by attaching a fluorescent tag to a specific cell component -- in this case clathrin. "This means that now we could suddenly look at a much broader dynamic range of activity," Dr. Ryan said. "Instead of it being an 'all or...

First-ever Compounds To Target Only Metastatic Cells Are Highly Effective Against Breast, Prostate, And Colon Cancers

...n the cell-migration process," Dr. Huang said. The activity of a migration-linked protein called Rac appears to be much reduced in cancer cells affected by the analogues, and the researchers also noticed that malignant cells failed to grow tiny "antennas," called lamellipodia, another crucial step in the migr...

Critical role in programmed cell death identified

... set the cell death program in motion. While their activity in mammalian cell death was known, mitochondrial involvement in worms had not previously been shown. The new work, led by Dr. Barbara Conradt, assistant professor of genetics at Dartmouth Medical School, reveals the importance of mitochondria in cel...

Genetically modified natural killer immune cells attack, kill leukemia cells

... set off a reaction that super-charged the killing activity of the NK cell. "By developing a technique for cultivating large numbers of NK cells from a small blood sample, we made it practical to consider them a potential treatment against many different types of cancer," Campana said. "By genetically modify...

Highly adaptable genome in gut bacterium key to intestinal health

...ates and low in simple sugars. Ten days later, the activity of all genes in the bacterial genome was surveyed ...iet--and then inoculated with B. theta, the genome activity analysis showed that B. theta had adaptively switched on a different set of genes encoding surface p...

Researchers add new tool to tumor-treatment arsenal

...nd its derivatives have shown promising anti-tumor activity in phase I and II clinical trials. RAD001 lowers the amount of DNA-damaging agent needed by blocking p53's DNA-repair function, automatically killing the cancer cells when agents like cisplatin are introduced. "These findings provide the rationale ...

MSI releases 'moleculizer' - a new approach to simulation of intracellular biochemical networks

...lations can also aidbiologists in viewing cellular activity over a period of time, bytaking advantage of the power of computers to generate the thousands ofpotential protein complexes and reactions that cells are able togenerate.The Molecular Sciences Institute is an independent nonprofit researchlaboratory t...

Jumping gene helps explain immune system's abilities

...ehindantigen diversity might have evolved from the activity of a jumpinggene, likely a close relative of Hermes."Recognition of so many antigens allows the immune system to fightinfection and distinguish friend from foe. The "big picture" behindthis ability is that cells build proteins called antibodies that ...

UCSD Discovery Shows How Embryonic Stem Cells Perform 'Quality Control' Inspections

...ehindantigen diversity might have evolved from the activity of a jumpinggene, likely a close relative of Hermes."Recognition of so many antigens allows the immune system to fightinfection and distinguish friend from foe. The "big picture" behindthis ability is that cells build proteins called antibodies that ...

New therapy for HIV/AIDS eliminates needles and excessive toxicity

...ehindantigen diversity might have evolved from the activity of a jumpinggene, likely a close relative of Hermes."Recognition of so many antigens allows the immune system to fightinfection and distinguish friend from foe. The "big picture" behindthis ability is that cells build proteins called antibodies that ...

Gene sequencing explains bioremediation 'bug'

...ehindantigen diversity might have evolved from the activity of a jumpinggene, likely a close relative of Hermes."Recognition of so many antigens allows the immune system to fightinfection and distinguish friend from foe. The "big picture" behindthis ability is that cells build proteins called antibodies that ...

New insight into people who 'see' colors in letters and numbers

...her blood flow in the brain, which reflects higher activity in those regions. Importantly, the researchers found evidence suggesting that synesthetes may be quite different from one another, which the researchers said "has profound implications for the studies of synesthesia that group together data from mul...

Beyond lithium for bipolar disorder

...f Merck and Co., Inc.) have identified genes whose activity appears to be switched on by lithium, suggesting m...ior. The protein also has been found to affect the activity of a key neurotransmitter, dopamine, in the brain, said the researchers. What's more, they found two...

International trial of two microbicides begins

...Pharmaceuticals, Lexington, MA, PRO 2000 has shown activity against HIV and other STIs in both laboratory and animal testing. It is believed to act by inhibiting the entry of HIV and other pathogens into body cells. BufferGel, a product of ReProtect, Inc., Baltimore, MD, boosts the natural acidity of the vagi...

MetaChip provides quick, efficient toxicity screening of potential drugs

...Pharmaceuticals, Lexington, MA, PRO 2000 has shown activity against HIV and other STIs in both laboratory and animal testing. It is believed to act by inhibiting the entry of HIV and other pathogens into body cells. BufferGel, a product of ReProtect, Inc., Baltimore, MD, boosts the natural acidity of the vagi...

The very unexpected life and death of a leukemic cell

... rate at which CLL cells are born and the clinical activity or progression of the disease in a patient. The disease activity may vary over time and this may be the result of fluctuations in birth and/or death rates of the CLL...

New RNA polymerase discovered in plants

...erent from the other RNA polymerases, the rules of activity are different for Pol IV." Pikaard said the Pol IV has a perfect match in rice, the only other plant genome to be sequenced, despite rice being a monocotyledon and Arabidopsis a dicotyledon. "These two plants diverged 200 million years ago, and the...

Bird Brains Show How Trial and Error May Contribute to Learning

...roject had noticed greater and more variable brain activity when the finches were singing to themselves compar...e relationship between song and the natural neural activity of LMAN during the two types of male finch song, the performance-quality song directed at females, a...

The Bacteria's guide to survival

...ny tugs on cell membranes. The study examined gene activity in human epithelial cells infected with Neisseria ...rs found a subset of 52 host genes that had higher activity when the host was infected with the normal bacteria, suggesting that the pulls of the pili were resp...

TEL2 gene cooperates with MYC gene to provoke B-cell lymphomas

...ongly suggest that physicians should look for TEL2 activity in a patient's B-cells as part of the diagnosis of...suicide. This situation occurs when increased TEL2 activity reduces the cell's ability to trigger apoptosis in response to relentless prodding by MYC to keep mu...

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